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exaly
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Npj Systems Biology and Applications
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top-articles
Npj Systems Biology and Applications
4.1
(top 10%)
impact factor
387
(top 50%)
papers
5.4K
(top 20%)
citations
38
(top 20%)
h
-index
4.2
(top 10%)
extended IF
404
all documents
6.7K
doc citations
56
(top 20%)
g
-index
Top Articles
#
Title
Journal
Year
Citations
1
L1000CDS2: LINCS L1000 characteristic direction signatures search engine
Npj Systems Biology and Applications
2016
250
2
Synthetic and systems biology for microbial production of commodity chemicals
Npj Systems Biology and Applications
2016
187
3
A machine learning approach to predict metabolic pathway dynamics from time-series multiomics data
Npj Systems Biology and Applications
2018
161
4
Regulation of amino-acid metabolism controls flux to lipid accumulation in Yarrowia lipolytica
Npj Systems Biology and Applications
2016
141
5
Combinatorial interventions inhibit TGFβ-driven epithelial-to-mesenchymal transition and support hybrid cellular phenotypes
Npj Systems Biology and Applications
2015
122
6
Mechanisms of action of sacubitril/valsartan on cardiac remodeling: a systems biology approach
Npj Systems Biology and Applications
2017
96
7
From expression footprints to causal pathways: contextualizing large signaling networks with CARNIVAL
Npj Systems Biology and Applications
2019
96
8
Systems medicine disease maps: community-driven comprehensive representation of disease mechanisms
Npj Systems Biology and Applications
2018
84
9
Identifying inhibitors of epithelial–mesenchymal plasticity using a network topology-based approach
Npj Systems Biology and Applications
2020
80
10
iOmicsPASS: network-based integration of multiomics data for predictive subnetwork discovery
Npj Systems Biology and Applications
2019
79
11
The multiplex network of human diseases
Npj Systems Biology and Applications
2019
77
12
Food allergen detection by mass spectrometry: the role of systems biology
Npj Systems Biology and Applications
2016
72
13
Prevalence and patterns of higher-order drug interactions in Escherichia coli
Npj Systems Biology and Applications
2018
71
14
VEGFR1 promotes cell migration and proliferation through PLCγ and PI3K pathways
Npj Systems Biology and Applications
2018
69
15
MINERVA—a platform for visualization and curation of molecular interaction networks
Npj Systems Biology and Applications
2016
68
16
From START to FINISH: computational analysis of cell cycle control in budding yeast
Npj Systems Biology and Applications
2015
66
17
The NAD World 2.0: the importance of the inter-tissue communication mediated by NAMPT/NAD+/SIRT1 in mammalian aging and longevity control
Npj Systems Biology and Applications
2016
66
18
Multi-experiment nonlinear mixed effect modeling of single-cell translation kinetics after transfection
Npj Systems Biology and Applications
2018
66
19
A landscape view on the interplay between EMT and cancer metastasis
Npj Systems Biology and Applications
2018
66
20
Combinatorial perturbation analysis reveals divergent regulations of mesenchymal genes during epithelial-to-mesenchymal transition
Npj Systems Biology and Applications
2019
65
21
Gene co-expression in the interactome: moving from correlation toward causation via an integrated approach to disease module discovery
Npj Systems Biology and Applications
2021
64
22
Multipartite viruses: adaptive trick or evolutionary treat?
Npj Systems Biology and Applications
2017
62
23
Population-based mechanistic modeling allows for quantitative predictions of drug responses across cell types
Npj Systems Biology and Applications
2018
62
24
Flux sampling is a powerful tool to study metabolism under changing environmental conditions
Npj Systems Biology and Applications
2019
62
25
Mechanistic insights into bacterial metabolic reprogramming from omics-integrated genome-scale models
Npj Systems Biology and Applications
2020
62
26
Systems biology driving drug development: from design to the clinical testing of the anti-ErbB3 antibody seribantumab (MM-121)
Npj Systems Biology and Applications
2017
61
27
Mitigating the risk of cytokine release syndrome in a Phase I trial of CD20/CD3 bispecific antibody mosunetuzumab in NHL: impact of translational system modeling
Npj Systems Biology and Applications
2020
61
28
From metagenomic data to personalized in silico microbiotas: predicting dietary supplements for Crohn’s disease
Npj Systems Biology and Applications
2018
59
29
Performance of objective functions and optimisation procedures for parameter estimation in system biology models
Npj Systems Biology and Applications
2017
57
30
Pathways on demand: automated reconstruction of human signaling networks
Npj Systems Biology and Applications
2016
55
31
Meta-analysis of host response networks identifies a common core in tuberculosis
Npj Systems Biology and Applications
2017
55
32
Improved prediction of PARP inhibitor response and identification of synergizing agents through use of a novel gene expression signature generation algorithm
Npj Systems Biology and Applications
2017
55
33
Integrating personalized gene expression profiles into predictive disease-associated gene pools
Npj Systems Biology and Applications
2017
54
34
Sparsely-connected autoencoder (SCA) for single cell RNAseq data mining
Npj Systems Biology and Applications
2021
53
35
On the performance of de novo pathway enrichment
Npj Systems Biology and Applications
2017
51
36
Classification of gene signatures for their information value and functional redundancy
Npj Systems Biology and Applications
2018
50
37
ROS networks: designs, aging, Parkinson’s disease and precision therapies
Npj Systems Biology and Applications
2020
50
38
A data-driven, knowledge-based approach to biomarker discovery: application to circulating microRNA markers of colorectal cancer prognosis
Npj Systems Biology and Applications
2018
47
39
Clinical responses to ERK inhibition in BRAF V600E-mutant colorectal cancer predicted using a computational model
Npj Systems Biology and Applications
2017
45
40
A diseasome cluster-based drug repurposing of soluble guanylate cyclase activators from smooth muscle relaxation to direct neuroprotection
Npj Systems Biology and Applications
2018
45
41
Role of noise and parametric variation in the dynamics of gene regulatory circuits
Npj Systems Biology and Applications
2018
44
42
Dynamic models of the complex microbial metapopulation of lake mendota
Npj Systems Biology and Applications
2016
43
43
A multiscale model of early cell lineage specification including cell division
Npj Systems Biology and Applications
2017
43
44
A roadmap towards personalized immunology
Npj Systems Biology and Applications
2018
43
45
ComPath: an ecosystem for exploring, analyzing, and curating mappings across pathway databases
Npj Systems Biology and Applications
2018
43
46
Metabolic modelling reveals broad changes in gut microbial metabolism in inflammatory bowel disease patients with dysbiosis
Npj Systems Biology and Applications
2021
43
47
A time-resolved molecular map of the macrophage response to VSV infection
Npj Systems Biology and Applications
2016
42
48
A method to identify and analyze biological programs through automated reasoning
Npj Systems Biology and Applications
2016
42
49
Large-scale computational drug repositioning to find treatments for rare diseases
Npj Systems Biology and Applications
2018
40
50
Predicting ligand-dependent tumors from multi-dimensional signaling features
Npj Systems Biology and Applications
2017
39
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