| # | Title | Journal | Year | Citations |
|---|
| 1 | Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the ‘phosphocreatine circuit’ for cellular energy homeostasis | Biochemical Journal | 1992 | 1,827 |
| 2 | Hybridization and speciation | Journal of Evolutionary Biology | 2013 | 1,735 |
| 3 | Linking Crystallographic Model and Data Quality | Science | 2012 | 1,637 |
| 4 | Asymmetric paralog evolution between the “cryptic” gene Bmp16 and its well-studied sister genes Bmp2 and Bmp4 | Scientific Reports | 2019 | 1,637 |
| 5 | DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells | Cancer Research | 2001 | 1,528 |
| 6 | Towards complete and error-free genome assemblies of all vertebrate species | Nature | 2021 | 1,139 |
| 7 | From 2R to 3R: evidence for a fish-specific genome duplication (FSGD) | BioEssays | 2005 | 929 |
| 8 | Scientists' warning on invasive alien species | Biological Reviews | 2020 | 928 |
| 9 | The evolutionary significance of ancient genome duplications | Nature Reviews Genetics | 2009 | 919 |
| 10 | The genomic substrate for adaptive radiation in African cichlid fish | Nature | 2014 | 874 |
| 11 | Genomics and the origin of species | Nature Reviews Genetics | 2014 | 850 |
| 12 | The Path from β-Carotene to Carlactone, a Strigolactone-Like Plant Hormone | Science | 2012 | 809 |
| 13 | SHAPE ANALYSIS OF SYMMETRIC STRUCTURES: QUANTIFYING VARIATION AMONG INDIVIDUALS AND ASYMMETRY | Evolution; International Journal of Organic Evolution | 2002 | 804 |
| 14 | The effects of phenotypic plasticity and local adaptation on forecasts of species range shifts under climate change | Ecology Letters | 2014 | 802 |
| 15 | Genome Duplication, a Trait Shared by 22,000 Species of Ray-Finned Fish | Genome Research | 2003 | 787 |
| 16 | Moving in the Anthropocene: Global reductions in terrestrial mammalian movements | Science | 2018 | 783 |
| 17 | Global exchange and accumulation of non-native plants | Nature | 2015 | 746 |
| 18 | Global trends of whole-genome duplications revealed by the ciliate Paramecium tetraurelia | Nature | 2006 | 744 |
| 19 | Gene and genome duplications in vertebrates: the one-to-four (-to-eight in fish) rule and the evolution of novel gene functions | Current Opinion in Cell Biology | 1999 | 738 |
| 20 | A physiological role for DNA supercoiling in the osmotic regulation of gene expression in S. typhimurium and E. coli | Cell | 1988 | 736 |
| 21 | Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser | Nature | 2015 | 683 |
| 22 | Myosin isoforms, muscle fiber types, and transitions | Microscopy Research and Technique | 2000 | 682 |
| 23 | The African coelacanth genome provides insights into tetrapod evolution | Nature | 2013 | 612 |
| 24 | Enhanced Peroxynitrite Formation Is Associated with Vascular Aging | Journal of Experimental Medicine | 2000 | 607 |
| 25 | Survival of hunger and stress: The role of rpoS in early stationary phase gene regulation in E. coli | Cell | 1993 | 595 |
| 26 | Sequencing of the sea lamprey (Petromyzon marinus) genome provides insights into vertebrate evolution | Nature Genetics | 2013 | 588 |
| 27 | Sympatric speciation in Nicaraguan crater lake cichlid fish | Nature | 2006 | 579 |
| 28 | Maltose/Maltodextrin System ofEscherichia coli: Transport, Metabolism, and Regulation | Microbiology and Molecular Biology Reviews | 1998 | 556 |
| 29 | The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons | Nature Genetics | 2016 | 545 |
| 30 | Machine behaviour | Nature | 2019 | 536 |
| 31 | Phylogenetic Timing of the Fish-Specific Genome Duplication Correlates with the Diversification of Teleost Fish | Journal of Molecular Evolution | 2004 | 533 |
| 32 | A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis | Nature Medicine | 2009 | 533 |
| 33 | Structural Asymmetry of AcrB Trimer Suggests a Peristaltic Pump Mechanism | Science | 2006 | 512 |
| 34 | Formation of large, ion-permeable membrane channels by the matrix protein (porin) of Escherichia coli | Biochimica Et Biophysica Acta - Biomembranes | 1978 | 493 |
| 35 | The genomic landscape underlying phenotypic integrity in the face of gene flow in crows | Science | 2014 | 490 |
| 36 | The cellular concentration of the sigma S subunit of RNA polymerase in Escherichia coli is controlled at the levels of transcription, translation, and protein stability. | Genes and Development | 1994 | 485 |
| 37 | Comparative genomics provides evidence for an ancient genome duplication event in fish | Philosophical Transactions of the Royal Society B: Biological Sciences | 2001 | 450 |
| 38 | The OxyS regulatory RNA represses rpoS translation and binds the Hfq (HF-I) protein | EMBO Journal | 1998 | 436 |
| 39 | Physiological implications of arginine metabolism in plants | Frontiers in Plant Science | 2015 | 435 |
| 40 | Transgenerational impact of intimate partner violence on methylation in the promoter of the glucocorticoid receptor | Translational Psychiatry | 2011 | 433 |
| 41 | Retinoic Acid Production by Endocardium and Epicardium Is an Injury Response Essential for Zebrafish Heart Regeneration | Developmental Cell | 2011 | 431 |
| 42 | The complete connectome of a learning and memory centre in an insect brain | Nature | 2017 | 424 |
| 43 | Global rise in emerging alien species results from increased accessibility of new source pools | Proceedings of the National Academy of Sciences of the United States of America | 2018 | 416 |
| 44 | COVID-19 lockdown allows researchers to quantify the effects of human activity on wildlife | Nature Ecology and Evolution | 2020 | 413 |
| 45 | Immuno- and Constitutive Proteasome Crystal Structures Reveal Differences in Substrate and Inhibitor Specificity | Cell | 2012 | 410 |
| 46 | Key Questions in Marine Megafauna Movement Ecology | Trends in Ecology and Evolution | 2016 | 397 |
| 47 | Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination | Nature Communications | 2013 | 382 |
| 48 | Origin, Spread and Demography of the Mycobacterium tuberculosis Complex | PLoS Pathogens | 2008 | 378 |
| 49 | Ion transport through pores: A rate-theory analysis | Biochimica Et Biophysica Acta - Biomembranes | 1973 | 372 |
| 50 | Adaptation in the age of ecological genomics: insights from parallelism and convergence | Trends in Ecology and Evolution | 2011 | 366 |
