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Top Articles

#TitleJournalYearCitations
1Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolutionGenes To Cells20111,215
2AAA+superfamily ATPases: common structure-diverse functionGenes To Cells2001864
3Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophilesGenes To Cells2003698
4The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathwayGenes To Cells2003651
5Hierarchy of Atg proteins in pre-autophagosomal structure organizationGenes To Cells2007602
6Two major Smad pathways in TGF-β superfamily signallingGenes To Cells2002594
7Role of Bcl-2 family proteins in apoptosis: apoptosomes or mitochondria?Genes To Cells1998591
8Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6 -deficient miceGenes To Cells1999574
9Loss of teratogenic response to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking the Ah (dioxin) receptorGenes To Cells2003539
10Restricted feeding entrains liver clock without participation of the suprachiasmatic nucleusGenes To Cells2001489
11Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3bGenes To Cells2006482
12Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcriptionGenes To Cells2001415
13Semaphorin3A signalling is mediated via sequential Cdk5 and GSK3β phosphorylation of CRMP2: implication of common phosphorylating mechanism underlying axon guidance and Alzheimer's diseaseGenes To Cells2005377
14Phosphorylation of Ser‐3 of cofilin regulates its essential function on actinGenes To Cells1996363
15Signalling from endoplasmic reticulum to nucleus: transcription factor with a basic-leucine zipper motif is required for the unfolded protein-response pathwayGenes To Cells1996352
16Structural basis of target recognition by Atg8/LC3 during selective autophagyGenes To Cells2008349
17p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondriaGenes To Cells2010345
18Identification of an imprinted gene, Meg3 /Gtl2 and its human homologue MEG3 , first mapped on mouse distal chromosome 12 and human chromosome 14qGenes To Cells2000343
19Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domainGenes To Cells1999342
20Mitogen-activated protein kinase p38 defines the common senescence-signalling pathwayGenes To Cells2003338
21The N-end rule pathway of protein degradationGenes To Cells1997328
22A possible linkage between AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) signalling pathwayGenes To Cells2003319
23Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 systemGenes To Cells2002298
24Rad52 forms ring structures and co‐operates with RPA in single‐strand DNA annealingGenes To Cells1998295
25Comparative analysis of the self-incompatibility (S -) locus region of Prunus mume : identification of a pollen-expressed F-box gene with allelic diversityGenes To Cells2003295
26Nrf2-deficient mice are highly susceptible to cigarette smoke-induced emphysemaGenes To Cells2005293
27Aurora-B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensationGenes To Cells2002292
28Dissociation of raptor from mTOR is a mechanism of rapamycin-induced inhibition of mTOR functionGenes To Cells2004274
29Axin, an inhibitor of the Wnt signalling pathway, interacts with β-catenin, GSK-3β and APC and reduces the β-catenin levelGenes To Cells1998272
30PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complexGenes To Cells2001266
31Identical origin of adrenal cortex and gonad revealed by expression profiles of Ad4BP/SF‐1Genes To Cells1996258
32Oocyte growth-dependent progression of maternal imprinting in miceGenes To Cells2006257
33Essential role for ERK2 mitogen-activated protein kinase in placental developmentGenes To Cells2003253
34The master control gene for morphogenesis and evolution of the eyeGenes To Cells1996250
35Two closely-related left-right asymmetrically expressed genes,lefty-1andlefty-2: their distinct expression domains, chromosomal linkage and direct neuralizing activity inXenopusembryosGenes To Cells1997246
36The superoxide-producing NAD(P)H oxidase Nox4 in the nucleus of human vascular endothelial cellsGenes To Cells2005246
37Initiation of Sendai virus multiplication from transfected cDNA or RNA with negative or positive senseGenes To Cells1996245
38Interaction of hREV1 with three human Y-family DNA polymerasesGenes To Cells2004244
39Induction of IRF-3/-7 kinase and NF-κB in response to double-stranded RNA and virus infection: common and unique pathwaysGenes To Cells2001242
40A yeast gene product, Fob1 protein, required for both replication fork blocking and recombinational hotspot activitiesGenes To Cells1996241
41Cytoskeletal reorganization by soluble Wnt‐3a protein signallingGenes To Cells1998240
42Myosin II activation promotes neurite retraction during the action of Rho and Rho‐kinaseGenes To Cells1998236
43Molecular beacon aptamer fluoresces in the presence of Tat protein of HIV-1Genes To Cells2000236
44Identification of a BMP-responsive element inId1, the gene for inhibition of myogenesisGenes To Cells2002226
45Mapping of early firing origins on a replication profile of budding yeastGenes To Cells2002223
46Roles of Toll-like receptors in innate immune responsesGenes To Cells2001222
47Both G3BP1 and G3BP2 contribute to stress granule formationGenes To Cells2013222
48Structures of D14 and D14L in the strigolactone and karrikin signaling pathwaysGenes To Cells2013221
49Essential and non‐redundant roles of p48 (ISGF3γ) and IRF‐1 in both type I and type II interferon responses, as revealed by gene targeting studiesGenes To Cells1996215
50Structural basis for improved efficacy of therapeutic antibodies on defucosylation of their Fc glycansGenes To Cells2011213