| # | Title | Journal | Year | Citations |
|---|
|
| 1 | Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution | Genes To Cells | 2011 | 1,262 |
| 2 | AAA+superfamily ATPases: common structure-diverse function | Genes To Cells | 2001 | 875 |
| 3 | Keap1 regulates both cytoplasmic‐nuclear shuttling and degradation of Nrf2 in response to electrophiles | Genes To Cells | 2003 | 711 |
| 4 | The receptor tyrosine kinase Ror2 is involved in non‐canonical Wnt5a/JNK signalling pathway | Genes To Cells | 2003 | 663 |
| 5 | Hierarchy of Atg proteins in pre-autophagosomal structure organization | Genes To Cells | 2007 | 610 |
| 6 | Role of Bcl‐2 family proteins in apoptosis: apoptosomes or mitochondria? | Genes To Cells | 1998 | 608 |
| 7 | Two major Smad pathways in TGF‐β superfamily signalling | Genes To Cells | 2002 | 599 |
| 8 | Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6 -deficient mice | Genes To Cells | 1999 | 582 |
| 9 | Loss of teratogenic response to 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin (TCDD) in mice lacking the Ah (dioxin) receptor | Genes To Cells | 1997 | 549 |
| 10 | Restricted feeding entrains liver clock without participation of the suprachiasmatic nucleus | Genes To Cells | 2001 | 498 |
| 11 | Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b | Genes To Cells | 2006 | 495 |
| 12 | Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription | Genes To Cells | 2001 | 433 |
| 13 | Semaphorin3A signalling is mediated via sequential Cdk5 and GSK3β phosphorylation of CRMP2: implication of common phosphorylating mechanism underlying axon guidance and Alzheimer's disease | Genes To Cells | 2005 | 382 |
| 14 | Phosphorylation of Ser‐3 of cofilin regulates its essential function on actin | Genes To Cells | 1996 | 366 |
| 15 | Structural basis of target recognition by Atg8/LC3 during selective autophagy | Genes To Cells | 2008 | 358 |
| 16 | p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria | Genes To Cells | 2010 | 355 |
| 17 | Signalling from endoplasmic reticulum to nucleus: transcription factor with a basic-leucine zipper motif is required for the unfolded protein-response pathway | Genes To Cells | 1996 | 354 |
| 18 | Identification of an imprinted gene, Meg3/Gtl2 and its human homologue MEG3, first mapped on mouse distal chromosome 12 and human chromosome 14q | Genes To Cells | 2000 | 348 |
| 19 | Cytokine‐inducible SH2 protein‐3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N‐terminal kinase inhibitory region as well as SH2 domain | Genes To Cells | 1999 | 346 |
| 20 | Mitogen-activated protein kinase p38 defines the common senescence-signalling pathway | Genes To Cells | 2003 | 344 |
| 21 | The N‐end rule pathway of protein degradation | Genes To Cells | 1997 | 330 |
| 22 | A possible linkage between AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) signalling pathway | Genes To Cells | 2003 | 320 |
| 23 | Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system | Genes To Cells | 2002 | 304 |
| 24 | Comparative analysis of the self-incompatibility (S -) locus region of Prunus mume : identification of a pollen-expressed F-box gene with allelic diversity | Genes To Cells | 2003 | 302 |
| 25 | Nrf2-deficient mice are highly susceptible to cigarette smoke-induced emphysema | Genes To Cells | 2005 | 299 |
| 26 | Aurora‐B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation | Genes To Cells | 2002 | 296 |
| 27 | Rad52 forms ring structures and co‐operates with RPA in single‐strand DNA annealing | Genes To Cells | 1998 | 295 |
| 28 | Dissociation of raptor from mTOR is a mechanism of rapamycin‐induced inhibition of mTOR function | Genes To Cells | 2004 | 276 |
| 29 | Axin, an inhibitor of the Wnt signalling pathway, interacts with β-catenin, GSK-3β and APC and reduces the β-catenin level | Genes To Cells | 1998 | 275 |
| 30 | PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex | Genes To Cells | 2001 | 268 |
| 31 | Identical origin of adrenal cortex and gonad revealed by expression profiles of Ad4BP/SF‐1 | Genes To Cells | 1996 | 261 |
| 32 | Oocyte growth‐dependent progression of maternal imprinting in mice | Genes To Cells | 2006 | 258 |
| 33 | Essential role for ERK2 mitogen‐activated protein kinase in placental development | Genes To Cells | 2003 | 255 |
| 34 | The master control gene for morphogenesis and evolution of the eye | Genes To Cells | 1996 | 252 |
| 35 | The superoxide-producing NAD(P)H oxidase Nox4 in the nucleus of human vascular endothelial cells | Genes To Cells | 2005 | 250 |
| 36 | Interaction of hREV1 with three human Y-family DNA polymerases | Genes To Cells | 2004 | 248 |
| 37 | Initiation of Sendai virus multiplication from transfected cDNA or RNA with negative or positive sense | Genes To Cells | 1996 | 246 |
| 38 | Two closely‐related left‐right asymmetrically expressed genes, lefty‐1 and lefty‐2: their distinct expression domains, chromosomal linkage and direct neuralizing activity in Xenopus embryos | Genes To Cells | 1997 | 246 |
| 39 | A yeast gene product, Fob1 protein, required for both replication fork blocking and recombinational hotspot activities | Genes To Cells | 1996 | 243 |
| 40 | Induction of IRF-3/-7 kinase and NF-κB in response to double-stranded RNA and virus infection: common and unique pathways | Genes To Cells | 2001 | 243 |
| 41 | Cytoskeletal reorganization by soluble Wnt‐3a protein signalling | Genes To Cells | 1998 | 241 |
| 42 | Myosin II activation promotes neurite retraction during the action of Rho and Rho‐kinase | Genes To Cells | 1998 | 237 |
| 43 | Molecular beacon aptamer fluoresces in the presence of Tat protein of HIV-1 | Genes To Cells | 2000 | 236 |
| 44 | Both G3BP1 and G3BP2 contribute to stress granule formation | Genes To Cells | 2013 | 230 |
| 45 | Identification of a BMP-responsive element inId1, the gene for inhibition of myogenesis | Genes To Cells | 2002 | 229 |
| 46 | Mapping of early firing origins on a replication profile of budding yeast | Genes To Cells | 2002 | 227 |
| 47 | Roles of Toll-like receptors in innate immune responses | Genes To Cells | 2001 | 225 |
| 48 | Structures of D14 and D14L in the strigolactone and karrikin signaling pathways | Genes To Cells | 2013 | 225 |
| 49 | A new mammalianperiodgene predominantly expressed in the suprachiasmatic nucleus | Genes To Cells | 1998 | 219 |
| 50 | Structural basis for improved efficacy of therapeutic antibodies on defucosylation of their Fc glycans | Genes To Cells | 2011 | 219 |
