| 1 | A rapid method for the isolation of functional thymus‐derived murine lymphocytes | European Journal of Immunology | 1973 | 3,381 |
| 2 | Derivation of specific antibody‐producing tissue culture and tumor lines by cell fusion | European Journal of Immunology | 1976 | 1,418 |
| 3 | F4/80, a monoclonal antibody directed specifically against the mouse macrophage | European Journal of Immunology | 1981 | 1,257 |
| 4 | „Natural”︁ killer cells in the mouse. I. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Specificity and distribution according to genotype | European Journal of Immunology | 1975 | 1,215 |
| 5 | Nanoparticles target distinct dendritic cell populations according to their size | European Journal of Immunology | 2008 | 1,028 |
| 6 | Production of hybridoma growth factor by human monocytes | European Journal of Immunology | 1987 | 932 |
| 7 | Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors | European Journal of Immunology | 1988 | 904 |
| 8 | Mac-1: a macrophage differentiation antigen identified by monoclonal antibody | European Journal of Immunology | 1979 | 871 |
| 9 | Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions | European Journal of Immunology | 1997 | 848 |
| 10 | A plaque assay for all cells secreting Ig of a given type or class | European Journal of Immunology | 1976 | 832 |
| 11 | Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) | European Journal of Immunology | 2019 | 779 |
| 12 | Transient expression of FOXP3 in human activated nonregulatory CD4 + T cells | European Journal of Immunology | 2007 | 767 |
| 13 | „Natural”︁ killer cells in the mouse. II. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Characteristics of the killer cell | European Journal of Immunology | 1975 | 756 |
| 14 | Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation | European Journal of Immunology | 1998 | 755 |
| 15 | CD69: from activation marker to metabolic gatekeeper | European Journal of Immunology | 2017 | 740 |
| 16 | IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis | European Journal of Immunology | 2006 | 722 |
| 17 | The rapid isolation of clonable antigen-specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis | European Journal of Immunology | 1981 | 677 |
| 18 | Excessive production of interleukin 6/B cell stimulatory factor-2 in rheumatoid arthritis | European Journal of Immunology | 1988 | 647 |
| 19 | Historical insights into cytokines | European Journal of Immunology | 2007 | 638 |
| 20 | IL‐10 and TGF‐β cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy | European Journal of Immunology | 2003 | 637 |
| 21 | The somatic generation of immune recognition | European Journal of Immunology | 1971 | 632 |
| 22 | CD4 + CD25 + regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative | European Journal of Immunology | 2004 | 632 |
| 23 | The who's who of T‐cell differentiation: Human memory T‐cell subsets | European Journal of Immunology | 2013 | 624 |
| 24 | Identification of CpG oligonucleotide sequences with high induction of IFN-α/β in plasmacytoid dendritic cells | European Journal of Immunology | 2001 | 607 |
| 25 | Vaccination with cytotoxic T lymphocyte epitope-containing peptide protects against a tumor induced by human papillomavirus type 16-transformed cells | European Journal of Immunology | 1993 | 585 |
| 26 | Transgenic mice with hematopoietic and lymphoid specific expression of Cre | European Journal of Immunology | 2003 | 583 |
| 27 | DNA methylation controls Foxp3 gene expression | European Journal of Immunology | 2008 | 570 |
| 28 | Fusion between immunoglobulin-secreting and nonsecreting myeloma cell lines | European Journal of Immunology | 1976 | 564 |
| 29 | Universally immunogenic T cell epitopes: promiscuous binding to human MHC class II and promiscuous recognition by T cells | European Journal of Immunology | 1989 | 550 |
| 30 | On the cellular source and function of interleukin 6 produced in the central nervous system in viral diseases | European Journal of Immunology | 1989 | 546 |
| 31 | Identification of Ia glycoproteins in rat thymus and purification from rat spleen | European Journal of Immunology | 1979 | 543 |
| 32 | Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells | European Journal of Immunology | 1998 | 542 |
| 33 | Two subsets of rat T lymphocytes defined with monoclonal antibodies | European Journal of Immunology | 1980 | 525 |
| 34 | Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells | European Journal of Immunology | 2001 | 514 |
| 35 | Antigen presentation and tumor cytotoxicity by interferon‐γ‐treated microglial cells | European Journal of Immunology | 1987 | 501 |
| 36 | Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12 | European Journal of Immunology | 2001 | 501 |
| 37 | Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments | European Journal of Immunology | 2002 | 497 |
| 38 | In vivo quercitrin anti‐inflammatory effect involves release of quercetin, which inhibits inflammation through down‐regulation of the NF‐κB pathway | European Journal of Immunology | 2005 | 496 |
| 39 | Interleukin‐12 is produced by dendritic cells and mediates T helper 1 development as well as interferon‐γ production by T helper 1 cells | European Journal of Immunology | 1996 | 493 |
| 40 | PD-1:PD-L inhibitory pathway affects both CD4+ and CD8+ T cells and is overcome by IL-2 | European Journal of Immunology | 2002 | 489 |
| 41 | Signaling by ROS drives inflammasome activation | European Journal of Immunology | 2010 | 485 |
| 42 | Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens | European Journal of Immunology | 1991 | 482 |
| 43 | Increased cytokine production in mononuclear cells of healthy elderly people | European Journal of Immunology | 1993 | 482 |
| 44 | IgE‐induced histamine release from rat basophilic leukemia cell lines: isolation of releasing and nonreleasing clones | European Journal of Immunology | 1981 | 481 |
| 45 | Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens | European Journal of Immunology | 1978 | 476 |
| 46 | Cyclosporin A mediates immunosuppression of primary cytotoxic T cell responses by impairing the release of interleukin 1 and interleukin 2 | European Journal of Immunology | 1981 | 474 |
| 47 | Caspase‐11 activates a canonical NLRP3 inflammasome by promoting K
+
efflux | European Journal of Immunology | 2015 | 474 |
| 48 | Regulation of PD-1, PD-L1, and PD-L2 expression during normal and autoimmune responses | European Journal of Immunology | 2003 | 471 |
| 49 | Bone marrow mesenchymal progenitor cells inhibit lymphocyte proliferation by activation of the programmed death 1 pathway | European Journal of Immunology | 2005 | 470 |
| 50 | Distinct patterns and kinetics of chemokine production regulate dendritic cell function | European Journal of Immunology | 1999 | 454 |