| 1 | Sepsis and septic shock—A review of laboratory models and a proposal | Journal of Surgical Research | 1980 | 1,123 |
| 2 | The Role of Vascular Endothelial Growth Factor in Wound Healing | Journal of Surgical Research | 2009 | 950 |
| 3 | Prolonged operative duration is associated with complications: a systematic review and meta-analysis | Journal of Surgical Research | 2018 | 749 |
| 4 | Accumulating deficits model of frailty and postoperative mortality and morbidity: its application to a national database | Journal of Surgical Research | 2013 | 672 |
| 5 | Clinical applications of magnetic drug targeting. | Journal of Surgical Research | 2001 | 603 |
| 6 | Significance of M2-Polarized Tumor-Associated Macrophage in Pancreatic Cancer | Journal of Surgical Research | 2011 | 438 |
| 7 | Small intestinal submucosa as a large diameter vascular graft in the dog | Journal of Surgical Research | 1989 | 415 |
| 8 | Laboratory models of sepsis and septic shock | Journal of Surgical Research | 1990 | 402 |
| 9 | Quantification of DNA in Biologic Scaffold Materials | Journal of Surgical Research | 2009 | 365 |
| 10 | Preparation of chronic lung lymph fistulas in sheep | Journal of Surgical Research | 1975 | 350 |
| 11 | Therapeutic Potential of Chitosan and Its Derivatives in Regenerative Medicine | Journal of Surgical Research | 2006 | 338 |
| 12 | Loss of the Tight Junction Protein ZO-1 in Dextran Sulfate Sodium Induced Colitis | Journal of Surgical Research | 2007 | 336 |
| 13 | Normal Intraabdominal Pressure in Healthy Adults | Journal of Surgical Research | 2005 | 333 |
| 14 | Pediatric Thyroid Carcinoma: Incidence and Outcomes in 1753 Patients | Journal of Surgical Research | 2009 | 323 |
| 15 | Hemodynamic effects of increased abdominal pressure | Journal of Surgical Research | 1981 | 313 |
| 16 | Surgical Site Infections: Reanalysis of Risk Factors | Journal of Surgical Research | 2002 | 298 |
| 17 | Perioperative Anemia: An Independent Risk Factor for Infection, Mortality, and Resource Utilization in Surgery | Journal of Surgical Research | 2002 | 293 |
| 18 | Immersive Virtual Reality for Surgical Training: A Systematic Review | Journal of Surgical Research | 2021 | 289 |
| 19 | Influence of Storage on Red Blood Cell Rheological Properties | Journal of Surgical Research | 2002 | 285 |
| 20 | Mechanisms of Focal Heat Destruction of Liver Tumors | Journal of Surgical Research | 2005 | 285 |
| 21 | The effect of occlusive dressings on collagen synthesis and re-epithelialization in superficial wounds | Journal of Surgical Research | 1983 | 281 |
| 22 | Vascular endothelial growth factor is the major angiogenic factor in omentum: mechanism of the omentum-mediated angiogenesis. | Journal of Surgical Research | 1997 | 281 |
| 23 | Factors in the Pathophysiology of the Liver Ischemia-Reperfusion Injury | Journal of Surgical Research | 2008 | 281 |
| 24 | The role of Osteopontin in tumor metastasis | Journal of Surgical Research | 2004 | 270 |
| 25 | The role of glutamine in maintaining a healthy gut and supporting the metabolic response to injury and infection | Journal of Surgical Research | 1990 | 263 |
| 26 | Impact of Polymer Pore Size on the Interface Scar Formation in a Rat Model | Journal of Surgical Research | 2002 | 263 |
| 27 | Remote Ischemic Preconditioning: A Novel Protective Method From Ischemia Reperfusion Injury—A Review | Journal of Surgical Research | 2008 | 263 |
| 28 | MMP-8 Is the Predominant Collagenase in Healing Wounds and Nonhealing Ulcers | Journal of Surgical Research | 1999 | 250 |
| 29 | Three-dimensional printing in surgery: a review of current surgical applications | Journal of Surgical Research | 2015 | 248 |
| 30 | Bioactive Interleukin-8 Is Expressed in Wounds and Enhances Wound Healing | Journal of Surgical Research | 2000 | 242 |
| 31 | Mechanical properties of acellular peripheral nerve | Journal of Surgical Research | 2003 | 240 |
| 32 | Changes in visceral blood flow with elevated intraabdominal pressure | Journal of Surgical Research | 1987 | 232 |
| 33 | Hemodynamic and respiratory alterations with increased intra-abdominal pressure | Journal of Surgical Research | 1976 | 224 |
| 34 | Regulation of Intestinal Blood Flow | Journal of Surgical Research | 2000 | 223 |
| 35 | Nitric oxide regulates wound healing. | Journal of Surgical Research | 1996 | 222 |
| 36 | Studies of wound healing in experimental diabetes mellitus | Journal of Surgical Research | 1977 | 221 |
| 37 | The use of silicone rubber as a carrier for prolonged drug therapy | Journal of Surgical Research | 1964 | 220 |
| 38 | Morphologic Study of Small Intestinal Submucosa as a Body Wall Repair Device | Journal of Surgical Research | 2002 | 219 |
| 39 | A modified frailty index to assess morbidity and mortality after lobectomy | Journal of Surgical Research | 2013 | 219 |
| 40 | Quantitative Study of Changes in Intestinal Morphology and Mucus Gel on Total Parenteral Nutrition in Rats | Journal of Surgical Research | 2000 | 216 |
| 41 | The socioeconomic effects of an iliofemoral venous thrombosis | Journal of Surgical Research | 1977 | 213 |
| 42 | Recombinant basic fibroblast growth factor accelerates wound healing. | Journal of Surgical Research | 1988 | 212 |
| 43 | Changing epidemiology of acute appendicitis in the United States: study period 1993-2008. | Journal of Surgical Research | 2012 | 210 |
| 44 | A Closer Look Into Global Hospital Beds Capacity and Resource Shortages During the COVID-19 Pandemic | Journal of Surgical Research | 2021 | 209 |
| 45 | Diabetes impairs the late inflammatory response to wound healing | Journal of Surgical Research | 1991 | 207 |
| 46 | The analysis and presentation of surgical results by actuarial methods | Journal of Surgical Research | 1974 | 204 |
| 47 | Esophageal Reconstruction with ECM and Muscle Tissue in a Dog Model | Journal of Surgical Research | 2005 | 202 |
| 48 | Sepsis and Major Abdominal Surgery Lead to Flaking of the Endothelial Glycocalix | Journal of Surgical Research | 2011 | 202 |
| 49 | VEGF Improves Myocardial Blood Flow but Produces EDRF-Mediated Hypotension in Porcine Hearts | Journal of Surgical Research | 1996 | 200 |
| 50 | The Effect of Hepatic Vascular Inflow Occlusion on Liver Tissue pH, Carbon Dioxide, and Oxygen Partial Pressures: Defining the Optimal Clamp/Release Regime for Intermittent Portal Clamping | Journal of Surgical Research | 2007 | 199 |