| # | Title | Journal | Year | Citations |
|---|
| 1 | Repertoires of Autophagy in the Pathogenesis of Ocular Diseases | Cellular Physiology and Biochemistry | 2015 | 11,181 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 4 | Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment | Cancer Cell | 2017 | 1,282 |
| 5 | Prevalence of mental disorders in China: a cross-sectional epidemiological study | Lancet Psychiatry,the | 2019 | 1,273 |
| 6 | Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins | Nature Medicine | 2004 | 1,200 |
| 7 | Experimental design and analysis and their reporting II: updated and simplified guidance for authors and peer reviewers | British Journal of Pharmacology | 2018 | 1,122 |
| 8 | Clinical characteristics of 24 asymptomatic infections with COVID-19 screened among close contacts in Nanjing, China | Science China Life Sciences | 2020 | 1,090 |
| 9 | Long non-coding RNAs: A new frontier in the study of human diseases | Cancer Letters | 2013 | 1,041 |
| 10 | ceRNA in cancer: possible functions and clinical implications | Journal of Medical Genetics | 2015 | 1,031 |
| 11 | Generation of Gene-Modified Cynomolgus Monkey via Cas9/RNA-Mediated Gene Targeting in One-Cell Embryos | Cell | 2014 | 930 |
| 12 | Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing | Nature | 2013 | 859 |
| 13 | Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancer | Molecular Cancer | 2014 | 840 |
| 14 | YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs | ELife | 2017 | 815 |
| 15 | Serum MicroRNA Signatures Identified in a Genome-Wide Serum MicroRNA Expression Profiling Predict Survival of Non–Small-Cell Lung Cancer | Journal of Clinical Oncology | 2010 | 759 |
| 16 | Randomized, Double-Blind, Placebo-Controlled Phase III Trial of Apatinib in Patients With Chemotherapy-Refractory Advanced or Metastatic Adenocarcinoma of the Stomach or Gastroesophageal Junction | Journal of Clinical Oncology | 2016 | 756 |
| 17 | Surface functionalized exosomes as targeted drug delivery vehicles for cerebral ischemia therapy | Biomaterials | 2018 | 739 |
| 18 | Ythdc2 is an N6-methyladenosine binding protein that regulates mammalian spermatogenesis | Cell Research | 2017 | 696 |
| 19 | Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells | Nature | 2019 | 681 |
| 20 | Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci | Nature Genetics | 2018 | 652 |
| 21 | VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation | Cell Discovery | 2018 | 643 |
| 22 | Pre-Pregnancy Body Mass Index in Relation to Infant Birth Weight and Offspring Overweight/Obesity: A Systematic Review and Meta-Analysis | PLoS ONE | 2013 | 629 |
| 23 | Prussian Blue Nanoparticles as Multienzyme Mimetics and Reactive Oxygen Species Scavengers | Journal of the American Chemical Society | 2016 | 611 |
| 24 | The prevalence of neuropsychiatric symptoms in Alzheimer's disease: Systematic review and meta-analysis | Journal of Affective Disorders | 2016 | 601 |
| 25 | Role of pro-inflammatory cytokines released from microglia in Alzheimer's disease | Annals of Translational Medicine | 2015 | 593 |
| 26 | ARRIVE 2.0 and the British Journal of Pharmacology: Updated guidance for 2020 | British Journal of Pharmacology | 2020 | 580 |
| 27 | lncRNA-MIAT Regulates Microvascular Dysfunction by Functioning as a Competing Endogenous RNA | Circulation Research | 2015 | 557 |
| 28 | Neuronal nitric oxide synthase: Structure, subcellular localization, regulation, and clinical implications | Nitric Oxide - Biology and Chemistry | 2009 | 544 |
| 29 | Prognostic Value of Fractional Flow Reserve | Journal of the American College of Cardiology | 2014 | 513 |
| 30 | Nanoparticle-Based Drug Delivery in Cancer Therapy and Its Role in Overcoming Drug Resistance | Frontiers in Molecular Biosciences | 2020 | 510 |
| 31 | Sucrose preference test for measurement of stress-induced anhedonia in mice | Nature Protocols | 2018 | 502 |
| 32 | CircHIPK3 promotes colorectal cancer growth and metastasis by sponging miR-7 | Cell Death and Disease | 2018 | 497 |
| 33 | Breast Cancer: Epidemiology and Etiology | Cell Biochemistry and Biophysics | 2015 | 487 |
| 34 | Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes | Nature Genetics | 2017 | 472 |
| 35 | Akkermansia muciniphila is a promising probiotic | Microbial Biotechnology | 2019 | 447 |
| 36 | The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer | Nature Cell Biology | 2016 | 444 |
| 37 | Fabrication techniques for microfluidic paper-based analytical devices and their applications for biological testing: A review | Biosensors and Bioelectronics | 2016 | 441 |
| 38 | LncRNA HOXA11-AS Promotes Proliferation and Invasion of Gastric Cancer by Scaffolding the Chromatin Modification Factors PRC2, LSD1, and DNMT1 | Cancer Research | 2016 | 436 |
| 39 | Reactive Oxygen Species Regulate Angiogenesis and Tumor Growth through Vascular Endothelial Growth Factor | Cancer Research | 2007 | 433 |
| 40 | The mechanisms of sorafenib resistance in hepatocellular carcinoma: theoretical basis and therapeutic aspects | Signal Transduction and Targeted Therapy | 2020 | 433 |
| 41 | An emerging function of circRNA-miRNAs-mRNA axis in human diseases | Oncotarget | 2017 | 429 |
| 42 | Obesity, inflammation, and liver cancer | Journal of Hepatology | 2012 | 428 |
| 43 | Co-infection with respiratory pathogens among COVID-2019 cases | Virus Research | 2020 | 419 |
| 44 | MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation | Journal of Clinical Investigation | 2015 | 418 |
| 45 | Birth weight and subsequent risk of obesity: a systematic review and meta‐analysis | Obesity Reviews | 2011 | 408 |
| 46 | MiR-21 Induced Angiogenesis through AKT and ERK Activation and HIF-1α Expression | PLoS ONE | 2011 | 408 |
| 47 | N 6 -methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription | Science | 2020 | 406 |
| 48 | The regulation of immune tolerance by FOXP3 | Nature Reviews Immunology | 2017 | 398 |
| 49 | Heterologous prime–boost vaccination | Current Opinion in Immunology | 2009 | 397 |
| 50 | Association of antipsychotic druginduced weight gain with a 5-HT2C receptor gene polymorphism | Lancet, The | 2002 | 392 |
