| # | Title | Journal | Year | Citations |
|---|
| 1 | Recent advances in three‐dimensional multicellular spheroid culture for biomedical research | Biotechnology Journal | 2008 | 1,025 |
| 2 | Rapid heterogeneous liver-cell on-chip patterning via the enhanced field-induced dielectrophoresis trap | Lab on A Chip | 2006 | 272 |
| 3 | Sequencing and analysis of the large virulence plasmid pLVPK of Klebsiella pneumoniae CG43 | Gene | 2004 | 263 |
| 4 | Dynamic analysis of hepatoma spheroid formation: roles of E-cadherin and β1-integrin | Cell and Tissue Research | 2006 | 239 |
| 5 | RmpA Regulation of Capsular Polysaccharide Biosynthesis inKlebsiella pneumoniaeCG43 | Journal of Bacteriology | 2010 | 190 |
| 6 | Echinoid Is a Component of Adherens Junctions That Cooperates with DE-Cadherin to Mediate Cell Adhesion | Developmental Cell | 2005 | 169 |
| 7 | Phosphorylation of the arginine/serine dipeptide‐rich motif of the severe acute respiratory syndrome coronavirus nucleocapsid protein modulates its multimerization, translation inhibitory activity and cellular localization | FEBS Journal | 2008 | 146 |
| 8 | An Experimentally Validated Genome-Scale Metabolic Reconstruction of Klebsiella pneumoniae MGH 78578, i YL1228 | Journal of Bacteriology | 2011 | 132 |
| 9 | Combined Use of MS-222 (Tricaine) and Isoflurane Extends Anesthesia Time and Minimizes Cardiac Rhythm Side Effects in Adult Zebrafish | Zebrafish | 2010 | 108 |
| 10 | Overexpression of Lon contributes to survival and aggressive phenotype of cancer cells through mitochondrial complex I-mediated generation of reactive oxygen species | Cell Death and Disease | 2013 | 105 |
| 11 | Flavones inhibit breast cancer proliferation through the Akt/FOXO3a signaling pathway | BMC Cancer | 2015 | 105 |
| 12 | Characterization of the Histidine-containing Phosphotransfer Protein B-mediated Multistep Phosphorelay System in Pseudomonas aeruginosa PAO1 | Journal of Biological Chemistry | 2008 | 98 |
| 13 | Heterotypic Gap Junctions between Two Neurons in the Drosophila Brain Are Critical for Memory | Current Biology | 2011 | 97 |
| 14 | Role of Chronic Inflammation in Myopia Progression: Clinical Evidence and Experimental Validation | EBioMedicine | 2016 | 89 |
| 15 | Dielectrophoresis based-cell patterning for tissue engineering | Biotechnology Journal | 2006 | 88 |
| 16 | Folate-conjugated gene-carrying microbubbles with focused ultrasound for concurrent blood-brain barrier opening and local gene delivery | Biomaterials | 2016 | 88 |
| 17 | 4β-Hydroxywithanolide E from Physalis peruviana (golden berry) inhibits growth of human lung cancer cells through DNA damage, apoptosis and G2/M arrest | BMC Cancer | 2010 | 86 |
| 18 | A flexible hydrophilic-modified graphene microprobe for neural and cardiac recording | Nanomedicine: Nanotechnology, Biology, and Medicine | 2013 | 86 |
| 19 | Emodin inhibits the growth of hepatoma cells: Finding the common anti-cancer pathway using Huh7, Hep3B, and HepG2 cells | Biochemical and Biophysical Research Communications | 2010 | 82 |
| 20 | miRNA-34c-5p inhibits amphiregulin-induced ovarian cancer stemness and drug resistance via downregulation of the AREG-EGFR-ERK pathway | Oncogenesis | 2017 | 81 |
| 21 | A Network Map of FGF-1/FGFR Signaling System | Journal of Signal Transduction | 2014 | 80 |
| 22 | Current progress of mitochondrial transplantation that promotes neuronal regeneration | Translational Neurodegeneration | 2019 | 78 |
| 23 | Electrical stimulation promotes nerve growth factor-induced neurite outgrowth and signaling | Biochimica Et Biophysica Acta - General Subjects | 2013 | 76 |
| 24 | A novel miR-365-3p/EHF/keratin 16 axis promotes oral squamous cell carcinoma metastasis, cancer stemness and drug resistance via enhancing β5-integrin/c-met signaling pathway | Journal of Experimental and Clinical Cancer Research | 2019 | 74 |
| 25 | A microfluidic chip with a U-shaped microstructure array for multicellular spheroid formation, culturing and analysis | Biofabrication | 2014 | 72 |
| 26 | Enhanced cell viability and cell adhesion using low conductivity medium for negative dielectrophoretic cell patterning | Biotechnology Journal | 2010 | 68 |
| 27 | Discovery of a Novel Family of SARS-CoV Protease Inhibitors by Virtual Screening and 3D-QSAR Studies | Journal of Medicinal Chemistry | 2006 | 67 |
| 28 | Genetic Requirements for Klebsiella pneumoniae-Induced Liver Abscess in an Oral Infection Model | Infection and Immunity | 2009 | 67 |
| 29 | Flexible carbon nanotubes electrode for neural recording | Biosensors and Bioelectronics | 2009 | 64 |
| 30 | Novel Antiviral Agent DTriP-22 Targets RNA-Dependent RNA Polymerase of Enterovirus 71 | Antimicrobial Agents and Chemotherapy | 2009 | 64 |
| 31 | Angiogenesis-targeting microbubbles combined with ultrasound-mediated gene therapy in brain tumors | Journal of Controlled Release | 2017 | 64 |
| 32 | Polygonum cuspidatum and Its Active Components Inhibit Replication of the Influenza Virus through Toll-Like Receptor 9-Induced Interferon Beta Expression | PLoS ONE | 2015 | 63 |
| 33 | Neuroglian activates Echinoid to antagonize the Drosophila EGF receptor signaling pathway | Development (Cambridge) | 2003 | 57 |
| 34 | DNA ligation of ultramicro volume using an EWOD microfluidic system with coplanar electrodes | Journal of Micromechanics and Microengineering | 2008 | 57 |
| 35 | Capsule deletion via a λ-Red knockout system perturbs biofilm formation and fimbriae expression in Klebsiella pneumoniae MGH 78578 | BMC Research Notes | 2014 | 57 |
| 36 | Targeting Coronaviral Replication and Cellular JAK2 Mediated Dominant NF-κB Activation for Comprehensive and Ultimate Inhibition of Coronaviral Activity | Scientific Reports | 2017 | 57 |
| 37 | Ca v 3.2 T-type calcium channel is required for the NFAT-dependent Sox9 expression in tracheal cartilage | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 55 |
| 38 | Screening of aptamers specific to colorectal cancer cells and stem cells by utilizing On-chip Cell-SELEX | Scientific Reports | 2015 | 53 |
| 39 | Spatiotemporal manipulation of ciliary glutamylation reveals its roles in intraciliary trafficking and Hedgehog signaling | Nature Communications | 2018 | 53 |
| 40 | Sonogenetic Modulation of Cellular Activities Using an Engineered Auditory-Sensing Protein | Nano Letters | 2020 | 52 |
| 41 | Fern Plant–Derived Protoapigenone Leads to DNA Damage, Apoptosis, and G2/M Arrest in Lung Cancer Cell Line H1299 | DNA and Cell Biology | 2009 | 51 |
| 42 | Improving the adhesion of carbon nanotubes to a substrate using microwave treatment | Carbon | 2010 | 51 |
| 43 | Magnetic Reconstruction of Three-Dimensional Tissues from Multicellular Spheroids | Tissue Engineering - Part C: Methods | 2008 | 50 |
| 44 | Magnetic bead-based DNA detection with multi-layers quantum dots labeling for rapid detection of Escherichia coli O157:H7 | Biosensors and Bioelectronics | 2008 | 49 |
| 45 | Near-infrared nanosecond-pulsed laser-activated highly efficient intracellular delivery mediated by nano-corrugated mushroom-shaped gold-coated polystyrene nanoparticles | Nanoscale | 2020 | 49 |
| 46 | Cholestane-3β, 5α, 6β-triol Suppresses Proliferation, Migration, and Invasion of Human Prostate Cancer Cells | PLoS ONE | 2013 | 49 |
| 47 | Effect of visual experience on the maturation of ON–OFF direction selective ganglion cells in the rabbit retina | Vision Research | 2008 | 48 |
| 48 | Genomic-wide analysis of lymphatic metastasis-associated genes in human hepatocellular carcinoma | World Journal of Gastroenterology | 2009 | 48 |
| 49 | A three-dimensional flexible microprobe array for neural recording assembled through electrostatic actuation | Lab on A Chip | 2011 | 46 |
| 50 | c-Jun-mediated anticancer mechanisms of tylophorine | Carcinogenesis | 2013 | 46 |
