# | Title | Journal | Year | Citations |
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1 | Nanoparticle-mediated brain drug delivery: Overcoming blood–brain barrier to treat neurodegenerative diseases | Journal of Controlled Release | 2016 | 1,018 |
2 | Statins for the primary prevention of cardiovascular disease | The Cochrane Library | 2021 | 933 |
3 | Intranasal Drug Delivery: How, Why and What for? | Journal of Pharmacy and Pharmaceutical Sciences | 2009 | 427 |
4 | Chronic periodontitis, inflammatory cytokines, and interrelationship with other chronic diseases | Postgraduate Medicine | 2018 | 291 |
5 | Next-generation Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence | Journal of Allergy and Clinical Immunology | 2020 | 272 |
6 | Inflammatory Effects of High and Moderate Intensity Exercise—A Systematic Review | Frontiers in Physiology | 2019 | 235 |
7 | Thermoresponsive chitosan–agarose hydrogel for skin regeneration | Carbohydrate Polymers | 2014 | 226 |
8 | Hormonal control of Sertoli cell metabolism regulates spermatogenesis | Cellular and Molecular Life Sciences | 2013 | 161 |
9 | MicroRNA-124 loaded nanoparticles enhance brain repair in Parkinson's disease | Journal of Controlled Release | 2016 | 144 |
10 | Dextran-based hydrogel containing chitosan microparticles loaded with growth factors to be used in wound healing | Materials Science and Engineering C | 2013 | 143 |
11 | 2019 ARIA Care pathways for allergen immunotherapy | Allergy: European Journal of Allergy and Clinical Immunology | 2019 | 140 |
12 | Nanosystems in nose-to-brain drug delivery: A review of non-clinical brain targeting studies | Journal of Controlled Release | 2018 | 138 |
13 | Helichrysum italicum: From traditional use to scientific data | Journal of Ethnopharmacology | 2014 | 126 |
14 | Antioxidant Activity of Lignin Phenolic Compounds Extracted from Kraft and Sulphite Black Liquors | Molecules | 2010 | 108 |
15 | Allergic Rhinitis and its Impact on Asthma (ARIA) Phase 4 (2018): Change management in allergic rhinitis and asthma multimorbidity using mobile technology | Journal of Allergy and Clinical Immunology | 2019 | 103 |
16 | GNAS Mutations in Pseudohypoparathyroidism Type 1a and Related Disorders | Human Mutation | 2015 | 101 |
17 | Tubular Fluid Secretion in the Seminiferous Epithelium: Ion Transporters and Aquaporins in Sertoli Cells | Journal of Membrane Biology | 2010 | 100 |
18 | Impact on Mental Health Due to COVID-19 Pandemic: Cross-Sectional Study in Portugal and Brazil | International Journal of Environmental Research and Public Health | 2020 | 93 |
19 | Metabolic modulation induced by oestradiol and DHT in immature rat Sertoli cells culturedin vitro | Bioscience Reports | 2012 | 91 |
20 | Associations between Medical Student Empathy and Personality: A Multi-Institutional Study | PLoS ONE | 2014 | 90 |
21 | Vaginal Films for Drug Delivery | Journal of Pharmaceutical Sciences | 2013 | 83 |
22 | ESR/ERS statement paper on lung cancer screening | European Radiology | 2020 | 83 |
23 | Effects of apparent temperature on daily mortality in Lisbon and Oporto, Portugal | Environmental Health | 2010 | 81 |
24 | Guidance to 2018 good practice: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma | Clinical and Translational Allergy | 2019 | 81 |
25 | Histamine induces microglia activation and dopaminergic neuronal toxicity via H1 receptor activation | Journal of Neuroinflammation | 2016 | 76 |
26 | Endoscopic Sinus Surgery for Chronic Rhinosinusitis with Nasal Polyps: Clinical Outcome and Predictive Factors of Recurrence | American Journal of Rhinology and Allergy | 2017 | 71 |
27 | Melatonin alters the glycolytic profile of Sertoli cells: implications for male fertility | Molecular Human Reproduction | 2014 | 70 |
28 | Huperzine A from Huperzia serrata: a review of its sources, chemistry, pharmacology and toxicology | Phytochemistry Reviews | 2016 | 70 |
29 | COVID-19-Related Fear and Anxiety: Spiritual-Religious Coping in Healthcare Workers in Portugal | International Journal of Environmental Research and Public Health | 2021 | 69 |
30 | Histamine: a new immunomodulatory player in the neuron-glia crosstalk | Frontiers in Cellular Neuroscience | 2014 | 68 |
31 | Retinoic acid-loaded polymeric nanoparticles induce neuroprotection in a mouse model for Parkinson's disease | Frontiers in Aging Neuroscience | 2015 | 67 |
32 | Clinical improvement following therapy for periodontitis: Association with a decrease in IL-1 and IL-6 | Experimental and Therapeutic Medicine | 2014 | 66 |
33 | Association between ACE D allele and elite short distance swimming | European Journal of Applied Physiology | 2009 | 65 |
34 | Advances and challenges in retinoid delivery systems in regenerative and therapeutic medicine | Nature Communications | 2020 | 65 |
35 | Lack of association of vitamin D receptor gene polymorphisms with susceptibility to type 1 diabetes mellitus in the Portuguese population | Human Immunology | 2008 | 62 |
36 | Statins and the risk of type 2 diabetes mellitus: cohort study using the UK clinical practice pesearch datalink | BMC Cardiovascular Disorders | 2014 | 62 |
37 | The anti-Candida activity of Thymbra capitata essential oil: Effect upon pre-formed biofilm | Journal of Ethnopharmacology | 2012 | 59 |
38 | ESR/ERS statement paper on lung cancer screening | European Respiratory Journal | 2020 | 57 |
39 | ARIA‐EAACI statement on asthma and COVID‐19 (June 2, 2020) | Allergy: European Journal of Allergy and Clinical Immunology | 2021 | 57 |
40 | MicroRNA: Basic concepts and implications for regeneration and repair of neurodegenerative diseases | Biochemical Pharmacology | 2017 | 55 |
41 | Clinical insights gained by refining the 2016 WHO classification of diffuse gliomas with: EGFR amplification, TERT mutations, PTEN deletion and MGMT methylation | BMC Cancer | 2019 | 55 |
42 | Impact of Neuroinflammation on Hippocampal Neurogenesis: Relevance to Aging and Alzheimer’s Disease | Journal of Alzheimer's Disease | 2017 | 54 |
43 | Resveratrol against Arcobacter butzleri and Arcobacter cryaerophilus: Activity and effect on cellular functions | International Journal of Food Microbiology | 2014 | 53 |
44 | Anti-biofilm activity of low-molecular weight chitosan hydrogel against Candida species | Medical Microbiology and Immunology | 2014 | 53 |
45 | Clinical Applications of Artificial Intelligence—An Updated Overview | Journal of Clinical Medicine | 2022 | 53 |
46 | STEP 61 is a substrate of the E3 ligase parkin and is upregulated in Parkinson’s disease | Proceedings of the National Academy of Sciences of the United States of America | 2015 | 52 |
47 | Studies and methodologies on vaginal drug permeation | Advanced Drug Delivery Reviews | 2015 | 52 |
48 | ARIA pharmacy 2018 “Allergic rhinitis care pathways for community pharmacy” | Allergy: European Journal of Allergy and Clinical Immunology | 2019 | 52 |
49 | Testosterone deficiency induced by progressive stages of diabetes mellitus impairs glucose metabolism and favors glycogenesis in mature rat Sertoli cells | International Journal of Biochemistry and Cell Biology | 2015 | 50 |
50 | Bacterial vaginosis, aerobic vaginitis, vaginal inflammation and major Pap smear abnormalities | European Journal of Clinical Microbiology and Infectious Diseases | 2016 | 50 |