| # | Title | Journal | Year | Citations |
|---|
|
| 1 | Emerging threats and persistent conservation challenges for freshwater biodiversity | Biological Reviews | 2019 | 2,037 |
| 2 | Saturated Solutions For the Control of Humidity in Biological Research | Ecology | 1960 | 1,569 |
| 3 | Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use | Nature Genetics | 2019 | 1,443 |
| 4 | Deblur Rapidly Resolves Single-Nucleotide Community Sequence Patterns | MSystems | 2017 | 1,441 |
| 5 | 3D printing with polymers: Challenges among expanding options and opportunities | Dental Materials | 2016 | 1,256 |
| 6 | Consistent effects of nitrogen amendments on soil microbial communities and processes across biomes | Global Change Biology | 2012 | 982 |
| 7 | Test sensitivity is secondary to frequency and turnaround time for COVID-19 screening | Science Advances | 2021 | 958 |
| 8 | The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α | Cell | 2010 | 901 |
| 9 | EDUCATION: Scientific Teaching | Science | 2004 | 798 |
| 10 | Sequence of a Drosophila segmentation gene: protein structure homology with DNA-binding proteins | Nature | 1984 | 749 |
| 11 | Using chlorophyll fluorescence to assess the fraction of absorbed light allocated to thermal dissipation of excess excitation | Physiologia Plantarum | 2008 | 682 |
| 12 | Variable effects of nitrogen additions on the stability and turnover of soil carbon | Nature | 2002 | 658 |
| 13 | Plant diversity predicts beta but not alpha diversity of soil microbes across grasslands worldwide | Ecology Letters | 2015 | 649 |
| 14 | Model-informed COVID-19 vaccine prioritization strategies by age and serostatus | Science | 2021 | 639 |
| 15 | Experimental and analytical tools for studying the human microbiome | Nature Reviews Genetics | 2012 | 621 |
| 16 | Expression of neurogenin3 reveals an islet cell precursor population in the pancreas | Development (Cambridge) | 2000 | 614 |
| 17 | Transcriptional regulation by hypoxia inducible factors | Critical Reviews in Biochemistry and Molecular Biology | 2014 | 613 |
| 18 | Terrestrial biosphere models need better representation of vegetation phenology: results from the North American Carbon Program Site Synthesis | Global Change Biology | 2012 | 600 |
| 19 | Subsampled open-reference clustering creates consistent, comprehensive OTU definitions and scales to billions of sequences | PeerJ | 2014 | 561 |
| 20 | Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders | Nature Neuroscience | 2018 | 539 |
| 21 | Using QIIME to Analyze 16S rRNA Gene Sequences from Microbial Communities | Current Protocols in Bioinformatics | 2011 | 534 |
| 22 | Noise Pollution Changes Avian Communities and Species Interactions | Current Biology | 2009 | 515 |
| 23 | Microbes as Engines of Ecosystem Function: When Does Community Structure Enhance Predictions of Ecosystem Processes? | Frontiers in Microbiology | 2016 | 504 |
| 24 | Using QIIME to Analyze 16S rRNA Gene Sequences from Microbial Communities | Current Protocols in Microbiology | 2012 | 499 |
| 25 | Basic helix-loop-helix genes in neural development | Current Opinion in Neurobiology | 1997 | 490 |
| 26 | Chloroplast DNA systematics: a review of methods and data analysis | American Journal of Botany | 1994 | 489 |
| 27 | NeuroD is required for differentiation of the granule cells in the cerebellum and hippocampus | Genes and Development | 1999 | 489 |
| 28 | Enzymes with extra talents: moonlighting functions and catalytic promiscuity | Current Opinion in Chemical Biology | 2003 | 489 |
| 29 | Changes in Hypothalamic KiSS-1 System and Restoration of Pubertal Activation of the Reproductive Axis by Kisspeptin in Undernutrition | Endocrinology | 2005 | 484 |
| 30 | No Support for Historical Candidate Gene or Candidate Gene-by-Interaction Hypotheses for Major Depression Across Multiple Large Samples | American Journal of Psychiatry | 2019 | 474 |
| 31 | PROGRAMMED CELL DEATH IN PLANT-PATHOGEN INTERACTIONS | Annual Review of Plant Biology | 1997 | 469 |
| 32 | Integrating biodiversity distribution knowledge: toward a global map of life | Trends in Ecology and Evolution | 2012 | 456 |
| 33 | Three-dimensional ultrastructural analysis of the Saccharomyces cerevisiae mitotic spindle. | Journal of Cell Biology | 1995 | 453 |
| 34 | A Broadly Implementable Research Course in Phage Discovery and Genomics for First-Year Undergraduate Students | MBio | 2014 | 444 |
| 35 | Multiple dynamin family members collaborate to drive mitochondrial division | Nature | 2016 | 441 |
| 36 | Unexpected Diversity and Complexity of the Guerrero Negro Hypersaline Microbial Mat | Applied and Environmental Microbiology | 2006 | 439 |
| 37 | Ki67 is a Graded Rather than a Binary Marker of Proliferation versus Quiescence | Cell Reports | 2018 | 437 |
| 38 | An altered intestinal mucosal microbiome in HIV-1 infection is associated with mucosal and systemic immune activation and endotoxemia | Mucosal Immunology | 2014 | 422 |
| 39 | Characterization of the Potent Luteinizing Hormone-Releasing Activity of KiSS-1 Peptide, the Natural Ligand of GPR54 | Endocrinology | 2005 | 417 |
| 40 | The Saccharomyces cerevisiae spindle pole body duplication gene MPS1 is part of a mitotic checkpoint. | Journal of Cell Biology | 1996 | 410 |
| 41 | Species divergence and the measurement of microbial diversity | FEMS Microbiology Reviews | 2008 | 410 |
| 42 | A whole-mount immunocytochemical analysis of the expression of the intermediate filament protein vimentin in Xenopus | Development (Cambridge) | 1989 | 410 |
| 43 | Polyploidy can drive rapid adaptation in yeast | Nature | 2015 | 401 |
| 44 | Preservation Methods Differ in Fecal Microbiome Stability, Affecting Suitability for Field Studies | MSystems | 2016 | 392 |
| 45 | Insights from genomes into the evolutionary importance and prevalence of hybridization in nature | Nature Ecology and Evolution | 2019 | 390 |
| 46 | Caterpillars lack a resident gut microbiome | Proceedings of the National Academy of Sciences of the United States of America | 2017 | 379 |
| 47 | The Macaque Gut Microbiome in Health, Lentiviral Infection, and Chronic Enterocolitis | PLoS Pathogens | 2008 | 377 |
| 48 | Ecoenzymatic stoichiometry of microbial nutrient acquisition in tropical soils | Biogeochemistry | 2014 | 376 |
| 49 | A 5-bp deletion in ELOVL4 is associated with two related forms of autosomal dominant macular dystrophy | Nature Genetics | 2001 | 374 |
| 50 | A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans | Nature Genetics | 2005 | 366 |
