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Top Articles

#TitleJournalYearCitations
1RIG-I, MDA5 and TLR3 Synergistically Play an Important Role in Restriction of Dengue Virus InfectionPLoS Neglected Tropical Diseases2011258
2Biocompatible, Uniform, and Redispersible Mesoporous Silica Nanoparticles for Cancer‐Targeted Drug Delivery In VivoAdvanced Functional Materials2014238
3Lipid rafts are involved in SARS-CoV entry into Vero E6 cellsBiochemical and Biophysical Research Communications2008221
4The molecular functions of hepatocyte nuclear factors – In and beyond the liverJournal of Hepatology2018175
5Single-cell multimodal profiling reveals cellular epigenetic heterogeneityNature Methods2016158
6Biochemical and functional characterization of the membrane association and membrane permeabilizing activity of the severe acute respiratory syndrome coronavirus envelope proteinVirology2006127
7N6-Methyladenosine: a conformational marker that regulates the substrate specificity of human demethylases FTO and ALKBH5Scientific Reports2016118
8Convalescent COVID-19 patients are susceptible to endothelial dysfunction due to persistent immune activationELife2021113
9Klf2 Is an Essential Factor that Sustains Ground State PluripotencyCell Stem Cell2014111
10Culturing Fibroblasts in 3D Human Hair Keratin HydrogelsACS Applied Materials & Interfaces201596
11The Cellular RNA Helicase DDX1 Interacts with Coronavirus Nonstructural Protein 14 and Enhances Viral ReplicationJournal of Virology201095
12Cell cycle arrest and apoptosis induced by the coronavirus infectious bronchitis virus in the absence of p53Virology200790
13Angiopoietin-like 4 Stimulates STAT3-mediated iNOS Expression and Enhances Angiogenesis to Accelerate Wound Healing in Diabetic MiceMolecular Therapy201489
14A role for sorting nexin 27 in AMPA receptor traffickingNature Communications201489
15Sumoylation of the nucleocapsid protein of severe acute respiratory syndrome coronavirusFEBS Letters200585
16Inhibition of Protein Kinase R Activation and Upregulation of GADD34 Expression Play a Synergistic Role in Facilitating Coronavirus Replication by Maintaining De Novo Protein Synthesis in Virus-Infected CellsJournal of Virology200985
17A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor of N6-methyladenosine demethylase FTOChemical Science201585
18Ribosome protection by antibiotic resistance ATP-binding cassette proteinProceedings of the National Academy of Sciences of the United States of America201883
19Expression of SARS-coronavirus envelope protein in Escherichia coli cells alters membrane permeabilityBiochemical and Biophysical Research Communications200482
20The Transmembrane Oligomers of Coronavirus Protein EBiophysical Journal200581
21Control of muscle fibre-type diversity during embryonic development: The zebrafish paradigmMechanisms of Development201380
22Natural IgG antibodies provide innate protection against ficolin-opsonized bacteriaEMBO Journal201377
23Graded Control of Climbing-Fiber-Mediated Plasticity and Learning by Inhibition in the CerebellumNeuron201874
24Supramolecular nanoparticle carriers self-assembled from cyclodextrin- and adamantane-functionalized polyacrylates for tumor-targeted drug deliveryJournal of Materials Chemistry B201473
25Polymer-Enriched 3D Graphene Foams for Biomedical ApplicationsACS Applied Materials & Interfaces201573
26An arginine-to-proline mutation in a domain with undefined functions within the helicase protein (Nsp13) is lethal to the coronavirus infectious bronchitis virus in cultured cellsVirology200772
27Cell cycle inhibitors protect motor neurons in an organoid model of Spinal Muscular AtrophyCell Death and Disease201872
28Human and mouse monocytes display distinct signalling and cytokine profiles upon stimulation with FFAR2/FFAR3 short-chain fatty acid receptor agonistsScientific Reports201669
29Surface Enhanced Raman Spectroscopy Based Biosensor with a Microneedle Array for Minimally Invasive In Vivo Glucose MeasurementsACS Sensors202069
30The cerebellum linearly encodes whisker position during voluntary movementELife201669
31T-cell death following immune activation is mediated by mitochondria-localized SARMCell Death and Differentiation201367
32A STAT3-based gene signature stratifies glioma patients for targeted therapyNature Communications201967
33Stroke biomarkers in clinical practice: A critical appraisalNeurochemistry International201763
34Single-nucleotide-resolution sequencing of humanN6-methyldeoxyadenosine reveals strand-asymmetric clusters associated with SSBP1 on the mitochondrial genomeNucleic Acids Research201862
35Structural insights into the LCIB protein family reveals a new group of β-carbonic anhydrasesProceedings of the National Academy of Sciences of the United States of America201661
36Structural Basis of the PNRC2-Mediated Link between mRNA Surveillance and DecappingStructure201259
37Angiopoietin-like 4 Increases Pulmonary Tissue Leakiness and Damage during Influenza PneumoniaCell Reports201559
38Biochemical evidence for the presence of mixed membrane topologies of the severe acute respiratory syndrome coronavirus envelope protein expressed in mammalian cellsFEBS Letters200658
39Anti‐cAngptl4 Ab‐Conjugated N‐TiO2/NaYF4:Yb,Tm Nanocomposite for Near Infrared‐Triggered Drug Release and Enhanced Targeted Cancer Cell AblationAdvanced Healthcare Materials201254
40A 3D Biomimetic Model of Tissue Stiffness Interface for Cancer Drug TestingMolecular Pharmaceutics201453
41Proteolytic processing of polyproteins 1a and 1ab between non-structural proteins 10 and 11/12 of Coronavirus infectious bronchitis virus is dispensable for viral replication in cultured cellsVirology200852
42Parallel bimodal single-cell sequencing of transcriptome and chromatin accessibilityGenome Research202052
43Coronavirus envelope protein: A small membrane protein with multiple functionsCellular and Molecular Life Sciences200751
44Bio-inspired micropatterned hydrogel to direct and deconstruct hierarchical processing of geometry-force signals by human mesenchymal stem cells during smooth muscle cell differentiationNPG Asia Materials201551
45Interaction of the Coronavirus Infectious Bronchitis Virus Membrane Protein with β-Actin and Its Implication in Virion Assembly and BuddingPLoS ONE200949
46SMAD3 Deficiency Promotes Inflammatory Aortic Aneurysms in Angiotensin II–Infused Mice Via Activation of iNOSJournal of the American Heart Association201348
47Stress sensor Ire1 deploys a divergent transcriptional program in response to lipid bilayer stressJournal of Cell Biology202048
48Early controlled release of peroxisome proliferator-activated receptor β/δ agonist GW501516 improves diabetic wound healing through redox modulation of wound microenvironmentJournal of Controlled Release201547
49Recellularization of decellularized adipose tissue-derived stem cells: role of the cell-secreted extracellular matrix in cellular differentiationBiomaterials Science201844
50Dopamine D2 receptor-mediated circuit from the central amygdala to the bed nucleus of the stria terminalis regulates impulsive behaviorProceedings of the National Academy of Sciences of the United States of America201844