# | Title | Journal | Year | Citations |
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1 | Regulation of innate immune cell function by mTOR | Nature Reviews Immunology | 2015 | 612 |
2 | In vitro cell migration and invasion assays | Mutation Research - Reviews in Mutation Research | 2013 | 605 |
3 | mTOR as Regulator of Lifespan, Aging, and Cellular Senescence: A Mini-Review | Gerontology | 2018 | 326 |
4 | Comparison of cancer cells cultured in 2D vs 3D reveals differences in AKT/mTOR/S6-kinase signaling and drug response | Journal of Cell Science | 2017 | 308 |
5 | The role of the placenta in fetal exposure to heavy metals | Wiener Medizinische Wochenschrift | 2012 | 206 |
6 | mTORC1 and mTORC2 as regulators of cell metabolism in immunity | FEBS Letters | 2017 | 194 |
7 | Chronic signaling via the metabolic checkpoint kinase mTORC1 induces macrophage granuloma formation and marks sarcoidosis progression | Nature Immunology | 2017 | 191 |
8 | Cancer-associated fibroblast-derived WNT2 increases tumor angiogenesis in colon cancer | Angiogenesis | 2020 | 174 |
9 | Perinatal lead and mercury exposure in Austria | Science of the Total Environment | 2010 | 143 |
10 | Monogenic variants in dystonia: an exome-wide sequencing study | Lancet Neurology, The | 2020 | 139 |
11 | STAT3 regulated ARF expression suppresses prostate cancer metastasis | Nature Communications | 2015 | 136 |
12 | Modeling human carcinomas: Physiologically relevant 3D models to improve anti-cancer drug development | Advanced Drug Delivery Reviews | 2014 | 129 |
13 | Albumin is the major carrier protein for PFOS, PFOA, PFHxS, PFNA and PFDA in human plasma | Environment International | 2020 | 123 |
14 | Inhibition of mTOR blocks the anti-inflammatory effects of glucocorticoids in myeloid immune cells | Blood | 2011 | 121 |
15 | The relevance of the individual genetic background for the toxicokinetics of two significant neurodevelopmental toxicants: Mercury and lead | Mutation Research - Reviews in Mutation Research | 2010 | 115 |
16 | PDGFR blockade is a rational and effective therapy for NPM-ALK–driven lymphomas | Nature Medicine | 2012 | 113 |
17 | Merging high-quality biochemical fractionation with a refined flow cytometry approach to monitor nucleocytoplasmic protein expression throughout the unperturbed mammalian cell cycle | Nature Protocols | 2013 | 113 |
18 | Autocrine WNT2 signaling in fibroblasts promotes colorectal cancer progression | Oncogene | 2017 | 107 |
19 | IGFBP7, a novel tumor stroma marker, with growth-promoting effects in colon cancer through a paracrine tumor–stroma interaction | Oncogene | 2015 | 98 |
20 | Effects of Interferons and Viruses on Metabolism | Frontiers in Immunology | 2016 | 96 |
21 | mTOR-Mediated Regulation of Dendritic Cell Differentiation and Function | Trends in Immunology | 2016 | 93 |
22 | De Novo Mutations in SON Disrupt RNA Splicing of Genes Essential for Brain Development and Metabolism, Causing an Intellectual-Disability Syndrome | American Journal of Human Genetics | 2016 | 81 |
23 | Nucleocytoplasmic localization of p70 S6K1, but not of its isoforms p85 and p31, is regulated by TSC2/mTOR | Oncogene | 2011 | 79 |
24 | Immune responses of macrophages and dendritic cells regulated by mTOR signalling | Biochemical Society Transactions | 2013 | 72 |
25 | Contribution of human amniotic fluid stem cells to renal tissue formation depends on mTOR | Human Molecular Genetics | 2010 | 70 |
26 | The Resazurin Reduction Assay Can Distinguish Cytotoxic from Cytostatic Compounds in Spheroid Screening Assays | Journal of Biomolecular Screening | 2014 | 70 |
27 | Loss of miR-200 family in 5-fluorouracil resistant colon cancer drives lymphendothelial invasiveness in vitro | Human Molecular Genetics | 2015 | 70 |
28 | The HDL receptor SR-BI is associated with human prostate cancer progression and plays a possible role in establishing androgen independence | Reproductive Biology and Endocrinology | 2015 | 67 |
29 | Stromal-derived IGF2 promotes colon cancer progression via paracrine and autocrine mechanisms | Oncogene | 2017 | 63 |
30 | mTOR Senses Environmental Cues to Shape the Fibroblast-like Synoviocyte Response to Inflammation | Cell Reports | 2018 | 62 |
31 | Increased complexity in carcinomas: Analyzing and modeling the interaction of human cancer cells with their microenvironment | Seminars in Cancer Biology | 2015 | 60 |
32 | Exclusion from spheroid formation identifies loss of essential cell-cell adhesion molecules in colon cancer cells | Scientific Reports | 2018 | 59 |
33 | Sarcoidosis and the mTOR, Rac1, and Autophagy Triad | Trends in Immunology | 2020 | 59 |
34 | Applications of Amniotic Membrane and Fluid in Stem Cell Biology and Regenerative Medicine | Stem Cells International | 2012 | 58 |
35 | STAT5BN642H is a driver mutation for T cell neoplasia | Journal of Clinical Investigation | 2017 | 57 |
36 | Quantification of HDL Proteins, Cardiac Events, and Mortality in Patients with Type 2 Diabetes on Hemodialysis | Clinical Journal of the American Society of Nephrology: CJASN | 2015 | 54 |
37 | Metabolic Programming of Macrophages: Implications in the Pathogenesis of Granulomatous Disease | Frontiers in Immunology | 2019 | 53 |
38 | Inverse Data-Driven Modeling and Multiomics Analysis Reveals Phgdh as a Metabolic Checkpoint of Macrophage Polarization and Proliferation | Cell Reports | 2020 | 52 |
39 | Sequential combination of azacitidine and lenalidomide in del(5q) higher-risk myelodysplastic syndromes or acute myeloid leukemia: a phase I study | Leukemia | 2013 | 50 |
40 | Lead (Pb) and neurodevelopment: A review on exposure and biomarkers of effect (BDNF, HDL) and susceptibility | International Journal of Hygiene and Environmental Health | 2021 | 50 |
41 | Efficacy and safety of Everolimus in children with TSC - associated epilepsy – Pilot data from an open single-center prospective study | Orphanet Journal of Rare Diseases | 2016 | 47 |
42 | A New Immunomodulatory Role for Peroxisomes in Macrophages Activated by the TLR4 Ligand Lipopolysaccharide | Journal of Immunology | 2017 | 45 |
43 | HDL Cholesterol Efflux Does Not Predict Cardiovascular Risk in Hemodialysis Patients | Journal of the American Society of Nephrology: JASN | 2017 | 45 |
44 | Bay11-7082 inhibits the disintegration of the lymphendothelial barrier triggered by MCF-7 breast cancer spheroids; the role of ICAM-1 and adhesion | British Journal of Cancer | 2013 | 44 |
45 | Three-dimensional and co-culture models for preclinical evaluation of metal-based anticancer drugs | Investigational New Drugs | 2015 | 44 |
46 | Mercury toxicokinetics of the healthy human term placenta involve amino acid transporters and ABC transporters | Toxicology | 2016 | 44 |
47 | p70 S6K1 nuclear localization depends on its mTOR-mediated phosphorylation at T389, but not on its kinase activity towards S6 | Amino Acids | 2012 | 43 |
48 | Exome sequencing and pathogenicity-network analysis of five French families implicate mTOR signalling and autophagy in familial sarcoidosis | European Respiratory Journal | 2019 | 43 |
49 | Current Insights in Genetics of Sarcoidosis: Functional and Clinical Impacts | Journal of Clinical Medicine | 2020 | 43 |
50 | STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pathway | Oncogene | 2021 | 42 |