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Department of Molecular Biology
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top-articles
Department of Molecular Biology
209
(top 1%)
papers
11.7K
(top 1%)
citations
61
(top 1%)
h
-index
102
(top 1%)
g
-index
215
all documents
12.4K
doc citations
1.8K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
Host defense against Pseudomonas aeruginosa requires ceramide-rich membrane rafts
Nature Medicine
2003
521
2
Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis
Nature Medicine
2008
501
3
Raft ceramide in molecular medicine
Oncogene
2003
392
4
Acid sphingomyelinase–ceramide system mediates effects of antidepressant drugs
Nature Medicine
2013
313
5
Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): A Novel Pharmacological Group of Drugs with Broad Clinical Applications
Cellular Physiology and Biochemistry
2010
299
6
Ceramide-enriched membrane domains
Biochimica Et Biophysica Acta - Molecular Cell Research
2005
282
7
Ceramide-mediated clustering is required for CD95-DISC formation
Oncogene
2003
258
8
Eryptosis, a Window to Systemic Disease
Cellular Physiology and Biochemistry
2008
228
9
Brain membrane lipids in major depression and anxiety disorders
Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids
2015
222
10
Ceramide-enriched membrane domains—Structure and function
Biochimica Et Biophysica Acta - Biomembranes
2009
212
11
Physiological and pathophysiological aspects of ceramide
American Journal of Physiology - Regulatory Integrative and Comparative Physiology
2006
202
12
Rhinoviruses Infect Human Epithelial Cells via Ceramide-enriched Membrane Platforms
Journal of Biological Chemistry
2005
195
13
Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes
Proceedings of the National Academy of Sciences of the United States of America
2008
194
14
A Novel Potassium Channel in Lymphocyte Mitochondria
Journal of Biological Chemistry
2005
188
15
Cell Volume Regulatory Ion Channels in Cell Proliferation and Cell Death
Methods in Enzymology
2007
174
16
Antidepressants act by inducing autophagy controlled by sphingomyelin–ceramide
Molecular Psychiatry
2018
166
17
TRAIL activates acid sphingomyelinase via a redox mechanism and releases ceramide to trigger apoptosis
Oncogene
2006
160
18
Ceramide, membrane rafts and infections
Journal of Molecular Medicine
2004
153
19
Acid Sphingomyelinase Inhibitors Normalize Pulmonary Ceramide and Inflammation in Cystic Fibrosis
American Journal of Respiratory Cell and Molecular Biology
2010
153
20
Identification of Novel Functional Inhibitors of Acid Sphingomyelinase
PLoS ONE
2011
145
21
A polyphenol rich plant extract, CYSTUS052, exerts anti influenza virus activity in cell culture without toxic side effects or the tendency to induce viral resistance
Antiviral Research
2007
142
22
Conjugated bilirubin triggers anemia by inducing erythrocyte death
Hepatology
2015
141
23
Direct Pharmacological Targeting of a Mitochondrial Ion Channel Selectively Kills Tumor Cells In Vivo
Cancer Cell
2017
138
24
Inhibitors of mitochondrial Kv1.3 channels induce Bax/Bak‐independent death of cancer cells
EMBO Molecular Medicine
2012
136
25
Role of Mitochondria in Apoptosis
Experimental Physiology
2003
135
26
Regulation of death receptor signaling and apoptosis by ceramide
Pharmacological Research
2003
133
27
Ceramide and cell death receptor clustering
Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids
2002
132
28
Membrane rafts in host–pathogen interactions
Biochimica Et Biophysica Acta - Biomembranes
2006
131
29
Pseudomonas aeruginosa
Pyocyanin Induces Neutrophil Death
via
Mitochondrial Reactive Oxygen Species and Mitochondrial Acid Sphingomyelinase
Antioxidants and Redox Signaling
2015
122
30
Mitochondrial Ceramide-Rich Macrodomains Functionalize Bax upon Irradiation
PLoS ONE
2011
122
31
Interclonal gradient of virulence in the
P
seudomonas aeruginosa
pangenome from disease and environment
Environmental Microbiology
2015
113
32
Ceramide-induced cell death in malignant cells
Cancer Letters
2008
112
33
Sphingoid long chain bases prevent lung infection by
Pseudomonas aeruginosa
EMBO Molecular Medicine
2014
109
34
Acid Sphingomyelinase and Its Redox Amplification in Formation of Lipid Raft Redox Signaling Platforms in Endothelial Cells
Antioxidants and Redox Signaling
2007
107
35
Alveolar inflammation in cystic fibrosis
Journal of Cystic Fibrosis
2010
103
36
Inhibition of acid sphingomyelinase by tricyclic antidepressants and analogons
Frontiers in Physiology
2014
103
37
Endothelial Nlrp3 inflammasome activation associated with lysosomal destabilization during coronary arteritis
Biochimica Et Biophysica Acta - Molecular Cell Research
2015
102
38
Ceramide inhibits the potassium channel Kv1.3 by the formation of membrane platforms
Biochemical and Biophysical Research Communications
2003
101
39
Activation of Nlrp3 Inflammasomes Enhances Macrophage Lipid-Deposition and Migration: Implication of a Novel Role of Inflammasome in Atherogenesis
PLoS ONE
2014
100
40
The ceramide system as a novel antidepressant target
Trends in Pharmacological Sciences
2014
96
41
Enhancement of endothelial permeability by free fatty acid through lysosomal cathepsin B-mediated Nlrp3 inflammasome activation
Oncotarget
2016
95
42
Cationic cell-penetrating peptides induce ceramide formation via acid sphingomyelinase: Implications for uptake
Journal of Controlled Release
2010
92
43
Alterations in Ceramide Concentration and pH Determine the Release of Reactive Oxygen Species by
Cftr
-Deficient Macrophages on Infection
Journal of Immunology
2010
90
44
β1-Integrin Accumulates in Cystic Fibrosis Luminal Airway Epithelial Membranes and Decreases Sphingosine, Promoting Bacterial Infections
Cell Host and Microbe
2017
86
45
Ceramide in Redox Signaling and Cardiovascular Diseases
Cellular Physiology and Biochemistry
2010
85
46
Regulation of hematogenous tumor metastasis by acid sphingomyelinase
EMBO Molecular Medicine
2015
83
47
Pharmacological targeting of ion channels for cancer therapy: In vivo evidences
Biochimica Et Biophysica Acta - Molecular Cell Research
2016
82
48
Mitochondrial ion channels as oncological targets
Oncogene
2014
81
49
Clofazimine, Psora-4 and PAP-1, inhibitors of the potassium channel Kv1.3, as a new and selective therapeutic strategy in chronic lymphocytic leukemia
Leukemia
2013
75
50
Modulation of the Voltage-Gated Potassium Channel Kv1.5 by the SGK1 Protein Kinase Involves Inhibition of Channel Ubiquitination
Cellular Physiology and Biochemistry
2008
74
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