avg. Impact Factor

Most Cited Articles of Department of Biochemistry and Molecular Biology

STRING 8--a global view on proteins and their functional interactions in 630 organismsNucleic Acids Research20091.8K
Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neuronsProceedings of the National Academy of Sciences of the United States of America19981.1K
DELLY: structural variant discovery by integrated paired-end and split-read analysisBioinformatics20121K
Variation in transcription factor binding among humansScience2010444
Gene transfer from bacteria and archaea facilitated evolution of an extremophilic eukaryoteScience2013316
Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family membersProceedings of the National Academy of Sciences of the United States of America1998308
The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substratesRna2000267
Single-cell epigenomics: Recording the past and predicting the futureScience2017232
Understanding transport by the major facilitator superfamily (MFS): structures pave the wayNature Reviews Molecular Cell Biology2016207
Ribosome-mediated translational pause and protein domain organizationProtein Science1996202
Regulation of mA Transcripts by the 3'→5' RNA Helicase YTHDC2 Is Essential for a Successful Meiotic Program in the Mammalian GermlineMolecular Cell2017201
General anesthesia selectively disrupts astrocyte calcium signaling in the awake mouse cortexProceedings of the National Academy of Sciences of the United States of America2012184
Participation of the nuclear cap binding complex in pre-mRNA 3' processingProceedings of the National Academy of Sciences of the United States of America1997182
Modeling studies of the change in conformation required for cleavage of limited proteolytic sitesProtein Science1994174
SomaticSignatures: inferring mutational signatures from single-nucleotide variantsBioinformatics2015171
A method for localizing ligand binding pockets in protein structuresProteins: Structure, Function and Bioinformatics2006160
Structural principles of alpha/beta barrel proteins: the packing of the interior of the sheetProteins: Structure, Function and Bioinformatics1989143
Domain conformation of tau protein studied by solution small-angle X-ray scatteringBiochemistry2008142
Making proteins in the powerhouseCell Metabolism2014139
A Drosophila melanogaster homologue of Caenorhabditis elegans par-1 acts at an early step in embryonic-axis formationNature Cell Biology2000135
Structural basis of histone H2A-H2B recognition by the essential chaperone FACTNature2013131
Trapping cDNAs encoding secreted proteins from the salivary glands of the malaria vector Anopheles gambiaeProceedings of the National Academy of Sciences of the United States of America1999131
Protein secondary structural types are differentially coded on messenger RNAProtein Science1996131
Identification of proteins in polyacrylamide gels by mass spectrometric peptide mapping combined with database searchBiological Mass Spectrometry1994130
Structures and characterization of digoxin- and bufalin-bound Na+,K+-ATPase compared with the ouabain-bound complexProceedings of the National Academy of Sciences of the United States of America2015129