| # | Title | Journal | Year | Citations |
|---|
| 1 | Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2016 for the treatment of colorectal cancer | International Journal of Clinical Oncology | 2018 | 1,187 |
| 2 | Epidemiology of hypertensive disorders in pregnancy: prevalence, risk factors, predictors and prognosis | Hypertension Research | 2017 | 327 |
| 3 | Vascular Mechanobiology Endothelial Cell Responses to Fluid Shear Stress | Circulation Journal | 2009 | 318 |
| 4 | Flow detection and calcium signalling in vascular endothelial cells | Cardiovascular Research | 2013 | 172 |
| 5 | Effects of Shear Stress and Stretch on Endothelial Function | Antioxidants and Redox Signaling | 2011 | 164 |
| 6 | Loss-of-function mutations of CHST14 in a new type of Ehlers-Danlos syndrome | Human Mutation | 2010 | 137 |
| 7 | A Functional SNP in BNC2 Is Associated with Adolescent Idiopathic Scoliosis | American Journal of Human Genetics | 2015 | 119 |
| 8 | Visualization of flow-induced ATP release and triggering of Ca2+ waves at caveolae in vascular endothelial cells | Journal of Cell Science | 2011 | 116 |
| 9 | Characterization of the interactions between Escherichia coli receptors, LPS and OmpC, and bacteriophage T4 long tail fibers | MicrobiologyOpen | 2016 | 88 |
| 10 | Endothelial cell and model membranes respond to shear stress by rapidly decreasing the order of their lipid phases | Journal of Cell Science | 2013 | 84 |
| 11 | Association Between Eating Speed and Metabolic Syndrome in a Three-Year Population-Based Cohort Study | Journal of Epidemiology | 2015 | 78 |
| 12 | Rho GTP exchange factor ARHGEF11 regulates the integrity of epithelial junctions by connecting ZO-1 and RhoA-Myosin II signaling | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 74 |
| 13 | Fluid shear stress induces differentiation of circulating phenotype endothelial progenitor cells | American Journal of Physiology - Cell Physiology | 2012 | 73 |
| 14 | Japanese guideline for the treatment of idiopathic pulmonary fibrosis | Respiratory Investigation | 2018 | 72 |
| 15 | Melatonin-enhanced hyperactivation of hamster sperm | Reproduction | 2008 | 66 |
| 16 | Relevance of substantia nigra hyperechogenicity and reduced odor identification in idiopathic REM sleep behavior disorder | Sleep Medicine | 2010 | 65 |
| 17 | Prevalence of perinatal depression among Japanese women: a meta-analysis | Annals of General Psychiatry | 2020 | 65 |
| 18 | LC-ESI/MS/MS analysis of neonicotinoids in urine of very low birth weight infants at birth | PLoS ONE | 2019 | 64 |
| 19 | Facilitatory Actions of Serotonin Type 3 Receptors on GABAergic Inhibitory Synaptic Transmission in the Spinal Superficial Dorsal Horn | Journal of Neurophysiology | 2009 | 63 |
| 20 | Botulinum toxin B in the sensory afferent: Transmitter release, spinal activation, and pain behavior | Pain | 2014 | 62 |
| 21 | The Dose-Response Relationship Between Body Mass Index and the Risk of Incident Stage ^|^ge;3 Chronic Kidney Disease in a General Japanese Population: The Ibaraki Prefectural Health Study (IPHS) | Journal of Epidemiology | 2014 | 62 |
| 22 | Shear stress augments mitochondrial ATP generation that triggers ATP release and Ca2+signaling in vascular endothelial cells | American Journal of Physiology - Heart and Circulatory Physiology | 2018 | 62 |
| 23 | Olfactory dysfunction in idiopathic REM sleep behavior disorder | Sleep Medicine | 2010 | 58 |
| 24 | NMDA receptor 2B subunit-mediated synaptic transmission in the superficial dorsal horn of peripheral nerve-injured neuropathic mice | Brain Research | 2007 | 57 |
| 25 | Proteasome inhibitors exert cytotoxicity and increase chemosensitivity via transcriptional repression of Notch1 in T-cell acute lymphoblastic leukemia | Leukemia | 2014 | 55 |
| 26 | Phase Angle as an Indicator of Sarcopenia, Malnutrition, and Cachexia in Inpatients with Cardiovascular Diseases | Journal of Clinical Medicine | 2020 | 54 |
| 27 | A new Ehlers–Danlos syndrome with craniofacial characteristics, multiple congenital contractures, progressive joint and skin laxity, and multisystem fragility‐related manifestations | American Journal of Medical Genetics, Part A | 2010 | 53 |
| 28 | Serotonin-enhanced hyperactivation of hamster sperm | Reproduction | 2011 | 52 |
| 29 | Regulation of Spinal Substance P Release by Intrathecal Calcium Channel Blockade | Anesthesiology | 2011 | 51 |
| 30 | Inhibition of l-type amino acid transporter 1 activity as a new therapeutic target for cholangiocarcinoma treatment | Tumor Biology | 2017 | 50 |
| 31 | The Structural and Functional Organization of the Podocyte Filtration Slits Is Regulated by Tjp1/ZO-1 | PLoS ONE | 2014 | 49 |
| 32 | An ADP‐ribosyltransferase Alt of bacteriophage T4 negatively regulates the Escherichia coli MazF toxin of a toxin–antitoxin module | Molecular Microbiology | 2016 | 49 |
| 33 | Fungi can be a useful forensic tool | Legal Medicine | 2006 | 48 |
| 34 | Influence of Post-disaster Evacuation on Incidence of Metabolic Syndrome | Journal of Atherosclerosis and Thrombosis | 2017 | 48 |
| 35 | Vascular endothelial cell membranes differentiate between stretch and shear stress through transitions in their lipid phases | American Journal of Physiology - Heart and Circulatory Physiology | 2015 | 47 |
| 36 | Prevalence and risk factors for low back pain among professional cooks working in school lunch services | BMC Public Health | 2007 | 45 |
| 37 | New Molecular Mechanisms for Cardiovascular Disease: Blood Flow Sensing Mechanism in Vascular Endothelial Cells | Journal of Pharmacological Sciences | 2011 | 44 |
| 38 | Shear stress activates mitochondrial oxidative phosphorylation by reducing plasma membrane cholesterol in vascular endothelial cells | Proceedings of the National Academy of Sciences of the United States of America | 2020 | 44 |
| 39 | Computed tomographic features of the bony canal of the cochlear nerve in pediatric patients with unilateral sensorineural hearing loss | Radiation Medicine | 2008 | 41 |
| 40 | Prevalence and Risk Factors of Low Back Pain among Thai and Myanmar Migrant Seafood Processing Factory Workers in Samut Sakorn Province, Thailand | Industrial Health | 2010 | 40 |
| 41 | Prokaryotic toxin–antitoxin systems: novel regulations of the toxins | Current Genetics | 2016 | 39 |
| 42 | Executive summary of the Clinical Guidelines of Pharmacotherapy for Neuropathic Pain: second edition by the Japanese Society of Pain Clinicians | Journal of Anesthesia | 2018 | 38 |
| 43 | Growth Differentiation Factor-15 (GDF-15) is a Biomarker of Muscle Wasting and Renal Dysfunction in Preoperative Cardiovascular Surgery Patients | Journal of Clinical Medicine | 2019 | 36 |
| 44 | Childhood obesity: rapid weight gain in early childhood and subsequent cardiometabolic risk | Clinical Pediatric Endocrinology | 2020 | 36 |
| 45 | E2f1-deficient NOD/SCID mice have dry mouth due to a change of acinar/duct structure and the down-regulation of AQP5 in the salivary gland | Pflugers Archiv European Journal of Physiology | 2013 | 34 |
| 46 | Hospital Safety Climate, Psychosocial Risk Factors and Needlestick Injuries in Japan | Industrial Health | 2010 | 33 |
| 47 | Lung Cancer in Chronic Interstitial Pneumonia: Early Manifestation From Serial CT Observations | American Journal of Roentgenology | 2012 | 33 |
| 48 | Muscular dystrophy with large mitochondria associated with mutations in the CHKB gene in three British patients: Extending the clinical and pathological phenotype | Neuromuscular Disorders | 2013 | 33 |
| 49 | Transplantation for juvenile myelomonocytic leukemia: a retrospective study of 30 children treated with a regimen of busulfan, fludarabine, and melphalan | International Journal of Hematology | 2015 | 33 |
| 50 | Nuclear medicine practice in Japan: a report of the eighth nationwide survey in 2017 | Annals of Nuclear Medicine | 2019 | 33 |
