| # | Title | Journal | Year | Citations |
|---|
| 1 | Glucose Uptake and Runx2 Synergize to Orchestrate Osteoblast Differentiation and Bone Formation | Cell | 2015 | 351 |
| 2 | Extra-Renal Elimination of Uric Acid via Intestinal Efflux Transporter BCRP/ABCG2 | PLoS ONE | 2012 | 189 |
| 3 | Oral drug delivery utilizing intestinal OATP transporters | Advanced Drug Delivery Reviews | 2012 | 144 |
| 4 | Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes | Annals of the Rheumatic Diseases | 2016 | 144 |
| 5 | Potentially inappropriate medication use in elderly Japanese patients | American Journal of Geriatric Pharmacotherapy | 2010 | 133 |
| 6 | Species Difference in the Effect of Grapefruit Juice on Intestinal Absorption of Talinolol between Human and Rat | Journal of Pharmacology and Experimental Therapeutics | 2010 | 121 |
| 7 | Solute Carrier Transporters as Targets for Drug Delivery and Pharmacological Intervention for Chemotherapy | Journal of Pharmaceutical Sciences | 2011 | 108 |
| 8 | Genetic Polymorphisms of OATP Transporters and Their Impact on Intestinal Absorption and Hepatic Disposition of Drugs | Drug Metabolism and Pharmacokinetics | 2012 | 102 |
| 9 | Environmental Behaviors and Toxicities of Polycyclic Aromatic Hydrocarbons and Nitropolycyclic Aromatic Hydrocarbons | Chemical and Pharmaceutical Bulletin | 2016 | 88 |
| 10 | Concentration-Dependent Effect of Naringin on Intestinal Absorption of β1-Adrenoceptor Antagonist Talinolol Mediated by P-Glycoprotein and Organic Anion Transporting Polypeptide (Oatp) | Pharmaceutical Research | 2009 | 86 |
| 11 | Transport of Ipratropium, an Anti-Chronic Obstructive Pulmonary Disease Drug, Is Mediated by Organic Cation/Carnitine Transporters in Human Bronchial Epithelial Cells: Implications for Carrier-Mediated Pulmonary Absorption | Molecular Pharmaceutics | 2010 | 86 |
| 12 | Model Analysis of the Concentration-Dependent Permeability of P-gp Substrates | Pharmaceutical Research | 2010 | 85 |
| 13 | 3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents | Journal of Medicinal Chemistry | 2022 | 75 |
| 14 | Intestinal Absorption of HMG-CoA Reductase Inhibitor Pravastatin Mediated by Organic Anion Transporting Polypeptide | Pharmaceutical Research | 2010 | 69 |
| 15 | Renal Secretion of Uric Acid by Organic Anion Transporter 2 (OAT2/SLC22A7) in Human | Biological and Pharmaceutical Bulletin | 2010 | 68 |
| 16 | Interaction of Drug or Food with Drug Transporters in Intestine and Liver | Current Drug Metabolism | 2015 | 68 |
| 17 | Differential Effect of Grapefruit Juice on Intestinal Absorption of Statins Due to Inhibition of Organic Anion Transporting Polypeptide and/or P-glycoprotein | Journal of Pharmaceutical Sciences | 2011 | 64 |
| 18 | Synthetic biology based construction of biological activity-related library of fungal decalin-containing diterpenoid pyrones | Nature Communications | 2020 | 64 |
| 19 | Food‐derived hydrophilic antioxidant ergothioneine is distributed to the brain and exerts antidepressant effect in mice | Brain and Behavior | 2016 | 63 |
| 20 | Functional Pleiotropy of Organic Anion Transporting Polypeptide OATP2B1 Due to Multiple Binding Sites | Drug Metabolism and Pharmacokinetics | 2012 | 61 |
| 21 | Involvement of Carnitine/Organic Cation Transporter OCTN1/SLC22A4 in Gastrointestinal Absorption of Metformin | Journal of Pharmaceutical Sciences | 2013 | 60 |
| 22 | Functional expression of carnitine/organic cation transporter OCTN1 in mouse brain neurons: Possible involvement in neuronal differentiation | Neurochemistry International | 2012 | 57 |
| 23 | Major Active Components in Grapefruit, Orange, and Apple Juices Responsible for OATP2B1-Mediated Drug Interactions | Journal of Pharmaceutical Sciences | 2013 | 57 |
| 24 | Intestinal Absorption of HMG-CoA Reductase Inhibitor Pitavastatin Mediated by Organic Anion Transporting Polypeptide and P-Glycoprotein/Multidrug Resistance 1 | Drug Metabolism and Pharmacokinetics | 2011 | 56 |
| 25 | Major Active Components in Grapefruit, Orange, and Apple Juices Responsible for OATP2B1-Mediated Drug Interactions | Journal of Pharmaceutical Sciences | 2013 | 55 |
| 26 | Dipeptide species regulate p38MAPK–Smad3 signalling to maintain chronic myelogenous leukaemia stem cells | Nature Communications | 2015 | 52 |
| 27 | Involvement of Choline Transporter-Like Proteins, CTL1 and CTL2, in Glucocorticoid-Induced Acceleration of Phosphatidylcholine Synthesis via Increased Choline Uptake | Biological and Pharmaceutical Bulletin | 2010 | 51 |
| 28 | Long-Lasting Inhibitory Effect of Apple and Orange Juices, but Not Grapefruit Juice, on OATP2B1-Mediated Drug Absorption | Drug Metabolism and Disposition | 2013 | 51 |
| 29 | A common missense variant of monocarboxylate transporter 9 (MCT9/SLC16A9) gene is associated with renal overload gout, but not with all gout susceptibility | Human Cell | 2013 | 48 |
| 30 | Direct Inhibition and Down-regulation by Uremic Plasma Components of Hepatic Uptake Transporter for SN-38, an Active Metabolite of Irinotecan, in Humans | Pharmaceutical Research | 2014 | 48 |
| 31 | Functional Characterization of Ergothioneine Transport by Rat Organic Cation/Carnitine Transporter Octn1 (slc22a4) | Biological and Pharmaceutical Bulletin | 2008 | 46 |
| 32 | Nucleotide Excision Repair-dependent DNA Double-strand Break Formation and ATM Signaling Activation in Mammalian Quiescent Cells | Journal of Biological Chemistry | 2014 | 45 |
| 33 | Active intestinal absorption of fluoroquinolone antibacterial agent ciprofloxacin by organic anion transporting polypeptide, Oatp1a5 | Biopharmaceutics and Drug Disposition | 2012 | 44 |
| 34 | PDZK1 Regulates Breast Cancer Resistance Protein in Small Intestine | Drug Metabolism and Disposition | 2011 | 42 |
| 35 | Organic Cation Transporter-Mediated Ergothioneine Uptake in Mouse Neural Progenitor Cells Suppresses Proliferation and Promotes Differentiation into Neurons | PLoS ONE | 2014 | 42 |
| 36 | High-Speed SICM for the Visualization of Nanoscale Dynamic Structural Changes in Hippocampal Neurons | Analytical Chemistry | 2020 | 42 |
| 37 | Critical evaluation and methodological positioning of the transdermal microdialysis technique. A review | Journal of Controlled Release | 2016 | 41 |
| 38 | Impairment of the carnitine/organic cation transporter 1–ergothioneine axis is mediated by intestinal transporter dysfunction in chronic kidney disease | Kidney International | 2017 | 39 |
| 39 | Role of Organic Cation/Carnitine Transporter 1 in Uptake of Phenformin and Inhibitory Effect on Complex I Respiration in Mitochondria | Toxicological Sciences | 2013 | 37 |
| 40 | Relationship between Physical Parameters of Various Metal Ions and Binding Affinity for Alginate | Biological and Pharmaceutical Bulletin | 2016 | 35 |
| 41 | Studies on conformation and reactivity—I | Tetrahedron | 1965 | 33 |
| 42 | Cloning of the dog bile salt export pump (BSEP; ABCB11) and functional comparison with the human and rat proteins | Biopharmaceutics and Drug Disposition | 2008 | 33 |
| 43 | A Method for isolating Bacteria capable of producing 6-Aminopenicillanic Acid from Benzylpenicillin | Nature | 1961 | 32 |
| 44 | Uptake transporter organic anion transporting polypeptide 1B3 contributes to the growth of estrogen-dependent breast cancer | Journal of Steroid Biochemistry and Molecular Biology | 2010 | 31 |
| 45 | Effect of Milk on the Pharmacokinetics of Oseltamivir in Healthy Volunteers | Journal of Pharmaceutical Sciences | 2011 | 31 |
| 46 | Quantitative Time-Lapse Imaging-Based Analysis of Drug-Drug Interaction Mediated by Hepatobiliary Transporter, Multidrug Resistance-Associated Protein 2, in Sandwich-Cultured Rat Hepatocytes | Drug Metabolism and Disposition | 2011 | 31 |
| 47 | The change of pharmacokinetics of fexofenadine enantiomers through the single and simultaneous grapefruit juice ingestion | Drug Metabolism and Pharmacokinetics | 2015 | 31 |
| 48 | Increased Plasma Concentrations of Unbound SN-38, the Active Metabolite of Irinotecan, in Cancer Patients with Severe Renal Failure | Pharmaceutical Research | 2016 | 31 |
| 49 | Hydrolysis and Metabolism by Soil Bacteria of Benzoyl Derivatives of D- and L-Forms of some Amino-acids | Nature | 1952 | 30 |
| 50 | Localization of Xenobiotic Transporter OCTN1/SLC22A4 in Hepatic Stellate Cells and Its Protective Role in Liver Fibrosis | Journal of Pharmaceutical Sciences | 2016 | 30 |
