# | Title | Journal | Year | Citations |
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1 | Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis | Annals of Neurology | 1996 | 2,365 |
2 | Statin-associated muscle symptoms: impact on statin therapy—European Atherosclerosis Society Consensus Panel Statement on Assessment, Aetiology and Management | European Heart Journal | 2015 | 1,024 |
3 | Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis | Journal of Experimental Medicine | 2009 | 878 |
4 | Etiology of Severe Pneumonia in the Very Elderly | American Journal of Respiratory and Critical Care Medicine | 2001 | 841 |
5 | Gateways to the FANTOM5 promoter level mammalian expression atlas | Genome Biology | 2015 | 687 |
6 | Television Watching, Energy Intake, and Obesity in US Children | JAMA Pediatrics | 2001 | 648 |
7 | Grading quality of evidence and strength of recommendations in clinical practice guidelines | Allergy: European Journal of Allergy and Clinical Immunology | 2009 | 596 |
8 | Pulmonary Function Is a Long-term Predictor of Mortality in the General Population | Chest | 2000 | 512 |
9 | The Relationship Between Motor Proficiency and Physical Activity in Children | Pediatrics | 2006 | 498 |
10 | Effect of obesity on intensive care morbidity and mortality: A meta-analysis* | Critical Care Medicine | 2008 | 467 |
11 | Repeated Stress Causes Cognitive Impairment by Suppressing Glutamate Receptor Expression and Function in Prefrontal Cortex | Neuron | 2012 | 456 |
12 | A Randomized Trial of the Effects of Reducing Television Viewing and Computer Use on Body Mass Index in Young Children | JAMA Pediatrics | 2008 | 448 |
13 | Family-based obesity treatment, then and now: Twenty-five years of pediatric obesity treatment. | Health Psychology | 2007 | 427 |
14 | Targeting cells with single vectors using multiple-feature Boolean logic | Nature Methods | 2014 | 427 |
15 | MT1 and MT2 Melatonin Receptors: A Therapeutic Perspective | Annual Review of Pharmacology and Toxicology | 2016 | 424 |
16 | The Pyruvate Dehydrogenase Complexes: Structure-based Function and Regulation | Journal of Biological Chemistry | 2014 | 418 |
17 | Acute stress enhances glutamatergic transmission in prefrontal cortex and facilitates working memory | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 391 |
18 | Cognition in multiple sclerosis | Neurology | 2018 | 384 |
19 | The Functional Independence Measure for Children (WeeFIM) | Clinical Pediatrics | 1994 | 366 |
20 | Syndrome X and Mortality: A Population-based Study | American Journal of Epidemiology | 1998 | 356 |
21 | Prediction of Neuropsychological Impairment in Multiple Sclerosis | Archives of Neurology | 2004 | 351 |
22 | Magnetic resonance studies of intramuscular interferon ?-1a for relapsing multiple sclerosis | Annals of Neurology | 1998 | 346 |
23 | Morbid Obesity in the Medical ICU | Chest | 2001 | 343 |
24 | Retinoic acid biosynthesis and metabolism | FASEB Journal | 1996 | 337 |
25 | Biopsychosocial Aspects of Functional Gastrointestinal Disorders: How Central and Environmental Processes Contribute to the Development and Expression of Functional Gastrointestinal Disorders | Gastroenterology | 2016 | 327 |
26 | Competing demands of primary care: a model for the delivery of clinical preventive services | Journal of Family Practice | 1994 | 322 |
27 | The molecular basis of cryosurgery | BJU International | 2005 | 314 |
28 | Origin and Uses ofPrimum Non Nocere-Above All, Do No Harm! | Journal of Clinical Pharmacology | 2005 | 311 |
29 | Functional Cooperation between Interleukin-17 and Tumor Necrosis Factor-α Is Mediated by CCAAT/Enhancer-binding Protein Family Members | Journal of Biological Chemistry | 2004 | 309 |
30 | An essential role for IL-17 in preventing pathogen-initiated bone destruction: recruitment of neutrophils to inflamed bone requires IL-17 receptor–dependent signals | Blood | 2007 | 306 |
31 | Long-range and short-range mechanisms of hydrophobic attraction and hydrophilic repulsion in specific and aspecific interactions | Journal of Molecular Recognition | 2003 | 303 |
32 | Premenopausal Breast Cancer Risk and Intake of Vegetables, Fruits, and Related Nutrients | Journal of the National Cancer Institute | 1996 | 295 |
33 | The Relationship Between Bone Mineral Density and Periodontitis in Postmenopausal Women | Journal of Periodontology | 2000 | 295 |
34 | Molecular mechanisms of iron uptake in fungi | Molecular Microbiology | 2003 | 294 |
35 | Review of epidemiology and clinical risk factors for severe respiratory syncytial virus (RSV) infection | Journal of Pediatrics | 2003 | 293 |
36 | Clozapine N-Oxide Administration Produces Behavioral Effects in Long–Evans Rats: Implications for Designing DREADD Experiments | ENeuro | 2016 | 288 |
37 | The Future Is Now | Psychological Science | 2013 | 287 |
38 | A review on the pharmacological effects of vitexin and isovitexin | Fìtoterapìâ | 2016 | 285 |
39 | Efficacy and current limitations of intravascular stents for intracranial internal carotid, vertebral, and basilar artery aneurysms | Journal of Neurosurgery | 1999 | 283 |
40 | A requirement for CARMA1 in TCR-induced NF-κB activation | Nature Immunology | 2002 | 282 |
41 | Psychological Treatments for Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis. | Journal of Consulting and Clinical Psychology | 2004 | 279 |
42 | Microbiology of Severe Aspiration Pneumonia in Institutionalized Elderly | American Journal of Respiratory and Critical Care Medicine | 2003 | 277 |
43 | Mechanisms for acute stress-induced enhancement of glutamatergic transmission and working memory | Molecular Psychiatry | 2011 | 277 |
44 | Regulation of the pyruvate dehydrogenase complex | Biochemical Society Transactions | 2006 | 272 |
45 | Acute Disseminated Encephalomyelitis in Children | Pediatrics | 2002 | 270 |
46 | Inhibition of Oral Mucosal Cell Wound Healing by Bisphosphonates | Journal of Oral and Maxillofacial Surgery | 2008 | 267 |
47 | Efficient Generation of Myelinating Oligodendrocytes from Primary Progressive Multiple Sclerosis Patients by Induced Pluripotent Stem Cells | Stem Cell Reports | 2014 | 266 |
48 | Identification of Common Transcriptional Regulatory Elements in Interleukin-17 Target Genes | Journal of Biological Chemistry | 2006 | 264 |
49 | Phytosterols as anticancer compounds | Molecular Nutrition and Food Research | 2007 | 264 |
50 | Mitosis detection in breast cancer pathology images by combining handcrafted and convolutional neural network features | Journal of Medical Imaging | 2014 | 264 |