| # | Title | Journal | Year | Citations |
|---|
| 1 | Cardiovascular Magnetic Resonance in Myocarditis: A JACC White Paper | Journal of the American College of Cardiology | 2009 | 2,055 |
| 2 | Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System | Circulation Research | 2020 | 1,478 |
| 3 | Validity and reliability of the Edmonton Frail Scale | Age and Ageing | 2006 | 1,039 |
| 4 | A meta-analysis of the association between adherence to drug therapy and mortality | BMJ: British Medical Journal | 2006 | 1,027 |
| 5 | Cells of the adult human heart | Nature | 2020 | 852 |
| 6 | Anemia Is Common in Heart Failure and Is Associated With Poor Outcomes | Circulation | 2003 | 789 |
| 7 | 2015 Heart Rhythm Society Expert Consensus Statement on the Diagnosis and Treatment of Postural Tachycardia Syndrome, Inappropriate Sinus Tachycardia, and Vasovagal Syncope | Heart Rhythm | 2015 | 694 |
| 8 | Role of the ACE2/Angiotensin 1–7 Axis of the Renin–Angiotensin System in Heart Failure | Circulation Research | 2016 | 664 |
| 9 | Oral Sildenafil Is an Effective and Specific Pulmonary Vasodilator in Patients With Pulmonary Arterial Hypertension | Circulation | 2002 | 586 |
| 10 | Ventricular Remodeling After Infarction and the Extracellular Collagen Matrix | Circulation | 2003 | 577 |
| 11 | Multi-ethnic genome-wide association study for atrial fibrillation | Nature Genetics | 2018 | 552 |
| 12 | An Abnormal Mitochondrial–Hypoxia Inducible Factor-1α–Kv Channel Pathway Disrupts Oxygen Sensing and Triggers Pulmonary Arterial Hypertension in Fawn Hooded Rats | Circulation | 2006 | 530 |
| 13 | Why Do Patients With Atrial Fibrillation Not Receive Warfarin? | Archives of Internal Medicine | 2000 | 509 |
| 14 | Efficacy of β blockers in patients with heart failure plus atrial fibrillation: an individual-patient data meta-analysis | Lancet, The | 2014 | 475 |
| 15 | Effect of calcium-based versus non-calcium-based phosphate binders on mortality in patients with chronic kidney disease: an updated systematic review and meta-analysis | Lancet, The | 2013 | 388 |
| 16 | Angiotensin-Converting Enzyme 2 Suppresses Pathological Hypertrophy, Myocardial Fibrosis, and Cardiac Dysfunction | Circulation | 2010 | 383 |
| 17 | The association among renal insufficiency, pharmacotherapy, and outcomes in 6,427 patients with heart failure and coronary artery disease | Journal of the American College of Cardiology | 2004 | 331 |
| 18 | Declining In-Hospital Mortality and Increasing Heart Failure Incidence in Elderly Patients With First Myocardial Infarction | Journal of the American College of Cardiology | 2009 | 309 |
| 19 | Acute Precipitants of Congestive Heart Failure Exacerbations | Archives of Internal Medicine | 2001 | 281 |
| 20 | Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation | Nature Genetics | 2017 | 279 |
| 21 | Pharmacist Care of Patients With Heart Failure<subtitle>A Systematic Review of Randomized Trials</subtitle> | Archives of Internal Medicine | 2008 | 267 |
| 22 | Human Recombinant ACE2 Reduces the Progression of Diabetic Nephropathy | Diabetes | 2010 | 264 |
| 23 | O2 sensing is preserved in mice lacking the gp91 phox subunit of NADPH oxidase | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 258 |
| 24 | A Randomized Trial of the Effect of Community Pharmacist Intervention on Cholesterol Risk ManagementThe Study of Cardiovascular Risk Intervention by Pharmacists (SCRIP) | Archives of Internal Medicine | 2002 | 251 |
| 25 | Angiotensin Converting Enzyme 2 | Circulation | 2020 | 220 |
| 26 | Cardiac regulation by phosphoinositide 3-kinases and PTEN | Cardiovascular Research | 2008 | 218 |
| 27 | Iron-Overload Cardiomyopathy: Pathophysiology, Diagnosis, and Treatment | Journal of Cardiac Failure | 2010 | 218 |
| 28 | The renin-angiotensin system: going beyond the classical paradigms | American Journal of Physiology - Heart and Circulatory Physiology | 2019 | 218 |
| 29 | Short-term, long-term and paracrine effect of human umbilical cord-derived stem cells in lung injury prevention and repair in experimental bronchopulmonary dysplasia | Thorax | 2013 | 217 |
| 30 | Apoptosis and oxidants in the heart | Translational Research | 2003 | 207 |
| 31 | A Randomized Trial of the Effect of Community Pharmacist and Nurse Care on Improving Blood Pressure Management in Patients With Diabetes Mellitus | Archives of Internal Medicine | 2008 | 202 |
| 32 | Prevention of Angiotensin II–Mediated Renal Oxidative Stress, Inflammation, and Fibrosis by Angiotensin-Converting Enzyme 2 | Hypertension | 2011 | 200 |
| 33 | Exercise training after anterior Q wave myocardial infarction: Importance of regional left ventricular function and topography | Journal of the American College of Cardiology | 1988 | 195 |
| 34 | ACE2 Deficiency Worsens Epicardial Adipose Tissue Inflammation and Cardiac Dysfunction in Response to Diet-Induced Obesity | Diabetes | 2016 | 193 |
| 35 | Mortality and Readmission of Patients With Heart Failure, Atrial Fibrillation, or Coronary Artery Disease Undergoing Noncardiac Surgery | Circulation | 2011 | 186 |
| 36 | Eight Weeks of Exercise Training Increases Aerobic Capacity and Muscle Mass and Reduces Fatigue in Patients With Cirrhosis | Clinical Gastroenterology and Hepatology | 2014 | 180 |
| 37 | Prevalence of severe congenital heart disease after folic acid fortification of grain products: time trend analysis in Quebec, Canada | BMJ: British Medical Journal | 2009 | 179 |
| 38 | Canadian Cardiovascular Society Position Statement on the Management of Thoracic Aortic Disease | Canadian Journal of Cardiology | 2014 | 179 |
| 39 | Remodeling of the Myocardium and Potential Targets in the Collagen Degradation and Synthesis Pathways | Current Drug Targets Cardiovascular & Haematological Disorders | 2003 | 175 |
| 40 | Loss of Apelin Exacerbates Myocardial Infarction Adverse Remodeling and Ischemia‐reperfusion Injury: Therapeutic Potential of Synthetic Apelin Analogues | Journal of the American Heart Association | 2013 | 171 |
| 41 | Effect of Vericiguat vs Placebo on Quality of Life in Patients With Heart Failure and Preserved Ejection Fraction | JAMA - Journal of the American Medical Association | 2020 | 170 |
| 42 | Trade-off of myocardial infarction vs. bleeding types on mortality after acute coronary syndrome: lessons from the Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome (TRACER) randomized trial | European Heart Journal | 2017 | 164 |
| 43 | Angiotensin 1–7 Ameliorates Diabetic Cardiomyopathy and Diastolic Dysfunction in db/db Mice by Reducing Lipotoxicity and Inflammation | Circulation: Heart Failure | 2014 | 158 |
| 44 | Epicardial adipose tissue as a metabolic transducer: role in heart failure and coronary artery disease | Heart Failure Reviews | 2017 | 156 |
| 45 | Short- and long-term outcomes following atrial fibrillation in patients with acute coronary syndromes with or without ST-segment elevation | Heart | 2008 | 155 |
| 46 | Diagnosis, Prevention, and Management of Statin Adverse Effects and Intolerance: Canadian Working Group Consensus Update | Canadian Journal of Cardiology | 2013 | 153 |
| 47 | Impact of specialist follow-up in outpatients with congestive heart failure | Cmaj | 2005 | 151 |
| 48 | The Role of K+Channels in Determining Pulmonary Vascular Tone, Oxygen Sensing, Cell Proliferation, and Apoptosis: Implications in Hypoxic Pulmonary Vasoconstriction and Pulmonary Arterial Hypertension | Microcirculation | 2006 | 150 |
| 49 | Comorbidity, healthcare utilisation and process of care measures in patients with congenital heart disease in the UK: cross-sectional, population-based study with case-control analysis | Heart | 2008 | 147 |
| 50 | Aldosterone blockade and left ventricular dysfunction: a systematic review of randomized clinical trials | European Heart Journal | 2008 | 145 |
