| # | Title | Journal | Year | Citations |
|---|
| 1 | Chronic systemic pesticide exposure reproduces features of Parkinson's disease | Nature Neuroscience | 2000 | 3,216 |
| 2 | Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing | Nature Genetics | 2019 | 1,962 |
| 3 | Phenomenology and classification of dystonia: A consensus update | Movement Disorders | 2013 | 1,754 |
| 4 | Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease | Nature Genetics | 2011 | 1,676 |
| 5 | Comparison of Warfarin and Aspirin for Symptomatic Intracranial Arterial Stenosis | New England Journal of Medicine | 2005 | 1,620 |
| 6 | Solitaire flow restoration device versus the Merci Retriever in patients with acute ischaemic stroke (SWIFT): a randomised, parallel-group, non-inferiority trial | Lancet, The | 2012 | 1,213 |
| 7 | Analysis of shared heritability in common disorders of the brain | Science | 2018 | 1,085 |
| 8 | Neuregulins: functions, forms, and signaling strategies | Experimental Cell Research | 2003 | 942 |
| 9 | Exogenous Induction of Cerebral -Amyloidogenesis Is Governed by Agent and Host | Science | 2006 | 875 |
| 10 | Core assessment program for intracerebral transplantations (CAPIT) | Movement Disorders | 1992 | 874 |
| 11 | Discussion | Neuroscience | 1998 | 867 |
| 12 | International multicenter pilot study of the first comprehensive self-completed nonmotor symptoms questionnaire for Parkinson's disease: The NMSQuest study | Movement Disorders | 2006 | 865 |
| 13 | The metric properties of a novel non‐motor symptoms scale for Parkinson's disease: Results from an international pilot study | Movement Disorders | 2007 | 838 |
| 14 | Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways | Science | 2015 | 823 |
| 15 | Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease | Nature Genetics | 2017 | 783 |
| 16 | Striatal dopamine nerve terminal markers in human, chronic methamphetamine users | Nature Medicine | 1996 | 686 |
| 17 | Premotor Cortex Activation during Observation and Naming of Familiar Tools | NeuroImage | 1997 | 678 |
| 18 | A standardized method for measuring intracranial arterial stenosis | American Journal of Neuroradiology | 2000 | 625 |
| 19 | Distinct Role of Long 3′ UTR BDNF mRNA in Spine Morphology and Synaptic Plasticity in Hippocampal Neurons | Cell | 2008 | 604 |
| 20 | Subcutaneous Rotenone Exposure Causes Highly Selective Dopaminergic Degeneration and α-Synuclein Aggregation | Experimental Neurology | 2003 | 599 |
| 21 | Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19 | Nature Immunology | 2020 | 563 |
| 22 | Pathogenic protein seeding in alzheimer disease and other neurodegenerative disorders | Annals of Neurology | 2011 | 536 |
| 23 | ProTECT: A Randomized Clinical Trial of Progesterone for Acute Traumatic Brain Injury | Annals of Emergency Medicine | 2007 | 522 |
| 24 | Peripherally Applied Aβ-Containing Inoculates Induce Cerebral β-Amyloidosis | Science | 2010 | 519 |
| 25 | Mitochondrial biogenesis in the anticonvulsant mechanism of the ketogenic diet | Annals of Neurology | 2006 | 517 |
| 26 | Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization | Nature Medicine | 1999 | 516 |
| 27 | The thalamostriatal system: a highly specific network of the basal ganglia circuitry | Trends in Neurosciences | 2004 | 514 |
| 28 | Animal models of Parkinson's disease | BioEssays | 2002 | 494 |
| 29 | Diagnostic criteria for psychosis in Parkinson's disease: Report of an NINDS, NIMH work group | Movement Disorders | 2007 | 474 |
| 30 | Prevalence of nonmotor symptoms in Parkinson's disease in an international setting; Study using nonmotor symptoms questionnaire in 545 patients | Movement Disorders | 2007 | 461 |
| 31 | The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans | Science | 2019 | 460 |
| 32 | Toward a Neuroimaging Treatment Selection Biomarker for Major Depressive Disorder | JAMA Psychiatry | 2013 | 455 |
| 33 | Glutamate-Dependent Neuroglial Calcium Signaling Differs Between Young and Adult Brain | Science | 2013 | 445 |
| 34 | Pathophysiology of Parkinsonism | Clinical Neurophysiology | 2008 | 433 |
| 35 | The primate subthalamic nucleus. III. Changes in motor behavior and neuronal activity in the internal pallidum induced by subthalamic inactivation in the MPTP model of parkinsonism | Journal of Neurophysiology | 1994 | 388 |
| 36 | Defining Critical White Matter Pathways Mediating Successful Subcallosal Cingulate Deep Brain Stimulation for Treatment-Resistant Depression | Biological Psychiatry | 2014 | 375 |
| 37 | Ectopically Expressed CAG Repeats Cause Intranuclear Inclusions and a Progressive Late Onset Neurological Phenotype in the Mouse | Cell | 1997 | 350 |
| 38 | The primate subthalamic nucleus. I. Functional properties in intact animals | Journal of Neurophysiology | 1994 | 346 |
| 39 | Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis | Nature Genetics | 2009 | 344 |
| 40 | KINECT 3: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Trial of Valbenazine for Tardive Dyskinesia | American Journal of Psychiatry | 2017 | 339 |
| 41 | Version 3 of the Alzheimer Disease Centers’ Neuropsychological Test Battery in the Uniform Data Set (UDS) | Alzheimer Disease and Associated Disorders | 2018 | 337 |
| 42 | Deep Brain Stimulation for Neurologic and Neuropsychiatric Disorders | Neuron | 2006 | 311 |
| 43 | Exome-wide Rare Variant Analysis Identifies TUBA4A Mutations Associated with Familial ALS | Neuron | 2014 | 308 |
| 44 | Adaptive deep brain stimulation for Parkinson’s disease using motor cortex sensing | Journal of Neural Engineering | 2018 | 299 |
| 45 | Functional Interaction between Monoamine Plasma Membrane Transporters and the Synaptic PDZ Domain–Containing Protein PICK1 | Neuron | 2001 | 294 |
| 46 | Progesterone protects against lipid peroxidation following traumatic brain injury in rats | Molecular and Chemical Neuropathology | 1997 | 292 |
| 47 | Propagation and spread of pathogenic protein assemblies in neurodegenerative diseases | Nature Neuroscience | 2018 | 289 |
| 48 | Functional fetal nigral grafts in a patient with Parkinson's disease: Chemoanatomic, ultrastructural, and metabolic studies | | 1996 | 286 |
| 49 | Loss of Apolipoprotein E Receptor LR11 in Alzheimer Disease | Archives of Neurology | 2004 | 286 |
| 50 | Neurodegenerative Diseases: Expanding the Prion Concept | Annual Review of Neuroscience | 2015 | 278 |
