| # | Title | Journal | Year | Citations |
|---|
| 1 | NAD(P)H Oxidase | Circulation Research | 2000 | 2,690 |
| 2 | Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. | Circulation Research | 1994 | 2,512 |
| 3 | The Global Health and Economic Burden of Hospitalizations for Heart Failure | Journal of the American College of Cardiology | 2014 | 1,640 |
| 4 | Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system | American Journal of Physiology - Cell Physiology | 2007 | 1,589 |
| 5 | Reactive Oxygen Species in Metabolic and Inflammatory Signaling | Circulation Research | 2018 | 1,212 |
| 6 | Modulation of Protein Kinase Activity and Gene Expression by Reactive Oxygen Species and Their Role in Vascular Physiology and Pathophysiology | Arteriosclerosis, Thrombosis, and Vascular Biology | 2000 | 859 |
| 7 | Oxidative Stress and Cardiovascular Injury | Circulation | 2003 | 800 |
| 8 | Novel gp91 phox Homologues in Vascular Smooth Muscle Cells | Circulation Research | 2001 | 787 |
| 9 | Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets | Nature Reviews Drug Discovery | 2011 | 763 |
| 10 | Nox proteins in signal transduction | Free Radical Biology and Medicine | 2009 | 744 |
| 11 | Insights From the NHLBI-Sponsored Women’s Ischemia Syndrome Evaluation (WISE) Study | Journal of the American College of Cardiology | 2006 | 727 |
| 12 | Direct stimulation of Jak/STAT pathway by the angiotensin II AT1 receptor | Nature | 1995 | 710 |
| 13 | p22 Is a Critical Component of the Superoxide-generating NADH/NADPH Oxidase System and Regulates Angiotensin IIinduced Hypertrophy in Vascular Smooth Muscle Cells | Journal of Biological Chemistry | 1996 | 708 |
| 14 | Oxidative Stress and Cardiovascular Injury | Circulation | 2003 | 695 |
| 15 | NAD(P)H Oxidase 4 Mediates Transforming Growth Factor-β1–Induced Differentiation of Cardiac Fibroblasts Into Myofibroblasts | Circulation Research | 2005 | 692 |
| 16 | Angiotensin II Stimulation of NAD(P)H Oxidase Activity | Circulation Research | 2002 | 672 |
| 17 | Biochemistry, Physiology, and Pathophysiology of NADPH Oxidases in the Cardiovascular System | Circulation Research | 2012 | 669 |
| 18 | Interleukin 17 Promotes Angiotensin II–Induced Hypertension and Vascular Dysfunction | Hypertension | 2010 | 662 |
| 19 | Insights From the NHLBI-Sponsored Women’s Ischemia Syndrome Evaluation (WISE) Study | Journal of the American College of Cardiology | 2006 | 620 |
| 20 | Role of NADH/NADPH Oxidase–Derived H2O2in Angiotensin II–Induced Vascular Hypertrophy | Hypertension | 1998 | 592 |
| 21 | p38 Mitogen-activated Protein Kinase Is a Critical Component of the Redox-sensitive Signaling Pathways Activated by Angiotensin II | Journal of Biological Chemistry | 1998 | 588 |
| 22 | Oscillatory and Steady Laminar Shear Stress Differentially Affect Human Endothelial Redox State | Circulation Research | 1998 | 567 |
| 23 | Engineering of human brain organoids with a functional vascular-like system | Nature Methods | 2019 | 551 |
| 24 | Reactive Oxygen Species Mediate the Activation of Akt/Protein Kinase B by Angiotensin II in Vascular Smooth Muscle Cells | Journal of Biological Chemistry | 1999 | 504 |
| 25 | The ADVANCE study: a randomized study to evaluate the effects of cinacalcet plus low-dose vitamin D on vascular calcification in patients on hemodialysis | Nephrology Dialysis Transplantation | 2011 | 491 |
| 26 | Direct Interaction of the Novel Nox Proteins with p22phox Is Required for the Formation of a Functionally Active NADPH Oxidase | Journal of Biological Chemistry | 2004 | 468 |
| 27 | Measurement of Reactive Oxygen Species in Cardiovascular Studies | Hypertension | 2007 | 457 |
| 28 | Regulation of Signal Transduction by Reactive Oxygen Species in the Cardiovascular System | Circulation Research | 2015 | 397 |
| 29 | Nox1 Overexpression Potentiates Angiotensin II-Induced Hypertension and Vascular Smooth Muscle Hypertrophy in Transgenic Mice | Circulation | 2005 | 396 |
| 30 | Partial carotid ligation is a model of acutely induced disturbed flow, leading to rapid endothelial dysfunction and atherosclerosis | American Journal of Physiology - Heart and Circulatory Physiology | 2009 | 396 |
| 31 | Oxidative stress and diabetic cardiovascular complications | Free Radical Biology and Medicine | 2006 | 392 |
| 32 | Poldip2, a Novel Regulator of Nox4 and Cytoskeletal Integrity in Vascular Smooth Muscle Cells | Circulation Research | 2009 | 386 |
| 33 | Transcriptional and Posttranscriptional Regulation of Endothelial Nitric Oxide Synthase Expression by Hydrogen Peroxide | Circulation Research | 2000 | 383 |
| 34 | Absence of Coronary Artery Calcification and All-Cause Mortality | JACC: Cardiovascular Imaging | 2009 | 382 |
| 35 | Angiotensin II Induces Monocyte Chemoattractant Protein-1 Gene Expression in Rat Vascular Smooth Muscle Cells | Circulation Research | 1998 | 374 |
| 36 | Reactive oxygen species as mediators of angiotensin II signaling | Regulatory Peptides | 2000 | 372 |
| 37 | MiR-21 is induced in endothelial cells by shear stress and modulates apoptosis and eNOS activity | Biochemical and Biophysical Research Communications | 2010 | 348 |
| 38 | Sex Differences in Hospital Mortality After Coronary Artery Bypass Surgery | Circulation | 2002 | 345 |
| 39 | National Trends in Use of Computed Tomography in the Emergency Department | Annals of Emergency Medicine | 2011 | 342 |
| 40 | The economic consequences of available diagnostic and prognostic strategies for the evaluation of stable angina patients: an observational assessment of the value of precatheterization ischemia | Journal of the American College of Cardiology | 1999 | 336 |
| 41 | Randomized trial of a daily electronic home monitoring system in patients with advanced heart failure: the Weight Monitoring in Heart Failure (WHARF) trial | American Heart Journal | 2003 | 329 |
| 42 | Flow-dependent regulation of endothelial nitric oxide synthase: role of protein kinases | American Journal of Physiology - Cell Physiology | 2003 | 326 |
| 43 | NADPH oxidases and angiotensin II receptor signaling | Molecular and Cellular Endocrinology | 2009 | 321 |
| 44 | Reactive oxygen species signaling in vascular smooth muscle cells | Cardiovascular Research | 2006 | 298 |
| 45 | Nox4 Is Required for Maintenance of the Differentiated Vascular Smooth Muscle Cell Phenotype | Arteriosclerosis, Thrombosis, and Vascular Biology | 2007 | 296 |
| 46 | Chronic Mechanical Circulatory Support for Inotrope-Dependent Heart Failure Patients Who Are Not Transplant Candidates | Journal of the American College of Cardiology | 2007 | 295 |
| 47 | Extracellular superoxide dismutase and cardiovascular disease | Cardiovascular Research | 2002 | 287 |
| 48 | Basic Mechanisms of Oxidative Stress and Reactive Oxygen Species in Cardiovascular Injury | Trends in Cardiovascular Medicine | 2007 | 282 |
| 49 | Shear Stress Regulates Endothelial Nitric Oxide Synthase Expression Through c-Src by Divergent Signaling Pathways | Circulation Research | 2001 | 274 |
| 50 | Epicardial adipose tissue and coronary artery plaque characteristics | Atherosclerosis | 2010 | 273 |
