| # | Title | Journal | Year | Citations |
|---|
| 1 | Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method | Methods | 2001 | 145,087 |
| 2 | Pharmaceutical Applications of Solid Dispersion Systems | Journal of Pharmaceutical Sciences | 1971 | 1,452 |
| 3 | Quantitative Reverse Transcription–Polymerase Chain Reaction to Study mRNA Decay: Comparison of Endpoint and Real-Time Methods | Analytical Biochemistry | 2000 | 918 |
| 4 | Diabetic Kidney Disease: A Report From an ADA Consensus Conference | Diabetes Care | 2014 | 781 |
| 5 | Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes | Nature Genetics | 2017 | 472 |
| 6 | Diabetic Kidney Disease: A Report From an ADA Consensus Conference | American Journal of Kidney Diseases | 2014 | 439 |
| 7 | Influence of porosity on mechanical properties and in vivo response of Ti6Al4V implants | Acta Biomaterialia | 2010 | 361 |
| 8 | Computational Thermostabilization of an Enzyme | Science | 2005 | 337 |
| 9 | Microwave-sintered 3D printed tricalcium phosphate scaffolds for bone tissue engineering | Journal of Tissue Engineering and Regenerative Medicine | 2013 | 300 |
| 10 | Shift Work: Disrupted Circadian Rhythms and Sleep—Implications for Health and Well-being | Current Sleep Medicine Reports | 2017 | 279 |
| 11 | Clinical toxicities of nanocarrier systems | Advanced Drug Delivery Reviews | 2008 | 277 |
| 12 | Liver tumor induction in B6C3F1 mice by dichloroacetate and trichloroacetate | Toxicology | 1990 | 269 |
| 13 | Pharmacometrics of Stilbenes: Seguing Towards the Clinic | Current Clinical Pharmacology | 2006 | 258 |
| 14 | Pharmacometrics of pterostilbene: preclinical pharmacokinetics and metabolism, anticancer, antiinflammatory, antioxidant and analgesic activity | Phytotherapy Research | 2008 | 256 |
| 15 | Neutrophil‐Based Drug Delivery Systems | Advanced Materials | 2018 | 236 |
| 16 | Blood Cultures Positive for Coagulase-Negative Staphylococci: Antisepsis, Pseudobacteremia, and Therapy of Patients | Journal of Clinical Microbiology | 1998 | 230 |
| 17 | Metabolism of Flavonoids via Enteric Recycling: Role of Intestinal Disposition | Journal of Pharmacology and Experimental Therapeutics | 2003 | 226 |
| 18 | Absorption and Metabolism of Flavonoids in the Caco-2 Cell Culture Model and a Perused Rat Intestinal Model | Drug Metabolism and Disposition | 2002 | 224 |
| 19 | Neutrophil-Mediated Delivery of Therapeutic Nanoparticles across Blood Vessel Barrier for Treatment of Inflammation and Infection | ACS Nano | 2015 | 207 |
| 20 | National Trends in the Prevalence of Attention-Deficit/Hyperactivity Disorder and the Prescribing of Methylphenidate among School-Age Children: 1990-1995 | Clinical Pediatrics | 1999 | 200 |
| 21 | Flip-flop pharmacokinetics – delivering a reversal of disposition: challenges and opportunities during drug development | Therapeutic Delivery | 2011 | 194 |
| 22 | Tick-Borne Relapsing Fever | Infectious Disease Clinics of North America | 2008 | 189 |
| 23 | Enhanced intestinal absorption of cyclosporine in rats through the reduction of emulsion droplet size | Pharmaceutical Research | 1989 | 176 |
| 24 | Advances in Understanding the Actions of Nitrous Oxide | Anesthesia Progress | 2007 | 172 |
| 25 | Metformin hydrochloride in the treatment of type 2 diabetes mellitus: A clinical review with a focus on dual therapy | Clinical Therapeutics | 2003 | 160 |
| 26 | A novel method for assessing dissolution of aerosol inhaler products | International Journal of Pharmaceutics | 2003 | 157 |
| 27 | Understanding the influence of MgO and SrO binary doping on the mechanical and biological properties of β-TCP ceramics | Acta Biomaterialia | 2010 | 152 |
| 28 | 3D printed tricalcium phosphate bone tissue engineering scaffolds: effect of SrO and MgO doping on in vivo osteogenesis in a rat distal femoral defect model | Biomaterials Science | 2013 | 149 |
| 29 | High yield, scalable and remotely drug-loaded neutrophil-derived extracellular vesicles (EVs) for anti-inflammation therapy | Biomaterials | 2017 | 147 |
| 30 | Sex differences in antinociceptive and motoric effects of cannabinoids | European Journal of Pharmacology | 2001 | 144 |
| 31 | Metabolism and lipoperoxidative activity of trichloroacetate and dichloroacetate in rats and mice | Toxicology and Applied Pharmacology | 1992 | 141 |
| 32 | Sodium-Glucose Co-Transport Inhibitors | Drugs | 2010 | 140 |
| 33 | Understanding in vivo response and mechanical property variation in MgO, SrO and SiO2 doped β-TCP | Bone | 2011 | 136 |
| 34 | The structure of Escherichia coli cytosine deaminase 1 1Edited by I. A. Wilson | Journal of Molecular Biology | 2002 | 135 |
| 35 | Rewiring of Glutamine Metabolism Is a Bioenergetic Adaptation of Human Cells with Mitochondrial DNA Mutations | Cell Metabolism | 2018 | 135 |
| 36 | Photosensitization Priming of Tumor Microenvironments Improves Delivery of Nanotherapeutics via Neutrophil Infiltration | Advanced Materials | 2017 | 134 |
| 37 | Metabolism of Flavonoids via Enteric Recycling: Mechanistic Studies of Disposition of Apigenin in the Caco-2 Cell Culture Model | Journal of Pharmacology and Experimental Therapeutics | 2003 | 132 |
| 38 | Unfilled Prescriptions of Medicare Beneficiaries: Prevalence, Reasons, and Types of Medicines Prescribed | Journal of Managed Care Pharmacy | 2008 | 131 |
| 39 | Cell membrane-formed nanovesicles for disease-targeted delivery | Journal of Controlled Release | 2016 | 126 |
| 40 | Differential chemistry (structure), mechanism of action, and pharmacology of GLP-1 receptor agonists and DPP-4 inhibitors | Journal of the American Pharmacists Association: JAPhA | 2009 | 115 |
| 41 | Multiple Peaking Phenomena in Pharmacokinetic Disposition | Clinical Pharmacokinetics | 2010 | 115 |
| 42 | Estrogen Carcinogenesis in Hamster Tissues: A Critical Review* | Endocrine Reviews | 1990 | 114 |
| 43 | Methods of analysis and separation of chiral flavonoids | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2007 | 114 |
| 44 | Is Attention Deficit Hyperactivity Disorder Increasing Among Girls in the US? | CNS Drugs | 2002 | 113 |
| 45 | Absorption and metabolism of genistein and its five isoflavone analogs in the human intestinal Caco-2 model | Cancer Chemotherapy and Pharmacology | 2005 | 113 |
| 46 | Nanoparticle Targeting of Neutrophils for Improved Cancer Immunotherapy | Advanced Healthcare Materials | 2016 | 113 |
| 47 | Influence of Ethanol Consumption on Natural Killer Cell Activity in Mice | Alcoholism: Clinical and Experimental Research | 1989 | 112 |
| 48 | Stability studies on the cyanobacterial nicotinic alkaloid snatoxin-A | Toxicon | 1991 | 111 |
| 49 | Leukocyte-mediated Delivery of Nanotherapeutics in Inflammatory and Tumor Sites | Theranostics | 2017 | 111 |
| 50 | Type 2 diabetes: Where we are today: An overview of disease burden, current treatments, and treatment strategies | Journal of the American Pharmacists Association: JAPhA | 2009 | 110 |
