# | Title | Journal | Year | Citations |
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1 | Biological, clinical and population relevance of 95 loci for blood lipids | Nature | 2010 | 3,300 |
2 | Mixed linear model approach adapted for genome-wide association studies | Nature Genetics | 2010 | 2,090 |
3 | Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans | Nature Genetics | 2008 | 1,295 |
4 | Common variants at 30 loci contribute to polygenic dyslipidemia | Nature Genetics | 2009 | 1,249 |
5 | Common variants associated with plasma triglycerides and risk for coronary artery disease | Nature Genetics | 2013 | 768 |
6 | Modulation of gut microbiota during probiotic-mediated attenuation of metabolic syndrome in high fat diet-fed mice | ISME Journal | 2015 | 720 |
7 | Timing of food intake predicts weight loss effectiveness | International Journal of Obesity | 2013 | 492 |
8 | Exome-wide association study of plasma lipids in >300,000 individuals | Nature Genetics | 2017 | 486 |
9 | Genome-Wide Association Study of Plasma Polyunsaturated Fatty Acids in the InCHIANTI Study | PLoS Genetics | 2009 | 358 |
10 | Epigenetics and cardiovascular disease | Nature Reviews Cardiology | 2010 | 348 |
11 | The rubber tree genome reveals new insights into rubber production and species adaptation | Nature Plants | 2016 | 340 |
12 | Saturated Fats and Health: A Reassessment and Proposal for Food-Based Recommendations | Journal of the American College of Cardiology | 2020 | 337 |
13 | Lipoprotein(a) Levels in Familial Hypercholesterolemia | Journal of the American College of Cardiology | 2014 | 299 |
14 | A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study | BMC Medical Genetics | 2007 | 291 |
15 | Association of Low-Frequency and Rare Coding-Sequence Variants with Blood Lipids and Coronary Heart Disease in 56,000 Whites and Blacks | American Journal of Human Genetics | 2014 | 289 |
16 | Calcific Aortic Valve Disease | Arteriosclerosis, Thrombosis, and Vascular Biology | 2014 | 277 |
17 | Long-term secondary prevention of cardiovascular disease with a Mediterranean diet and a low-fat diet (CORDIOPREV): a randomised controlled trial | Lancet, The | 2022 | 239 |
18 | Serum Selenium Concentrations and Diabetes in U.S. Adults: National Health and Nutrition Examination Survey (NHANES) 2003–2004 | Environmental Health Perspectives | 2009 | 232 |
19 | NUTRITIONAL GENOMICS | Annual Review of Genomics and Human Genetics | 2004 | 217 |
20 | Meta‐research: The art of getting it wrong | Research Synthesis Methods | 2010 | 198 |
21 | Dietary Fat Intake Determines the Effect of a Common Polymorphism in the Hepatic Lipase Gene Promoter on High-Density Lipoprotein Metabolism | Circulation | 2002 | 187 |
22 | Polyunsaturated fatty acids modulate the effects of the APOA1 G-A polymorphism on HDL-cholesterol concentrations in a sex-specific manner: the Framingham Study | American Journal of Clinical Nutrition | 2002 | 173 |
23 | Environmental chemicals and DNA methylation in adults: a systematic review of the epidemiologic evidence | Clinical Epigenetics | 2015 | 173 |
24 | Bitter, Sweet, Salty, Sour and Umami Taste Perception Decreases with Age: Sex-Specific Analysis, Modulation by Genetic Variants and Taste-Preference Associations in 18 to 80 Year-Old Subjects | Nutrients | 2018 | 165 |
25 | Serum selenium and serum lipids in US adults: National Health and Nutrition Examination Survey (NHANES) 2003–2004 | Atherosclerosis | 2010 | 159 |
26 | Influence of the APOA5 locus on plasma triglyceride, lipoprotein subclasses, and CVD risk in the Framingham Heart Study | Journal of Lipid Research | 2004 | 156 |
27 | APOA2, Dietary Fat, and Body Mass Index | Archives of Internal Medicine | 2009 | 154 |
28 | Metabolic syndrome pathophysiology: The role of adipose tissue | Nutrition, Metabolism and Cardiovascular Diseases | 2007 | 150 |
29 | FTO genetic variants, dietary intake and body mass index: insights from 177 330 individuals | Human Molecular Genetics | 2014 | 148 |
30 | Association Between Physical Activity, Physical Performance, and Inflammatory Biomarkers in an Elderly Population: The InCHIANTI Study | Journals of Gerontology - Series A Biological Sciences and Medical Sciences | 2005 | 143 |
31 | The case for strategic international alliances to harness nutritional genomics for public and personal health | British Journal of Nutrition | 2005 | 137 |
32 | CORonary Diet Intervention with Olive oil and cardiovascular PREVention study (the CORDIOPREV study): Rationale, methods, and baseline characteristics | American Heart Journal | 2016 | 136 |
33 | The APOA5 locus is a strong determinant of plasma triglyceride concentrations across ethnic groups in Singapore | Journal of Lipid Research | 2003 | 135 |
34 | SINGLE NUCLEOTIDE POLYMORPHISMS THAT INFLUENCE LIPID METABOLISM: Interaction with Dietary Factors | Annual Review of Nutrition | 2005 | 135 |
35 | Associations of the FTO rs9939609 and the MC4R rs17782313 polymorphisms with type 2 diabetes are modulated by diet, being higher when adherence to the Mediterranean diet pattern is low | Cardiovascular Diabetology | 2012 | 131 |
36 | Contribution of macronutrients to obesity: implications for precision nutrition | Nature Reviews Endocrinology | 2020 | 128 |
37 | Mediterranean Diet Reduces the Adverse Effect of the TCF7L2-rs7903146 Polymorphism on Cardiovascular Risk Factors and Stroke Incidence | Diabetes Care | 2013 | 126 |
38 | Polyunsaturated Fatty Acids Interact with the PPARA-L162V Polymorphism to Affect Plasma Triglyceride and Apolipoprotein C-III Concentrations in the Framingham Heart Study | Journal of Nutrition | 2005 | 125 |
39 | Diminished skeletal muscle microRNA expression with aging is associated with attenuated muscle plasticity and inhibition of IGF‐1 signaling | FASEB Journal | 2014 | 125 |
40 | Dietary Fiber and the Human Gut Microbiota: Application of Evidence Mapping Methodology | Nutrients | 2017 | 123 |
41 | Clinical characteristics and evaluation of LDL-cholesterol treatment of the Spanish Familial Hypercholesterolemia Longitudinal Cohort Study (SAFEHEART) | Lipids in Health and Disease | 2011 | 122 |
42 | The APOA1/C3/A4/A5 gene cluster, lipid metabolism and cardiovascular disease risk | Current Opinion in Lipidology | 2005 | 116 |
43 | A High Intake of Saturated Fatty Acids Strengthens the Association between the Fat Mass and Obesity-Associated Gene and BMI | Journal of Nutrition | 2011 | 114 |
44 | The −256T>C Polymorphism in the Apolipoprotein A-II Gene Promoter Is Associated with Body Mass Index and Food Intake in the Genetics of Lipid Lowering Drugs and Diet Network Study | Clinical Chemistry | 2007 | 113 |
45 | Fenofibrate Effect on Triglyceride and Postprandial Response of Apolipoprotein A5 Variants | Arteriosclerosis, Thrombosis, and Vascular Biology | 2007 | 113 |
46 | Differential effects of the C1431T and Pro12Ala PPARγ gene variants on plasma lipids and diabetes risk in an Asian population | Journal of Lipid Research | 2004 | 110 |
47 | Curcumin-supplemented diets increase superoxide dismutase activity and mean lifespan in Drosophila | Age | 2013 | 110 |
48 | Dietary Intake of n-6 Fatty Acids Modulates Effect of Apolipoprotein A5 Gene on Plasma Fasting Triglycerides, Remnant Lipoprotein Concentrations, and Lipoprotein Particle Size | Circulation | 2006 | 109 |
49 | Genetic Variation at the Scavenger Receptor Class B Type I Gene Locus Determines Plasma Lipoprotein Concentrations and Particle Size and Interacts with Type 2 Diabetes: The Framingham Study | Journal of Clinical Endocrinology and Metabolism | 2003 | 108 |
50 | CLOCK gene variation is associated with incidence of type-2 diabetes and cardiovascular diseases in type-2 diabetic subjects: dietary modulation in the PREDIMED randomized trial | Cardiovascular Diabetology | 2016 | 108 |