| # | Title | Journal | Year | Citations |
|---|
|
| 1 | Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 41,381 |
| 2 | Nebulized and intravenous colistin in experimental pneumonia caused by Pseudomonas aeruginosa | Intensive Care Medicine | 2010 | 676 |
| 3 | Ultrasound assessment of lung aeration loss during a successful weaning trial predicts postextubation distress* | Critical Care Medicine | 2012 | 395 |
| 4 | Procalcitonin-Guided Use of Antibiotics for Lower Respiratory Tract Infection | New England Journal of Medicine | 2018 | 319 |
| 5 | Perioperative Use of Gabapentinoids for the Management of Postoperative Acute Pain | Anesthesiology | 2020 | 296 |
| 6 | Nebulized Ceftazidime and Amikacin in Ventilator-associated Pneumonia Caused by Pseudomonas aeruginosa | American Journal of Respiratory and Critical Care Medicine | 2011 | 188 |
| 7 | Efficacy of High-dose Nebulized Colistin in Ventilator-associated Pneumonia Caused by Multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii | Anesthesiology | 2012 | 181 |
| 8 | Mechanical Ventilation–associated Lung Fibrosis in Acute Respiratory Distress Syndrome | Anesthesiology | 2014 | 151 |
| 9 | Prehospitalization Antiplatelet Therapy Is Associated With a Reduced Incidence of Acute Lung Injury | Chest | 2011 | 133 |
| 10 | Determinants of long-term outcome in ICU survivors: results from the FROG-ICU study | Critical Care | 2018 | 132 |
| 11 | Being Overweight Is Associated With Greater Survival in ICU Patients | Critical Care Medicine | 2015 | 119 |
| 12 | Multiplane ultrasound approach to quantify pleural effusion at the bedside | Intensive Care Medicine | 2010 | 116 |
| 13 | Delayed Rapid Response Team Activation Is Associated With Increased Hospital Mortality, Morbidity, and Length of Stay in a Tertiary Care Institution* | Critical Care Medicine | 2016 | 113 |
| 14 | Procalcitonin | Critical Care Clinics | 2020 | 111 |
| 15 | Fresh Red Blood Cell Transfusion and Short-Term Pulmonary, Immunologic, and Coagulation Status | American Journal of Respiratory and Critical Care Medicine | 2012 | 107 |
| 16 | Early fluid loading in acute respiratory distress syndrome with septic shock deteriorates lung aeration without impairing arterial oxygenation: a lung ultrasound observational study | Critical Care | 2014 | 101 |
| 17 | Longitudinal Changes in ICU Admissions Among Elderly Patients in the United States* | Critical Care Medicine | 2016 | 91 |
| 18 | Aerosolized Antibiotics for Ventilator-associated Pneumonia | Anesthesiology | 2012 | 88 |
| 19 | Elevated Plasma Levels of sRAGE Are Associated With Nonfocal CT-Based Lung Imaging in Patients With ARDS | Chest | 2016 | 87 |
| 20 | Surfactant Protein D Inhibition of Human Macrophage Uptake ofMycobacterium tuberculosisIs Independent of Bacterial Agglutination | Journal of Immunology | 2002 | 86 |
| 21 | The implementation of clinician designed, human-centered electronic medical record viewer in the intensive care unit: A pilot step-wedge cluster randomized trial | International Journal of Medical Informatics | 2015 | 86 |
| 22 | Limiting ventilator-induced lung injury through individual electronic medical record surveillance* | Critical Care Medicine | 2011 | 82 |
| 23 | Role of Admission Troponin‐T and Serial Troponin‐T Testing in Predicting Outcomes in Severe Sepsis and Septic Shock | Journal of the American Heart Association | 2017 | 79 |
| 24 | Activation of the ATF6 branch of the unfolded protein response in neurons improves stroke outcome | Journal of Cerebral Blood Flow and Metabolism | 2017 | 78 |
| 25 | Statin administration did not influence the progression of lung injury or associated organ failures in a cohort of patients with acute lung injury | Intensive Care Medicine | 2009 | 74 |
| 26 | Potentially Modifiable Risk Factors for Long-Term Cognitive Impairment After Critical Illness: A Systematic Review | Mayo Clinic Proceedings | 2018 | 73 |
| 27 | Five percent albumin for adult burn shock resuscitation: lack of effect on daily multiple organ dysfunction score | Transfusion | 2006 | 71 |
| 28 | New-Onset Heart Failure and Mortality in Hospital Survivors of Sepsis-Related Left Ventricular Dysfunction | Shock | 2018 | 68 |
| 29 | Sepsis during pregnancy | Critical Care Medicine | 2005 | 67 |
| 30 | Extracorporeal liver support in patients with liver failure: a systematic review and meta-analysis of randomized trials | Intensive Care Medicine | 2020 | 67 |
| 31 | Impact of angiotensin-converting enzyme inhibitors or receptor blockers on post-ICU discharge outcome in patients with acute kidney injury | Intensive Care Medicine | 2018 | 66 |
| 32 | Development and validation of electronic surveillance tool for acute kidney injury: A retrospective analysis | Journal of Critical Care | 2015 | 64 |
| 33 | No increase in the incidence of acute kidney injury in a population-based annual temporal trends epidemiology study | Kidney International | 2017 | 62 |
| 34 | Lung Ultrasound in Emergency and Critically Ill Patients | Anesthesiology | 2020 | 62 |
| 35 | Identifying Variations in Blood Use Based on Hemoglobin Transfusion Trigger and Target among Hepatopancreaticobiliary Surgeons | Journal of the American College of Surgeons | 2014 | 60 |
| 36 | Impact of the Electronic Medical Record on Mortality, Length of Stay, and Cost in the Hospital and ICU | Critical Care Medicine | 2015 | 59 |
| 37 | Pseudomonas aeruginosa serotypes in nosocomial pneumonia: prevalence and clinical outcomes | Critical Care | 2014 | 56 |
| 38 | First experience of liver transplantation with type 2 donation after cardiac death in France | Liver Transplantation | 2015 | 55 |
| 39 | XBP1 (X-Box–Binding Protein-1)–Dependent O-GlcNAcylation Is Neuroprotective in Ischemic Stroke in Young Mice and Its Impairment in Aged Mice Is Rescued by Thiamet-G | Stroke | 2017 | 55 |
| 40 | Efficacy of Antitoxin Therapy in Treating Patients With Foodborne Botulism: A Systematic Review and Meta-analysis of Cases, 1923–2016 | Clinical Infectious Diseases | 2018 | 55 |
| 41 | Features of Adult Hyperammonemia Not Due to Liver Failure in the ICU | Critical Care Medicine | 2018 | 55 |
| 42 | Drug-Associated Acute Lung Injury | Chest | 2012 | 52 |
| 43 | Outcomes of Severe Sepsis and Septic Shock Patients on Chronic Antiplatelet Treatment: A Historical Cohort Study | Critical Care Research and Practice | 2013 | 51 |
| 44 | The Effect of an Electronic Checklist on Critical Care Provider Workload, Errors, and Performance | Journal of Intensive Care Medicine | 2016 | 51 |
| 45 | Assessment of the Safety of Discharging Select Patients Directly Home From the Intensive Care Unit | JAMA Internal Medicine | 2018 | 51 |
| 46 | Timing of the Onset of Acute Respiratory Distress Syndrome: A Population-Based Study | Respiratory Care | 2011 | 49 |
| 47 | Short-term and Long-term Impact of the Central Line Workshop on Resident Clinical Performance During Simulated Central Line Placement | Simulation in Healthcare | 2014 | 48 |
| 48 | Mild Stretch-Induced Injury Increases Susceptibility to Interleukin-1β-Induced Release of Matrix Metalloproteinase-9 from Astrocytes | Journal of Neurotrauma | 2011 | 47 |
| 49 | Developing the Surveillance Algorithm for Detection of Failure to Recognize and Treat Severe Sepsis | Mayo Clinic Proceedings | 2015 | 47 |
| 50 | Derivation and validation of the automated search algorithms to identify cognitive impairment and dementia in electronic health records | Journal of Critical Care | 2017 | 47 |
