| # | Title | Journal | Year | Citations |
|---|
|
| 1 | Finding the missing heritability of complex diseases | Nature | 2009 | 7,627 |
| 2 | A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies | PLoS Genetics | 2009 | 3,612 |
| 3 | Biological, clinical and population relevance of 95 loci for blood lipids | Nature | 2010 | 3,300 |
| 4 | 10 Years of GWAS Discovery: Biology, Function, and Translation | American Journal of Human Genetics | 2017 | 2,965 |
| 5 | Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease | Nature Genetics | 2008 | 2,454 |
| 6 | Replication of Genome-Wide Association Signals in UK Samples Reveals Risk Loci for Type 2 Diabetes | Science | 2007 | 2,057 |
| 7 | A forkhead-domain gene is mutated in a severe speech and language disorder | Nature | 2001 | 1,995 |
| 8 | Systematic identification of trans eQTLs as putative drivers of known disease associations | Nature Genetics | 2013 | 1,577 |
| 9 | Missing heritability and strategies for finding the underlying causes of complex disease | Nature Reviews Genetics | 2010 | 1,537 |
| 10 | Mouse genomic variation and its effect on phenotypes and gene regulation | Nature | 2011 | 1,500 |
| 11 | Automated binning of microsatellite alleles: problems and solutions | Molecular Ecology Notes | 2006 | 1,417 |
| 12 | The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease | Cell | 2016 | 1,095 |
| 13 | Composition and Three-Dimensional Architecture of the Dengue Virus Replication and Assembly Sites | Cell Host and Microbe | 2009 | 914 |
| 14 | Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis | EMBO Journal | 2001 | 812 |
| 15 | Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity | Nature | 2017 | 777 |
| 16 | Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene Expression | Science | 2014 | 723 |
| 17 | A Genetic Atlas of Human Admixture History | Science | 2014 | 717 |
| 18 | Transforming clinical microbiology with bacterial genome sequencing | Nature Reviews Genetics | 2012 | 698 |
| 19 | A time- and cost-efficient system for high-level protein production in mammalian cells | Acta Crystallographica Section D: Biological Crystallography | 2006 | 694 |
| 20 | Insights into hominid evolution from the gorilla genome sequence | Nature | 2012 | 672 |
| 21 | Crystal structure of a human GABAA receptor | Nature | 2014 | 636 |
| 22 | The Genetics of Major Depression | Neuron | 2014 | 591 |
| 23 | A Humanized Version of Foxp2 Affects Cortico-Basal Ganglia Circuits in Mice | Cell | 2009 | 557 |
| 24 | HLA variation and disease | Nature Reviews Immunology | 2018 | 542 |
| 25 | Genome-wide genetic association of complex traits in heterogeneous stock mice | Nature Genetics | 2006 | 514 |
| 26 | REV7 counteracts DNA double-strand break resection and affects PARP inhibition | Nature | 2015 | 506 |
| 27 | The African Genome Variation Project shapes medical genetics in Africa | Nature | 2015 | 489 |
| 28 | The complex interplay among factors that influence allelic association | Nature Reviews Genetics | 2004 | 483 |
| 29 | FOXP2 as a molecular window into speech and language | Trends in Genetics | 2009 | 482 |
| 30 | The Fusion Glycoprotein Shell of Semliki Forest Virus | Cell | 2001 | 473 |
| 31 | The stoichiometry of Gag protein in HIV-1 | Nature Structural and Molecular Biology | 2004 | 467 |
| 32 | Strategies for mapping and cloning quantitative trait genes in rodents | Nature Reviews Genetics | 2005 | 465 |
| 33 | The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling | Nature Genetics | 2009 | 463 |
| 34 | The bonobo genome compared with the chimpanzee and human genomes | Nature | 2012 | 462 |
| 35 | Genetics of susceptibitlity to human infectious disease | Nature Reviews Genetics | 2001 | 450 |
| 36 | The fine-scale genetic structure of the British population | Nature | 2015 | 448 |
| 37 | Twin concordance and sibling recurrence rates in multiple sclerosis | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 442 |
| 38 | Clonally expanded B cells in multiple sclerosis bind EBV EBNA1 and GlialCAM | Nature | 2022 | 426 |
| 39 | A Genome-Wide Association Study Identifies Protein Quantitative Trait Loci (pQTLs) | PLoS Genetics | 2008 | 425 |
| 40 | Human genetic susceptibility to infectious disease | Nature Reviews Genetics | 2012 | 425 |
| 41 | Acoelomorph flatworms are deuterostomes related to Xenoturbella | Nature | 2011 | 408 |
| 42 | A common sequence motif associated with recombination hot spots and genome instability in humans | Nature Genetics | 2008 | 403 |
| 43 | Structural organization of authentic, mature HIV-1 virions and cores | EMBO Journal | 2003 | 395 |
| 44 | Evaluating coverage of genome-wide association studies | Nature Genetics | 2006 | 391 |
| 45 | GRR: graphical representation of relationship errors | Bioinformatics | 2001 | 380 |
| 46 | Gene polymorphism in Netherton and common atopic disease | Nature Genetics | 2001 | 378 |
| 47 | Melanopsin: an exciting photopigment | Trends in Neurosciences | 2008 | 370 |
| 48 | ATR-X Syndrome Protein Targets Tandem Repeats and Influences Allele-Specific Expression in a Size-Dependent Manner | Cell | 2010 | 370 |
| 49 | Notum deacylates Wnt proteins to suppress signalling activity | Nature | 2015 | 366 |
| 50 | A conserved sorting-associated protein is mutant in chorea-acanthocytosis | Nature Genetics | 2001 | 362 |
