# | Title | Journal | Year | Citations |
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1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
2 | Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease | Cell | 2017 | 4,081 |
3 | Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 1,970 |
4 | Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450 | Biochemical Pharmacology | 1985 | 1,255 |
5 | DNA and its associated processes as targets for cancer therapy | Nature Reviews Cancer | 2002 | 1,223 |
6 | The emerging role of the Nrf2–Keap1 signaling pathway in cancer | Genes and Development | 2013 | 1,044 |
7 | NRF2 and the Hallmarks of Cancer | Cancer Cell | 2018 | 1,016 |
8 | Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution | Nucleic Acids Research | 2006 | 1,008 |
9 | NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis | Redox Biology | 2019 | 957 |
10 | Mechanistic Studies of the Nrf2-Keap1 Signaling Pathway | Drug Metabolism Reviews | 2006 | 924 |
11 | Mitochondrial energetics in the kidney | Nature Reviews Nephrology | 2017 | 758 |
12 | Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease | Cell Research | 2020 | 662 |
13 | Measurement of Adherence in Pharmacy Administrative Databases: A Proposal for Standard Definitions and Preferred Measures | Annals of Pharmacotherapy | 2006 | 632 |
14 | A Comparative Review of Generic Quality-of-Life Instruments | Pharmacoeconomics | 2000 | 627 |
15 | Discrimination of Multiple [3H]5-Hydroxytryptamine Binding Sites by the Neuroleptic Spiperone in Rat Brain | Journal of Neurochemistry | 1981 | 622 |
16 | Molecular Evidence for a Uniform Microbial Community in Sponges from Different Oceans | Applied and Environmental Microbiology | 2002 | 621 |
17 | Drug-Related Morbidity and Mortality: Updating the Cost-of-Illness Model | Journal of the American Pharmacists Association | 2001 | 567 |
18 | Solution Structure of the Biologically Relevant G-Quadruplex Element in the Human c-MYC Promoter. Implications for G-Quadruplex Stabilization | Biochemistry | 2005 | 565 |
19 | Prevalence, determinants, and outcomes of nonadherence to imatinib therapy in patients with chronic myeloid leukemia: the ADAGIO study | Blood | 2009 | 540 |
20 | Telomestatin, a Potent Telomerase Inhibitor That Interacts Quite Specifically with the Human Telomeric Intramolecular G-Quadruplex | Journal of the American Chemical Society | 2002 | 494 |
21 | Structure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K+ solution: insights into structure polymorphism of the human telomeric sequence | Nucleic Acids Research | 2007 | 492 |
22 | Recommendations on Evidence Needed to Support Measurement Equivalence between Electronic and Paper-Based Patient-Reported Outcome (PRO) Measures: ISPOR ePRO Good Research Practices Task Force Report | Value in Health | 2009 | 430 |
23 | Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regions | Biochimie | 2008 | 415 |
24 | The Roles of NRF2 in Modulating Cellular Iron Homeostasis | Antioxidants and Redox Signaling | 2018 | 412 |
25 | Redox-Directed Cancer Therapeutics: Molecular Mechanisms and Opportunities | Antioxidants and Redox Signaling | 2009 | 409 |
26 | Making sense of G‐quadruplex and i‐motif functions in oncogene promoters | FEBS Journal | 2010 | 401 |
27 | EP2 and EP4 prostanoid receptor signaling | Life Sciences | 2003 | 382 |
28 | Polymorphism of human telomeric quadruplex structures | Biochimie | 2008 | 382 |
29 | An Intramolecular G-Quadruplex Structure with Mixed Parallel/Antiparallel G-Strands Formed in the Human BCL-2 Promoter Region in Solution | Journal of the American Chemical Society | 2006 | 374 |
30 | Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents | Nucleic Acids Research | 2005 | 367 |
31 | Identification of Sensor Cysteines in Human Keap1 Modified by the Cancer Chemopreventive Agent Sulforaphane | Chemical Research in Toxicology | 2005 | 363 |
32 | Sample preparation and digestion for proteomic analyses using spin filters | Proteomics | 2005 | 356 |
33 | The Dynamic Character of the G-Quadruplex Element in the c-MYC Promoter and Modification by TMPyP4 | Journal of the American Chemical Society | 2004 | 352 |
34 | Structure of the intramolecular human telomeric G-quadruplex in potassium solution: a novel adenine triple formation | Nucleic Acids Research | 2007 | 350 |
35 | Deconvoluting the Structural and Drug-Recognition Complexity of the G-Quadruplex-Forming Region Upstream of thebcl-2P1 Promoter | Journal of the American Chemical Society | 2006 | 345 |
36 | The Importance of Negative Superhelicity in Inducing the Formation of G-Quadruplex and i-Motif Structures in the c-Myc Promoter: Implications for Drug Targeting and Control of Gene Expression | Journal of Medicinal Chemistry | 2009 | 344 |
37 | Endogenous UVA-photosensitizers: mediators of skin photodamage and novel targets for skin photoprotection | Photochemical and Photobiological Sciences | 2006 | 343 |
38 | Telomestatin and Diseleno Sapphyrin Bind Selectively to Two Different Forms of the Human Telomeric G-Quadruplex Structure | Journal of the American Chemical Society | 2005 | 328 |
39 | NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region | Nucleic Acids Research | 2006 | 323 |
40 | The absolute bioavailability of caffeine in man | European Journal of Clinical Pharmacology | 1983 | 318 |
41 | Solution Structure of a 2:1 Quindoline–c-MYC G-Quadruplex: Insights into G-Quadruplex-Interactive Small Molecule Drug Design | Journal of the American Chemical Society | 2011 | 313 |
42 | Estimation of the aqueous solubility I: Application to organic nonelectrolytes | Journal of Pharmaceutical Sciences | 2001 | 308 |
43 | Design and Synthesis of an Expanded Porphyrin That Has Selectivity for the c-MYC G-Quadruplex Structure | Journal of the American Chemical Society | 2005 | 303 |
44 | The Role of Metabolism in the Antioxidant Function of Vitamin E | Critical Reviews in Toxicology | 1993 | 301 |
45 | Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M pro and cathepsin L | Science Advances | 2020 | 297 |
46 | Structural insights into G-quadruplexes: towards new anticancer drugs | Future Medicinal Chemistry | 2010 | 295 |
47 | Biosynthesis and attachment of novel bacterial polyketide synthase starter units | Natural Product Reports | 2002 | 292 |
48 | Tyrosine kinase receptor-activated signal transduction pathways which lead to oncogenesis | Oncogene | 1998 | 289 |
49 | Modulating NRF2 in Disease: Timing Is Everything | Annual Review of Pharmacology and Toxicology | 2019 | 289 |
50 | Specific Patterns of Electrophile Adduction Trigger Keap1 Ubiquitination and Nrf2 Activation | Journal of Biological Chemistry | 2005 | 280 |