# | Title | Journal | Year | Citations |
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1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
2 | The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses | Nature Immunology | 2010 | 1,113 |
3 | Intraclonal generation of antibody mutants in germinal centres | Nature | 1991 | 1,016 |
4 | Catalytic specificity of protein-tyrosine kinases is critical for selective signalling | Nature | 1995 | 932 |
5 | Genome evolution in the allotetraploid frog Xenopus laevis | Nature | 2016 | 849 |
6 | Elephant shark genome provides unique insights into gnathostome evolution | Nature | 2014 | 689 |
7 | Prostaglandin E2 inhibits production of Th1 lymphokines but not of Th2 lymphokines. | Journal of Immunology | 1991 | 632 |
8 | Prostaglandin E2 inhibits production of Th1 lymphokines but not of Th2 lymphokines | Journal of Immunology | 1991 | 621 |
9 | The TLR4 antagonist Eritoran protects mice from lethal influenza infection | Nature | 2013 | 382 |
10 | Cross-kingdom interactions:Candida albicansand bacteria | FEMS Microbiology Letters | 2009 | 362 |
11 | Osteomyelitis and the role of biofilms in chronic infection | FEMS Immunology and Medical Microbiology | 2008 | 322 |
12 | Life and Death in Germinal Centers (Redux) | Immunity | 1996 | 312 |
13 | Selective Roles for Toll-Like Receptor (TLR)2 and TLR4 in the Regulation of Neutrophil Activation and Life Span | Journal of Immunology | 2003 | 306 |
14 | Induction of In Vitro Reprogramming by Toll-Like Receptor (TLR)2 and TLR4 Agonists in Murine Macrophages: Effects of TLR “Homotolerance” Versus “Heterotolerance” on NF-κB Signaling Pathway Components | Journal of Immunology | 2003 | 291 |
15 | TLR4/MyD88/PI3K interactions regulate TLR4 signaling | Journal of Leukocyte Biology | 2009 | 272 |
16 | Dysregulation of LPS-Induced Toll-Like Receptor 4-MyD88 Complex Formation and IL-1 Receptor-Associated Kinase 1 Activation in Endotoxin-Tolerant Cells | Journal of Immunology | 2002 | 266 |
17 | Distinct Mutations in IRAK-4 Confer Hyporesponsiveness to Lipopolysaccharide and Interleukin-1 in a Patient with Recurrent Bacterial Infections | Journal of Experimental Medicine | 2003 | 266 |
18 | Rickettsial Infection inDermacentor variabilis(Acari: Ixodidae) Inhibits Transovarial Transmission of a SecondRickettsia | Journal of Medical Entomology | 2002 | 246 |
19 | Unique Signatures of Long Noncoding RNA Expression in Response to Virus Infection and Altered Innate Immune Signaling | MBio | 2010 | 237 |
20 | Analysis of TLR4 Polymorphic Variants: New Insights into TLR4/MD-2/CD14 Stoichiometry, Structure, and Signaling | Journal of Immunology | 2006 | 233 |
21 | Abelson Kinase Inhibitors Are Potent Inhibitors of Severe Acute Respiratory Syndrome Coronavirus and Middle East Respiratory Syndrome Coronavirus Fusion | Journal of Virology | 2016 | 229 |
22 | Host-specific induction of Escherichia coli fitness genes during human urinary tract infection | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 215 |
23 | Identification of Staphylococcus aureus Proteins Recognized by the Antibody-Mediated Immune Response to a Biofilm Infection | Infection and Immunity | 2006 | 203 |
24 | Galectins as Pattern Recognition Receptors: Structure, Function, and Evolution | Advances in Experimental Medicine and Biology | 2012 | 202 |
25 | Commensal Protection of Staphylococcus aureus against Antimicrobials by Candida albicans Biofilm Matrix | MBio | 2016 | 202 |
26 | The Translesion DNA Polymerase ζ Plays a Major Role in Ig and bcl-6 Somatic Hypermutation | Immunity | 2001 | 199 |
27 | Toll-Like Receptors in Health and Disease: Complex Questions Remain | Journal of Immunology | 2003 | 198 |
28 | Exoplanet Biosignatures: Understanding Oxygen as a Biosignature in the Context of Its Environment | Astrobiology | 2018 | 194 |
29 | IgD, like IgM, is a primordial immunoglobulin class perpetuated in most jawed vertebrates | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 193 |
30 | The CATERPILLER Protein Monarch-1 Is an Antagonist of Toll-like Receptor-, Tumor Necrosis Factor α-, and Mycobacterium tuberculosis-induced Pro-inflammatory Signals | Journal of Biological Chemistry | 2005 | 191 |
31 | Functional Heterogeneity of Marginal Zone B Cells Revealed by Their Ability to Generate Both Early Antibody-forming Cells and Germinal Centers with Hypermutation and Memory in Response to a T-dependent Antigen | Journal of Experimental Medicine | 2003 | 189 |
32 | Mechanisms of immune evasion in breast cancer | BMC Cancer | 2018 | 180 |
33 | Tobacco Smoking Inhibits Expression of Proinflammatory Cytokines and Activation of IL-1R-Associated Kinase, p38, and NF-κB in Alveolar Macrophages Stimulated with TLR2 and TLR4 Agonists | Journal of Immunology | 2007 | 170 |
34 | 5,6-Dimethylxanthenone-4-acetic Acid (DMXAA) Activates Stimulator of Interferon Gene (STING)-dependent Innate Immune Pathways and Is Regulated by Mitochondrial Membrane Potential | Journal of Biological Chemistry | 2012 | 169 |
35 | Proteus mirabilisbiofilms and catheter-associated urinary tract infections | Virulence | 2011 | 168 |
36 | LPS remodeling is an evolved survival strategy for bacteria | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 167 |
37 | Loss of heterozygosity involves multiple tumor suppressor genes in human esophageal cancers | Cancer Research | 1992 | 167 |
38 | Middle East Respiratory Syndrome and Severe Acute Respiratory Syndrome: Current Therapeutic Options and Potential Targets for Novel Therapies | Drugs | 2017 | 156 |
39 | Sustained Generation of Nitric Oxide and Control of Mycobacterial Infection Requires Argininosuccinate Synthase 1 | Cell Host and Microbe | 2012 | 154 |
40 | Pathogenesis of Proteus mirabilisurinary tract infection | Microbes and Infection | 2000 | 149 |
41 | Primitive synteny of vertebrate major histocompatibility complex class I and class II genes | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 149 |
42 | Detection of murine typhus infection in fleas by using the polymerase chain reaction | Journal of Clinical Microbiology | 1990 | 147 |
43 | Induction or prevention of immunopathological disease by cloned cytotoxic T cell lines specific for lymphocytic choriomeningitis virus | European Journal of Immunology | 1986 | 143 |
44 | Decreased Frequency of Somatic Hypermutation and Impaired Affinity Maturation but Intact Germinal Center Formation in Mice Expressing Antisense RNA to DNA Polymerase ζ | Journal of Immunology | 2001 | 141 |
45 | Antitumorigenic effects of HIV protease inhibitor ritonavir: inhibition of Kaposi sarcoma | Blood | 2002 | 140 |
46 | Contribution of Interferon-β to the Murine Macrophage Response to the Toll-like Receptor 4 Agonist, Lipopolysaccharide | Journal of Biological Chemistry | 2006 | 139 |
47 | The DNA Sensor, Cyclic GMP–AMP Synthase, Is Essential for Induction of IFN-β during Chlamydia trachomatis Infection | Journal of Immunology | 2014 | 139 |
48 | Exoplanet Biosignatures: A Framework for Their Assessment | Astrobiology | 2018 | 139 |
49 | Novel signaling interactions between proteinase-activated receptor 2 and Toll-like receptors in vitro and in vivo | Mucosal Immunology | 2010 | 138 |
50 | The chemotherapeutic agent DMXAA potently and specifically activates the TBK1–IRF-3 signaling axis | Journal of Experimental Medicine | 2007 | 137 |