| # | Title | Journal | Year | Citations |
|---|
|
| 1 | Nonparametric Analysis of Statistic Images from Functional Mapping Experiments | Journal of Cerebral Blood Flow and Metabolism | 1996 | 810 |
| 2 | Staging Presymptomatic Type 1 Diabetes: A Scientific Statement of JDRF, the Endocrine Society, and the American Diabetes Association | Diabetes Care | 2015 | 740 |
| 3 | An Anti-CD3 Antibody, Teplizumab, in Relatives at Risk for Type 1 Diabetes | New England Journal of Medicine | 2019 | 665 |
| 4 | An alternative method for significance testing of waveform difference potentials | Psychophysiology | 1993 | 566 |
| 5 | Type 2 Diabetes as a Risk Factor for Dementia in Women Compared With Men: A Pooled Analysis of 2.3 Million People Comprising More Than 100,000 Cases of Dementia | Diabetes Care | 2016 | 488 |
| 6 | Mortality Resulting From Congenital Heart Disease Among Children and Adults in the United States, 1999 to 2006 | Circulation | 2010 | 484 |
| 7 | Fruit and Vegetable Juices and Alzheimer’s Disease: The Kame Project | American Journal of Medicine | 2006 | 457 |
| 8 | Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure | Nature Genetics | 2011 | 407 |
| 9 | Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer | Nature Genetics | 2017 | 395 |
| 10 | Sleep, Cognitive impairment, and Alzheimer’s disease: A Systematic Review and Meta-Analysis | Sleep | 2017 | 385 |
| 11 | Cancer and lesbian, gay, bisexual, transgender/transsexual, and queer/questioning (LGBTQ) populations | Ca-A Cancer Journal for Clinicians | 2015 | 382 |
| 12 | A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24 | Nature Genetics | 2010 | 325 |
| 13 | The burden of neurological disease in theUnitedStates: A summary report and call to action | Annals of Neurology | 2017 | 306 |
| 14 | Epidemiology of prenatal smoking and perinatal outcomes | Early Human Development | 2007 | 287 |
| 15 | Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders | Nature Genetics | 2013 | 286 |
| 16 | Impaired olfaction as a marker for cognitive decline | Neurology | 1999 | 285 |
| 17 | Insomnia and heart disease | Journal of Psychosomatic Research | 1999 | 283 |
| 18 | Risk of Pediatric Celiac Disease According to HLA Haplotype and Country | New England Journal of Medicine | 2014 | 283 |
| 19 | CMT subtypes and disease burden in patients enrolled in the Inherited Neuropathies Consortium natural history study: a cross-sectional analysis | Journal of Neurology, Neurosurgery and Psychiatry | 2015 | 267 |
| 20 | The Epidemiology of Childhood Psychiatric Disorders: Prevalence Findings from Recent Studies | Journal of the American Academy of Child and Adolescent Psychiatry | 1990 | 257 |
| 21 | Obstructive Sleep Apnea and Severe Maternal-Infant Morbidity/Mortality in the United States, 1998-2009 | Sleep | 2014 | 237 |
| 22 | Standardizing Nasal Nitric Oxide Measurement as a Test for Primary Ciliary Dyskinesia | Annals of the American Thoracic Society | 2013 | 230 |
| 23 | Early-Life Risk Factors for Alzheimer Disease | Alzheimer Disease and Associated Disorders | 2006 | 227 |
| 24 | Prevalence of Dementia and Its Subtypes in the Japanese American Population of King County, Washington State: The Kame Project | American Journal of Epidemiology | 1996 | 226 |
| 25 | Pancreatic Islet Autoantibodies as Predictors of Type 1 Diabetes in the Diabetes Prevention Trial–Type 1 | Diabetes Care | 2009 | 226 |
| 26 | Changes in Brain Volume and Cognition in a Randomized Trial of Exercise and Social Interaction in a Community-Based Sample of Non-Demented Chinese Elders | Journal of Alzheimer's Disease | 2012 | 221 |
| 27 | Immigration Generation Status and its Association with Suicide Attempts, Substance Use, and Depressive Symptoms among Latino Adolescents in the USA | Prevention Science | 2008 | 209 |
| 28 | Obstructive sleep apnea, cognition and Alzheimer's disease: A systematic review integrating three decades of multidisciplinary research | Sleep Medicine Reviews | 2020 | 208 |
| 29 | What Threshold for Adjuvant Therapy in Older Breast Cancer Patients? | Journal of Clinical Oncology | 2000 | 203 |
| 30 | The intermediate endpoint effect in logistic and probit regression | Clinical Trials | 2007 | 203 |
| 31 | Association between late-life body mass index and dementia | Neurology | 2009 | 201 |
| 32 | Association of Maternal Body Mass Index, Excessive Weight Gain, and Gestational Diabetes Mellitus With Large-for-Gestational-Age Births | Obstetrics and Gynecology | 2014 | 196 |
| 33 | The Environmental Determinants of Diabetes in the Young (TEDDY): genetic criteria and international diabetes risk screening of 421 000 infants | Pediatric Diabetes | 2011 | 191 |
| 34 | Potentially modifiable risk factors for dementia in identical twins | Alzheimer's and Dementia | 2006 | 190 |
| 35 | Hierarchical Bayesian Methods for Estimation of Parameters in a Longitudinal HIV Dynamic System | Biometrics | 2006 | 190 |
| 36 | Obstructive Sleep Apnea Severity Affects Amyloid Burden in Cognitively Normal Elderly. A Longitudinal Study | American Journal of Respiratory and Critical Care Medicine | 2018 | 183 |
| 37 | PALB2,CHEK2andATMrare variants and cancer risk: data from COGS | Journal of Medical Genetics | 2016 | 179 |
| 38 | A systems view of mother–infant face-to-face communication. | Developmental Psychology | 2016 | 179 |
| 39 | BST-CarGel® Treatment Maintains Cartilage Repair Superiority over Microfracture at 5 Years in a Multicenter Randomized Controlled Trial | Cartilage | 2015 | 174 |
| 40 | Teplizumab improves and stabilizes beta cell function in antibody-positive high-risk individuals | Science Translational Medicine | 2021 | 172 |
| 41 | Serum VEGF-D concentration as a biomarker of lymphangioleiomyomatosis severity and treatment response: a prospective analysis of the Multicenter International Lymphangioleiomyomatosis Efficacy of Sirolimus (MILES) trial | Lancet Respiratory Medicine,the | 2013 | 161 |
| 42 | Prevalence of mild cognitive impairment in an urban community in China: A cross‐sectional analysis of the Shanghai Aging Study | Alzheimer's and Dementia | 2015 | 159 |
| 43 | The epidemiology of aplastic anemia in Thailand | Blood | 2006 | 158 |
| 44 | Prenatal Diagnosis, Birth Location, Surgical Center, and Neonatal Mortality in Infants With Hypoplastic Left Heart Syndrome | Circulation | 2014 | 157 |
| 45 | Very Early Detection of Alzheimer Neuropathology and the Role of Brain Reserve in Modifying Its Clinical Expression | Journal of Geriatric Psychiatry and Neurology | 2005 | 154 |
| 46 | Methods for testing theory and evaluating impact in randomized field trials: Intent-to-treat analyses for integrating the perspectives of person, place, and time | Drug and Alcohol Dependence | 2008 | 154 |
| 47 | Head Circumference as a Measure of Cognitive Reserve | British Journal of Psychiatry | 1996 | 146 |
| 48 | Association of exposure to diabetes in utero with adiposity and fat distribution in a multiethnic population of youth: the Exploring Perinatal Outcomes among Children (EPOCH) Study | Diabetologia | 2011 | 146 |
| 49 | Association between type 2 diabetes and risk of cancer mortality: a pooled analysis of over 771,000 individuals in the Asia Cohort Consortium | Diabetologia | 2017 | 145 |
| 50 | Reduced Prevalence of Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes in Young Children Participating in Longitudinal Follow-Up | Diabetes Care | 2011 | 144 |
