| # | Title | Journal | Year | Citations |
|---|
| 1 | Drug repurposing: progress, challenges and recommendations | Nature Reviews Drug Discovery | 2019 | 2,689 |
| 2 | ProteomeXchange provides globally coordinated proteomics data submission and dissemination | Nature Biotechnology | 2014 | 2,505 |
| 3 | Present and Future of Surface-Enhanced Raman Scattering | ACS Nano | 2020 | 2,153 |
| 4 | Hybridization and speciation | Journal of Evolutionary Biology | 2013 | 1,735 |
| 5 | The power of ion mobility-mass spectrometry for structural characterization and the study of conformational dynamics | Nature Chemistry | 2014 | 753 |
| 6 | Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations | Nucleic Acids Research | 2015 | 693 |
| 7 | Taxonomic assignment of uncultivated prokaryotic virus genomes is enabled by gene-sharing networks | Nature Biotechnology | 2019 | 569 |
| 8 | A rapid method to estimate the concentration of citrate capped silver nanoparticles from UV-visible light spectra | Analyst, The | 2014 | 548 |
| 9 | The biology of color | Science | 2017 | 509 |
| 10 | The 27th annual Nucleic Acids Research database issue and molecular biology database collection | Nucleic Acids Research | 2020 | 470 |
| 11 | Taming anxiety in laboratory mice | Nature Methods | 2010 | 467 |
| 12 | Human Ageing Genomic Resources: Integrated databases and tools for the biology and genetics of ageing | Nucleic Acids Research | 2012 | 467 |
| 13 | Circulating Histones Are Mediators of Trauma-associated Lung Injury | American Journal of Respiratory and Critical Care Medicine | 2013 | 463 |
| 14 | Urbanization and Disease Emergence: Dynamics at the Wildlife–Livestock–Human Interface | Trends in Ecology and Evolution | 2017 | 455 |
| 15 | An Infection-Relevant Transcriptomic Compendium for Salmonella enterica Serovar Typhimurium | Cell Host and Microbe | 2013 | 427 |
| 16 | Improved reference genome of Aedes aegypti informs arbovirus vector control | Nature | 2018 | 426 |
| 17 | The multifactorial role of neutrophils in rheumatoid arthritis | Nature Reviews Rheumatology | 2014 | 414 |
| 18 | Minimum Information about an Uncultivated Virus Genome (MIUViG) | Nature Biotechnology | 2019 | 414 |
| 19 | A comprehensive benchmarking study of protocols and sequencing platforms for 16S rRNA community profiling | BMC Genomics | 2016 | 387 |
| 20 | The industrial melanism mutation in British peppered moths is a transposable element | Nature | 2016 | 386 |
| 21 | Warming-induced reductions in body size are greater in aquatic than terrestrial species | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 382 |
| 22 | Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools | Nucleic Acids Research | 2020 | 352 |
| 23 | Deubiquitylases From Genes to Organism | Physiological Reviews | 2013 | 350 |
| 24 | Contribution of trans regulatory eQTL to cryptic genetic variation in C. elegans | BMC Genomics | 2017 | 345 |
| 25 | Inclusive fitness theory and eusociality | Nature | 2011 | 339 |
| 26 | Why infectious disease research needs community ecology | Science | 2015 | 330 |
| 27 | How to Name and Classify Your Phage: An Informal Guide | Viruses | 2017 | 323 |
| 28 | Nanopore direct RNA sequencing maps the complexity of Arabidopsis mRNA processing and m6A modification | ELife | 2020 | 312 |
| 29 | FungiDB: An Integrated Bioinformatic Resource for Fungi and Oomycetes | Journal of Fungi (Basel, Switzerland) | 2018 | 309 |
| 30 | The Role of DNA Methylation in Aging, Rejuvenation, and Age-Related Disease | Rejuvenation Research | 2012 | 307 |
| 31 | The Ecology and Evolutionary Dynamics of Meiotic Drive | Trends in Ecology and Evolution | 2016 | 305 |
| 32 | Root gravitropism is regulated by a transient lateral auxin gradient controlled by a tipping-point mechanism | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 304 |
| 33 | Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling | Genome Biology | 2013 | 296 |
| 34 | Marked seasonal variation in the wild mouse gut microbiota | ISME Journal | 2015 | 282 |
| 35 | Plasmid-mediated horizontal gene transfer is a coevolutionary process | Trends in Microbiology | 2012 | 280 |
| 36 | How ageing processes influence cancer | Nature Reviews Cancer | 2013 | 280 |
| 37 | Insights into the Evolution of Longevity from the Bowhead Whale Genome | Cell Reports | 2015 | 280 |
| 38 | Temporal and spatial analysis of the 2014–2015 Ebola virus outbreak in West Africa | Nature | 2015 | 272 |
| 39 | Hypoxia induces rapid changes to histone methylation and reprograms chromatin | Science | 2019 | 266 |
| 40 | The Fibrobacteres: an Important Phylum of Cellulose-Degrading Bacteria | Microbial Ecology | 2012 | 255 |
| 41 | Nanoparticles for Imaging, Sensing, and Therapeutic Intervention | ACS Nano | 2014 | 255 |
| 42 | The Biology of Lactoferrin, an Iron-Binding Protein That Can Help Defend Against Viruses and Bacteria | Frontiers in Immunology | 2020 | 251 |
| 43 | Application of next-generation sequencing technologies in virology | Journal of General Virology | 2012 | 241 |
| 44 | A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties | Biochemical Journal | 2014 | 241 |
| 45 | The diversity-generating benefits of a prokaryotic adaptive immune system | Nature | 2016 | 236 |
| 46 | Genomic determinants of sporulation in Bacilli and Clostridia: towards the minimal set of sporulation‐specific genes | Environmental Microbiology | 2012 | 235 |
| 47 | Rapid evolution of thermal tolerance in the water flea Daphnia | Nature Climate Change | 2015 | 230 |
| 48 | Growing a circular economy with fungal biotechnology: a white paper | Fungal Biology and Biotechnology | 2020 | 228 |
| 49 | Running with the Red Queen: the role of biotic conflicts in evolution | Proceedings of the Royal Society B: Biological Sciences | 2014 | 225 |
| 50 | Parallel Compensatory Evolution Stabilizes Plasmids across the Parasitism-Mutualism Continuum | Current Biology | 2015 | 225 |
