# | Title | Journal | Year | Citations |
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|
1 | A revolution in optical manipulation | Nature | 2003 | 4,706 |
2 | N6-methyladenosine-dependent regulation of messenger RNA stability | Nature | 2014 | 3,328 |
3 | N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO | Nature Chemical Biology | 2011 | 3,118 |
4 | ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility | Molecular Cell | 2013 | 2,708 |
5 | N6-methyladenosine Modulates Messenger RNA Translation Efficiency | Cell | 2015 | 2,609 |
6 | A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation | Nature Chemical Biology | 2014 | 2,490 |
7 | Dynamic RNA Modifications in Gene Expression Regulation | Cell | 2017 | 2,424 |
8 | Single-molecule mechanics of mussel adhesion | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 1,868 |
9 | Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation | Nature Cell Biology | 2018 | 1,836 |
10 | Post-transcriptional gene regulation by mRNA modifications | Nature Reviews Molecular Cell Biology | 2017 | 1,715 |
11 | Reactions in Droplets in Microfluidic Channels | Angewandte Chemie - International Edition | 2006 | 1,667 |
12 | Global Epigenomic Reconfiguration During Mammalian Brain Development | Science | 2013 | 1,645 |
13 | N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions | Nature | 2015 | 1,574 |
14 | Gene expression regulation mediated through reversible m6A RNA methylation | Nature Reviews Genetics | 2014 | 1,485 |
15 | pH-induced metal-ligand cross-links inspired by mussel yield self-healing polymer networks with near-covalent elastic moduli | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 1,364 |
16 | YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA | Cell Research | 2017 | 1,333 |
17 | Where, When, and How: Context-Dependent Functions of RNA Methylation Writers, Readers, and Erasers | Molecular Cell | 2019 | 1,213 |
18 | FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N 6 -Methyladenosine RNA Demethylase | Cancer Cell | 2017 | 1,197 |
19 | m 6 A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program | Cancer Cell | 2017 | 1,182 |
20 | Protein Nanoarrays Generated By Dip-Pen Nanolithography | Science | 2002 | 1,165 |
21 | Tet2 Loss Leads to Increased Hematopoietic Stem Cell Self-Renewal and Myeloid Transformation | Cancer Cell | 2011 | 1,137 |
22 | Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism | Cell Research | 2018 | 1,137 |
23 | m 6 A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells | Cell Reports | 2017 | 1,070 |
24 | Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine | Nature Biotechnology | 2011 | 974 |
25 | Base-Resolution Analysis of 5-Hydroxymethylcytosine in the Mammalian Genome | Cell | 2012 | 934 |
26 | FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis | Cell Research | 2014 | 930 |
27 | YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs | ELife | 2017 | 889 |
28 | Total chemical synthesis of proteins | Chemical Society Reviews | 2009 | 856 |
29 | R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling | Cell | 2018 | 855 |
30 | Mechanical Integration of Actin and Adhesion Dynamics in Cell Migration | Annual Review of Cell and Developmental Biology | 2010 | 845 |
31 | RNA modifications modulate gene expression during development | Science | 2018 | 837 |
32 | The charge of glass and silica surfaces | Journal of Chemical Physics | 2001 | 807 |
33 | The dynamic N1-methyladenosine methylome in eukaryotic messenger RNA | Nature | 2016 | 804 |
34 | METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification | Cell Stem Cell | 2018 | 793 |
35 | RNA N6-methyladenosine methylation in post-transcriptional gene expression regulation | Genes and Development | 2015 | 769 |
36 | 5-hmC–mediated epigenetic dynamics during postnatal neurodevelopment and aging | Nature Neuroscience | 2011 | 760 |
37 | Ythdc2 is an N6-methyladenosine binding protein that regulates mammalian spermatogenesis | Cell Research | 2017 | 752 |
38 | Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells | Nature | 2019 | 732 |
39 | Stress-Triggered Phase Separation Is an Adaptive, Evolutionarily Tuned Response | Cell | 2017 | 726 |
40 | VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation | Cell Discovery | 2018 | 705 |
41 | Peptide chips for the quantitative evaluation of protein kinase activity | Nature Biotechnology | 2002 | 701 |
42 | Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal | Molecular Cell | 2018 | 667 |
43 | Random-coil behavior and the dimensions of chemically unfolded proteins | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 637 |
44 | DNA Methylation on N6-Adenine in C. elegans | Cell | 2015 | 623 |
45 | m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer | Nature Cell Biology | 2018 | 622 |
46 | Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation | Cell | 2017 | 600 |
47 | Structure of Optical Vortices | Physical Review Letters | 2003 | 595 |
48 | N6-Methyladenine DNA Modification in Drosophila | Cell | 2015 | 591 |
49 | Structural basis for selective binding of m6A RNA by the YTHDC1 YTH domain | Nature Chemical Biology | 2014 | 583 |
50 | Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia | Cancer Cell | 2019 | 575 |