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Top Articles

#TitleJournalYearCitations
1A revolution in optical manipulationNature20034,706
2N6-methyladenosine-dependent regulation of messenger RNA stabilityNature20143,328
3N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTONature Chemical Biology20113,118
4ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse FertilityMolecular Cell20132,708
5N6-methyladenosine Modulates Messenger RNA Translation EfficiencyCell20152,609
6A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylationNature Chemical Biology20142,490
7Dynamic RNA Modifications in Gene Expression RegulationCell20172,424
8Single-molecule mechanics of mussel adhesionProceedings of the National Academy of Sciences of the United States of America20061,868
9Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translationNature Cell Biology20181,836
10Post-transcriptional gene regulation by mRNA modificationsNature Reviews Molecular Cell Biology20171,715
11Reactions in Droplets in Microfluidic ChannelsAngewandte Chemie - International Edition20061,667
12Global Epigenomic Reconfiguration During Mammalian Brain DevelopmentScience20131,645
13N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactionsNature20151,574
14Gene expression regulation mediated through reversible m6A RNA methylationNature Reviews Genetics20141,485
15pH-induced metal-ligand cross-links inspired by mussel yield self-healing polymer networks with near-covalent elastic moduliProceedings of the National Academy of Sciences of the United States of America20111,364
16YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNACell Research20171,333
17Where, When, and How: Context-Dependent Functions of RNA Methylation Writers, Readers, and ErasersMolecular Cell20191,213
18FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N 6 -Methyladenosine RNA DemethylaseCancer Cell20171,197
19m 6 A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation ProgramCancer Cell20171,182
20Protein Nanoarrays Generated By Dip-Pen NanolithographyScience20021,165
21Tet2 Loss Leads to Increased Hematopoietic Stem Cell Self-Renewal and Myeloid TransformationCancer Cell20111,137
22Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolismCell Research20181,137
23m 6 A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem CellsCell Reports20171,070
24Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosineNature Biotechnology2011974
25Base-Resolution Analysis of 5-Hydroxymethylcytosine in the Mammalian GenomeCell2012934
26FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesisCell Research2014930
27YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAsELife2017889
28Total chemical synthesis of proteinsChemical Society Reviews2009856
29R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA SignalingCell2018855
30Mechanical Integration of Actin and Adhesion Dynamics in Cell MigrationAnnual Review of Cell and Developmental Biology2010845
31RNA modifications modulate gene expression during developmentScience2018837
32The charge of glass and silica surfacesJournal of Chemical Physics2001807
33The dynamic N1-methyladenosine methylome in eukaryotic messenger RNANature2016804
34METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A ModificationCell Stem Cell2018793
35RNA N6-methyladenosine methylation in post-transcriptional gene expression regulationGenes and Development2015769
365-hmC–mediated epigenetic dynamics during postnatal neurodevelopment and agingNature Neuroscience2011760
37Ythdc2 is an N6-methyladenosine binding protein that regulates mammalian spermatogenesisCell Research2017752
38Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cellsNature2019732
39Stress-Triggered Phase Separation Is an Adaptive, Evolutionarily Tuned ResponseCell2017726
40VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylationCell Discovery2018705
41Peptide chips for the quantitative evaluation of protein kinase activityNature Biotechnology2002701
42Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-RenewalMolecular Cell2018667
43Random-coil behavior and the dimensions of chemically unfolded proteinsProceedings of the National Academy of Sciences of the United States of America2004637
44DNA Methylation on N6-Adenine in C. elegansCell2015623
45m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancerNature Cell Biology2018622
46Temporal Control of Mammalian Cortical Neurogenesis by m6A MethylationCell2017600
47Structure of Optical VorticesPhysical Review Letters2003595
48N6-Methyladenine DNA Modification in DrosophilaCell2015591
49Structural basis for selective binding of m6A RNA by the YTHDC1 YTH domainNature Chemical Biology2014583
50Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid LeukemiaCancer Cell2019575