| # | Title | Journal | Year | Citations |
|---|
|
| 1 | Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 2,223 |
| 2 | Low intensity transcranial electric stimulation: Safety, ethical, legal regulatory and application guidelines | Clinical Neurophysiology | 2017 | 847 |
| 3 | Albuminuria, a Therapeutic Target for Cardiovascular Protection in Type 2 Diabetic Patients With Nephropathy | Circulation | 2004 | 688 |
| 4 | Safety and recommendations for TMS use in healthy subjects and patient populations, with updates on training, ethical and regulatory issues: Expert Guidelines | Clinical Neurophysiology | 2021 | 673 |
| 5 | Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects | Clinical Pharmacology and Therapeutics | 2001 | 639 |
| 6 | Sustained Virologic Response and Clinical Outcomes in Patients with Chronic Hepatitis C and Advanced Fibrosis | Annals of Internal Medicine | 2007 | 542 |
| 7 | Pharmacokinetic interaction of digoxin with an herbal extract from St John's wort (Hypericum perforatum)*1 | Clinical Pharmacology and Therapeutics | 1999 | 534 |
| 8 | Prior Statin Therapy Is Associated With a Decreased Rate of Severe Sepsis | Circulation | 2004 | 370 |
| 9 | Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology | European Journal of Heart Failure | 2011 | 355 |
| 10 | Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study | Lancet Diabetes and Endocrinology,the | 2014 | 329 |
| 11 | Association between the C3435T MDR1 gene polymorphism and susceptibility for ulcerative colitis | Gastroenterology | 2003 | 310 |
| 12 | The Effects of Genetic Polymorphisms in the Organic Cation Transporters OCT1, OCT2, and OCT3 on the Renal Clearance of Metformin | Clinical Pharmacology and Therapeutics | 2009 | 294 |
| 13 | Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene | Clinical Pharmacology and Therapeutics | 2002 | 279 |
| 14 | Evidence for inverse effects of OATP-C (SLC21A6) *5 and *1b haplotypes on pravastatin kinetics | Clinical Pharmacology and Therapeutics | 2004 | 256 |
| 15 | Patient-Tailored Antiemetic Treatment With 5-Hydroxytryptamine Type 3 Receptor Antagonists According to Cytochrome P-450 2D6 Genotypes | Journal of Clinical Oncology | 2002 | 239 |
| 16 | Engineering Myocardial Tissue | Circulation Research | 2005 | 238 |
| 17 | Bupropion and 4-OH-bupropion pharmacokinetics in relation to genetic polymorphisms in CYP2B6 | Pharmacogenetics and Genomics | 2003 | 237 |
| 18 | Molecular Subsets of Mantle Cell Lymphoma Defined by the IGHV Mutational Status and SOX11 Expression Have Distinct Biologic and Clinical Features | Cancer Research | 2012 | 237 |
| 19 | Pharmacokinetics of tacrolimus in liver transplant patients* | Clinical Pharmacology and Therapeutics | 1995 | 219 |
| 20 | Critical Evaluation of the Effect of Valerian Extract on Sleep Structure and Sleep Quality | Pharmacopsychiatry | 2000 | 210 |
| 21 | The Role of Pharmacogenetics in the Disposition of and Response to Tacrolimus in Solid Organ Transplantation | Clinical Pharmacokinetics | 2014 | 196 |
| 22 | Toxicity of Quinolones | Drugs | 1999 | 190 |
| 23 | FGF23 is independently associated with vascular calcification but not bone mineral density in patients at various CKD stages | Osteoporosis International | 2012 | 186 |
| 24 | Impact of CYP2C9 amino acid polymorphisms on glyburide kinetics and on the insulin and glucose response in healthy volunteers | Clinical Pharmacology and Therapeutics | 2002 | 185 |
| 25 | Effect of Genetic Polymorphisms in Cytochrome P450 (CYP) 2C9 and CYP2C8 on the Pharmacokinetics of Oral Antidiabetic Drugs | Clinical Pharmacokinetics | 2005 | 181 |
| 26 | Doxazosin in the Treatment of Benign Prostatic Hyperplasia in Normotensive Patients: A Multicenter Study | Journal of Urology | 1995 | 179 |
| 27 | Impact of CYP2C9 and CYP2C19 polymorphisms on tolbutamide kinetics and the insulin and glucose response in healthy volunteers | Pharmacogenetics and Genomics | 2002 | 175 |
| 28 | The impact of the CYP2D6 polymorphism on haloperidol pharmacokinetics and on the outcome of haloperidol treatment | Clinical Pharmacology and Therapeutics | 2002 | 174 |
| 29 | Apoptosis inhibitor of macrophage protein enhances intraluminal debris clearance and ameliorates acute kidney injury in mice | Nature Medicine | 2016 | 172 |
| 30 | Intra-patient variability in tacrolimus exposure: Causes, consequences for clinical management | Transplantation Reviews | 2015 | 171 |
| 31 | Titration to target dose of bisoprolol vs. carvedilol in elderly patients with heart failure: the CIBIS-ELD trial | European Journal of Heart Failure | 2011 | 161 |
| 32 | Graft-derived cell-free DNA, a noninvasive early rejection and graft damage marker in liver transplantation: A prospective, observational, multicenter cohort study | PLoS Medicine | 2017 | 161 |
| 33 | Impact of St John's wort treatment on the pharmacokinetics of tacrolimus and mycophenolic acid in renal transplant patients | Nephrology Dialysis Transplantation | 2003 | 159 |
| 34 | Induction of Heat Shock Response Protects the Heart Against Atrial Fibrillation | Circulation Research | 2006 | 159 |
| 35 | Genetic variability of drug-metabolizing enzymes: the dual impact on psychiatric therapy and regulation of brain function | Molecular Psychiatry | 2013 | 159 |
| 36 | Nonsense-Mediated mRNA Decay and Ubiquitin–Proteasome System Regulate Cardiac Myosin-Binding Protein C Mutant Levels in Cardiomyopathic Mice | Circulation Research | 2009 | 157 |
| 37 | Decreased Plasma Levels of Amitriptyline and Its Metabolites on Comedication With an Extract From St. John’s Wort (Hypericum perforatum) | Journal of Clinical Psychopharmacology | 2002 | 152 |
| 38 | Variations in the 5-Hydroxytryptamine Type 3B Receptor Gene as Predictors of the Efficacy of Antiemetic Treatment in Cancer Patients | Journal of Clinical Oncology | 2003 | 147 |
| 39 | Increase in cerivastatin systemic exposure after single and multiple dosing in cyclosporine-treated kidney transplant recipients | Clinical Pharmacology and Therapeutics | 1999 | 146 |
| 40 | Within-host evolution of SARS-CoV-2 in an immunosuppressed COVID-19 patient as a source of immune escape variants | Nature Communications | 2021 | 146 |
| 41 | Risk Factors for Heart Failure in Patients With Type 2 Diabetes Mellitus and Stage 4 Chronic Kidney Disease Treated With Bardoxolone Methyl | Journal of Cardiac Failure | 2014 | 141 |
| 42 | Absolute quantification of donor-derived cell-free DNA as a marker of rejection and graft injury in kidney transplantation: Results from a prospective observational study | American Journal of Transplantation | 2019 | 141 |
| 43 | An Update on the Therapeutic Orphan | Pediatrics | 1999 | 139 |
| 44 | Pharmacokinetic dosing of aminoglycosides: a controlled trial | American Journal of Medicine | 2003 | 138 |
| 45 | Evidence of Gene–Environment Interactions between Common Breast Cancer Susceptibility Loci and Established Environmental Risk Factors | PLoS Genetics | 2013 | 138 |
| 46 | The predictive value of MDR1, CYP2C9, and CYP2C19 polymorphisms for phenytoin plasma levels | Pharmacogenomics Journal | 2001 | 134 |
| 47 | The validity of screening based on spot morning urine samples to detect subjects with microalbuminuria in the general population | Kidney International | 2005 | 134 |
| 48 | Effects of OCT1 polymorphisms on the cellular uptake, plasma concentrations and efficacy of the 5-HT3 antagonists tropisetron and ondansetron | Pharmacogenomics Journal | 2012 | 133 |
| 49 | Homoarginine Levels Are Regulated by l -Arginine:Glycine Amidinotransferase and Affect Stroke Outcome | Circulation | 2013 | 132 |
| 50 | Use of antiepileptic drugs in epilepsy and the risk of self-harm or suicidal behavior | Neurology | 2010 | 130 |
