| # | Title | Journal | Year | Citations |
|---|
|
| 1 | In vitro production of functional sperm in cultured neonatal mouse testes | Nature | 2011 | 651 |
| 2 | Promotion of Bladder Cancer Development and Progression by Androgen Receptor Signals | Journal of the National Cancer Institute | 2007 | 361 |
| 3 | Structural Analyses of DNA Recognition by the AML1/Runx-1 Runt Domain and Its Allosteric Control by CBFβ | Cell | 2001 | 319 |
| 4 | Transplantation of male germ line stem cells restores fertility in infertile mice | Nature Medicine | 2000 | 318 |
| 5 | VHL Tumor Suppressor Gene Alterations Associated With Good Prognosis in Sporadic Clear-Cell Renal Carcinoma | Journal of the National Cancer Institute | 2002 | 218 |
| 6 | Sperm cryopreservation before cancer chemotherapy helps in the emotional battle against cancer | Cancer | 2005 | 206 |
| 7 | In vitro production of fertile sperm from murine spermatogonial stem cell lines | Nature Communications | 2011 | 204 |
| 8 | Neonatal lethality with abnormal neurogenesis in mice deficient in DNA polymerase beta | EMBO Journal | 2000 | 201 |
| 9 | Comprehensive mutational analysis of theVHL gene in sporadic renal cell carcinoma: Relationship to clinicopathological parameters | Genes Chromosomes and Cancer | 2002 | 198 |
| 10 | Photokilling of T-24 human bladder cancer cells with titanium dioxide | British Journal of Cancer | 1994 | 189 |
| 11 | Receptor for advanced glycation end products (RAGE) and its ligand, amphoterin are overexpressed and associated with prostate cancer development | Prostate | 2005 | 189 |
| 12 | Genome-wide methylation analysis identifies epigenetically inactivated candidate tumour suppressor genes in renal cell carcinoma | Oncogene | 2011 | 173 |
| 13 | Gene expression analysis of renal carcinoma: adipose differentiation-related protein as a potential diagnostic and prognostic biomarker for clear-cell renal carcinoma | Journal of Pathology | 2005 | 168 |
| 14 | Ureteral Stent Encrustation, Incrustation, and Coloring: Morbidity Related to Indwelling Times | Journal of Endourology | 2012 | 164 |
| 15 | MEK Kinase Is Involved in Tumor Necrosis Factor α-Induced NF-κB Activation and Degradation of IκB-α | Journal of Biological Chemistry | 1996 | 162 |
| 16 | Mechanism of c-Myb–C/EBPβ Cooperation from Separated Sites on a Promoter | Cell | 2002 | 157 |
| 17 | Cyclin D2 Overexpression and Lack of p27 Correlate Positively and Cyclin E Inversely with a Poor Prognosis in Gastric Cancer Cases | American Journal of Pathology | 2000 | 152 |
| 18 | Long-term ex vivo maintenance of testis tissues producing fertile sperm in a microfluidic device | Scientific Reports | 2016 | 152 |
| 19 | Prostate cancer: a comparative study of 11C-choline PET and MR imaging combined with proton MR spectroscopy | European Journal of Nuclear Medicine and Molecular Imaging | 2005 | 150 |
| 20 | Acidic Extracellular pH Induces Matrix Metalloproteinase-9 Expression in Mouse Metastatic Melanoma Cells through the Phospholipase D-Mitogen-activated Protein Kinase Signaling | Journal of Biological Chemistry | 2005 | 148 |
| 21 | Photocatalytic inactivation of influenza virus by titanium dioxide thin film | Photochemical and Photobiological Sciences | 2012 | 145 |
| 22 | Identification of candidate tumour suppressor genes frequently methylated in renal cell carcinoma | Oncogene | 2010 | 144 |
| 23 | Offspring production with sperm grown in vitro from cryopreserved testis tissues | Nature Communications | 2014 | 144 |
| 24 | Oligo-astheno-teratozoospermia in mice lacking Cnot7, a regulator of retinoid X receptor beta | Nature Genetics | 2004 | 128 |
| 25 | Comparison of the antiviral effect of solid-state copper and silver compounds | Journal of Hazardous Materials | 2016 | 119 |
| 26 | Direct Electrochemical Oxidation of Disulfides at Anodically Pretreated Boron-Doped Diamond Electrodes | Analytical Chemistry | 2003 | 115 |
| 27 | Telomerase Activity in Primary Prostate Cancer | Journal of Urology | 1997 | 110 |
| 28 | Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers | Oncogene | 2002 | 106 |
| 29 | Self‐sterilization using silicone catheters coated with Ag and TiO2 nanocomposite thin film | Journal of Biomedical Materials Research - Part B Applied Biomaterials | 2008 | 105 |
| 30 | Androgen deprivation therapy prevents bladder cancer recurrence | Oncotarget | 2014 | 102 |
| 31 | Retinoblastoma gene mutations in primary human prostate cancer | Prostate | 1995 | 97 |
| 32 | Loss of von Hippel-Lindau protein causes cell density dependent deregulation of CyclinD1 expression through Hypoxia-inducible factor | Oncogene | 2003 | 97 |
| 33 | TRANSARTERIAL EMBOLIZATION AND ABLATION OF RENAL ARTERIOVENOUS MALFORMATIONS: EFFICACY AND DAMAGES IN 30 PATIENTS WITH LONG-TERM FOLLOWUP | Journal of Urology | 1998 | 96 |
| 34 | Expansion of Murine Spermatogonial Stem Cells Through Serial Transplantation1 | Biology of Reproduction | 2003 | 93 |
| 35 | Broad Spectrum Microbicidal Activity of Photocatalysis by TiO2 | Catalysts | 2013 | 93 |
| 36 | Impact of maximum Standardized Uptake Value (SUVmax) evaluated by 18-Fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (18F-FDG-PET/CT) on survival for patients with advanced renal cell carcinoma: a preliminary report | BMC Cancer | 2010 | 91 |
| 37 | Pumpless microfluidic system driven by hydrostatic pressure induces and maintains mouse spermatogenesis in vitro | Scientific Reports | 2017 | 90 |
| 38 | Production of Functional Spermatids from Mouse Germline Stem Cells in Ectopically Reconstituted Seminiferous Tubules1 | Biology of Reproduction | 2007 | 89 |
| 39 | Identification of miR-30d as a novel prognostic maker of prostate cancer | Oncotarget | 2012 | 88 |
| 40 | The Niche for Spermatogonial Stem Cells in the Mammalian Testis | International Journal of Hematology | 2005 | 86 |
| 41 | Genetic, epidemiologic and clinicopathologic studies of Japanese Asian patients with Birt–Hogg–Dubé syndrome | Clinical Genetics | 2016 | 85 |
| 42 | PTENMMAC1TEP1 mutations in human primary renal‐cell carcinomas and renal carcinoma cell lines | International Journal of Cancer | 2001 | 84 |
| 43 | In Vitro Murine Spermatogenesis in an Organ Culture System1 | Biology of Reproduction | 2010 | 84 |
| 44 | ELK1 is up-regulated by androgen in bladder cancer cells and promotes tumor progression | Oncotarget | 2015 | 84 |
| 45 | Cyclin D2, but not cyclin D1, overexpression closely correlates with gastric cancer progression and prognosis | Journal of Pathology | 1999 | 83 |
| 46 | Laxity of the Vaginal Introitus After Childbirth: Nonsurgical Outpatient Procedure for Vaginal Tissue Restoration and Improved Sexual Satisfaction Using Low-Energy Radiofrequency Thermal Therapy | Journal of Women's Health | 2013 | 83 |
| 47 | Impact of genetic polymorphisms of 17-hydroxylase cytochrome P-450(CYP17) and steroid 5?-reductase type II(SRD5A2) genes on prostate-cancer risk among the Japanese population | International Journal of Cancer | 2001 | 82 |
| 48 | The Most Reliable Preoperative Assessment of Renal Stone Burden as a Predictor of Stone-free Status After Flexible Ureteroscopy With Holmium Laser Lithotripsy: A Single-center Experience | Urology | 2012 | 80 |
| 49 | The potential of FDG-PET/CT for detecting prostate cancer in patients with an elevated serum PSA level | Annals of Nuclear Medicine | 2011 | 75 |
| 50 | Recurrent neomorphic mutations of MTOR in central nervous system and testicular germ cell tumors may be targeted for therapy | Acta Neuropathologica | 2016 | 75 |
