| # | Title | Journal | Year | Citations |
|---|
|
| 1 | Chronic catheterization of the spinal subarachnoid space | Physiology and Behavior | 1976 | 2,168 |
| 2 | The Stability of Cyclodextrin Complexes in Solution | Chemical Reviews | 1997 | 2,034 |
| 3 | Revision and Update of the Consensus Definitions of Invasive Fungal Disease From the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium | Clinical Infectious Diseases | 2020 | 1,620 |
| 4 | Program DYNAFIT for the Analysis of Enzyme Kinetic Data: Application to HIV Proteinase | Analytical Biochemistry | 1996 | 1,507 |
| 5 | Zebrafish as a Model Vertebrate for Investigating Chemical Toxicity | Toxicological Sciences | 2005 | 1,131 |
| 6 | Amphiphilic block copolymers for drug delivery | Journal of Pharmaceutical Sciences | 2003 | 958 |
| 7 | Intranasal delivery of biologics to the central nervous system | Advanced Drug Delivery Reviews | 2012 | 886 |
| 8 | Molecular mobility of amorphous pharmaceutical solids below their glass transition temperatures | Pharmaceutical Research | 1995 | 801 |
| 9 | Development and cross-sectional validation of the Childhood Asthma Control Test | Journal of Allergy and Clinical Immunology | 2007 | 749 |
| 10 | Identification of the NF-E2-related Factor-2-dependent Genes Conferring Protection against Oxidative Stress in Primary Cortical Astrocytes Using Oligonucleotide Microarray Analysis | Journal of Biological Chemistry | 2003 | 705 |
| 11 | Mass Spectrometry Imaging: A Review of Emerging Advancements and Future Insights | Analytical Chemistry | 2018 | 683 |
| 12 | Organic Glasses with Exceptional Thermodynamic and Kinetic Stability | Science | 2007 | 669 |
| 13 | Patient preferences for shared decisions: A systematic review | Patient Education and Counseling | 2012 | 658 |
| 14 | General Aspects and Optimization of Enantioselective Biocatalysis in Organic Solvents: The Use of Lipases[New Synthetic Methods(76)] | Angewandte Chemie International Edition in English | 1989 | 650 |
| 15 | Narcotic analgetics: CNS sites and mechanisms of action as revealed by intracerebral injection techniques | Pain | 1977 | 626 |
| 16 | The relationship between the glass transition temperature and the water content of amorphous pharmaceutical solids | Pharmaceutical Research | 1994 | 625 |
| 17 | Modulation of Polyketide Synthase Activity by Accessory Proteins During Lovastatin Biosynthesis | Science | 1999 | 613 |
| 18 | Developmental and Reproductive Toxicity of Dioxins and Related Compounds: Cross-Species Comparisons | Critical Reviews in Toxicology | 1993 | 590 |
| 19 | Determination of kinetic constants for peptidyl prolyl cis-trans isomerases by an improved spectrophotometric assay | Biochemistry | 1991 | 530 |
| 20 | Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 529 |
| 21 | Polymeric Micelles for Drug Delivery | Current Pharmaceutical Design | 2006 | 523 |
| 22 | The brief medication questionnaire: A tool for screening patient adherence and barriers to adherence | Patient Education and Counseling | 1999 | 518 |
| 23 | Nuclear Factor E2-Related Factor 2-Dependent Antioxidant Response Element Activation bytert-Butylhydroquinone and Sulforaphane Occurring Preferentially in Astrocytes Conditions Neurons against Oxidative Insult | Journal of Neuroscience | 2004 | 511 |
| 24 | An Important Role of Nrf2-ARE Pathway in the Cellular Defense Mechanism | BMB Reports | 2004 | 509 |
| 25 | Nrf2, a multi‐organ protector? | FASEB Journal | 2005 | 475 |
| 26 | Feeling bad on Facebook: depression disclosures by college students on a social networking site | Depression and Anxiety | 2011 | 461 |
| 27 | The role of brain barriers in fluid movement in the CNS: is there a ‘glymphatic’ system? | Acta Neuropathologica | 2018 | 456 |
| 28 | Bioadhesive‐Based Dosage Forms: The Next Generation | Journal of Pharmaceutical Sciences | 2000 | 441 |
| 29 | Polymeric Micelles for Delivery of Poorly Water-Soluble Compounds | Critical Reviews in Therapeutic Drug Carrier Systems | 2003 | 432 |
| 30 | Drug Delivery via the Mucous Membranes of the Oral Cavity | Journal of Pharmaceutical Sciences | 1992 | 418 |
| 31 | Crystallization of Indomethacin from the Amorphous State below and above Its Glass Transition Temperature | Journal of Pharmaceutical Sciences | 1994 | 413 |
| 32 | Factors influencing the efficiency of cationic liposome-mediated intravenous gene delivery | Nature Biotechnology | 1997 | 412 |
| 33 | Physical properties of solid molecular dispersions of indomethacin with poly(vinylpyrrolidone) and poly(vinylpyrrolidone-co-vinyl-acetate) in relation to indomethacin crystallization | Pharmaceutical Research | 1999 | 383 |
| 34 | Classifying Asthma Severity in Children | American Journal of Respiratory and Critical Care Medicine | 2004 | 383 |
| 35 | Voriconazole Therapeutic Drug Monitoring | Antimicrobial Agents and Chemotherapy | 2006 | 383 |
| 36 | Global economic burden of schizophrenia: a systematic review | Neuropsychiatric Disease and Treatment | 2016 | 371 |
| 37 | Curcumin for chemoprevention of colon cancer | Cancer Letters | 2007 | 368 |
| 38 | In utero and lactational exposure of male rats to 2,3,7,8-tetrachlorodibenzo-p-dioxin | Toxicology and Applied Pharmacology | 1992 | 359 |
| 39 | Introduction to nanocoatings produced by layer-by-layer (LbL) self-assembly | Advanced Drug Delivery Reviews | 2011 | 350 |
| 40 | Vitamin A in Reproduction and Development | Nutrients | 2011 | 334 |
| 41 | Enantioselective Bromolactonization of Conjugated (Z)-Enynes | Journal of the American Chemical Society | 2010 | 327 |
| 42 | Review of the Refeeding Syndrome | Nutrition in Clinical Practice | 2005 | 325 |
| 43 | A Transposon-Based Genetic Screen in Mice Identifies Genes Altered in Colorectal Cancer | Science | 2009 | 323 |
| 44 | In Vivo Tumor Targeting and Image-Guided Drug Delivery with Antibody-Conjugated, Radiolabeled Mesoporous Silica Nanoparticles | ACS Nano | 2013 | 320 |
| 45 | Allenamides: A Powerful and Versatile Building Block in Organic Synthesis | Chemical Reviews | 2013 | 320 |
| 46 | Polymorphism in Molecular Solids: An Extraordinary System of Red, Orange, and Yellow Crystals | Accounts of Chemical Research | 2010 | 319 |
| 47 | In utero and lactational exposure of male rats to 2,3,7,8-tetrachlorodibenzo-p-dioxin | Toxicology and Applied Pharmacology | 1992 | 315 |
| 48 | A Phase I, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose, Multiple Dose, and Food Effect Trial of the Safety, Tolerability and Pharmacokinetics of Highly Purified Cannabidiol in Healthy Subjects | CNS Drugs | 2018 | 313 |
| 49 | Assessing the performance of amorphous solid dispersions | Journal of Pharmaceutical Sciences | 2012 | 309 |
| 50 | Mechanisms of mucoadhesion of poly(acrylic acid) hydrogels | Pharmaceutical Research | 1987 | 307 |
