# | Title | Journal | Year | Citations |
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1 | CD4+CD25+ Immunoregulatory T Cells Suppress Polyclonal T Cell Activation In Vitro by Inhibiting Interleukin 2 Production | Journal of Experimental Medicine | 1998 | 2,323 |
2 | CD4+CD25+ Immunoregulatory T Cells | Immunity | 2002 | 1,297 |
3 | Stromal Cell Networks Regulate Lymphocyte Entry, Migration, and Territoriality in Lymph Nodes | Immunity | 2006 | 869 |
4 | A2A adenosine receptor protects tumors from antitumor T cells | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 837 |
5 | In Vivo Microbial Stimulation Induces Rapid CD40 Ligand–independent Production of Interleukin 12 by Dendritic Cells and their Redistribution to T Cell Areas | Journal of Experimental Medicine | 1997 | 836 |
6 | Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cell–dendritic cell interaction | Nature | 2006 | 752 |
7 | Dynamic Imaging of T Cell-Dendritic Cell Interactions in Lymph Nodes | Science | 2002 | 678 |
8 | Autophagic programmed cell death by selective catalase degradation | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 619 |
9 | T-cell development and the CD4–CD8 lineage decision | Nature Reviews Immunology | 2002 | 611 |
10 | Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency | Nature Immunology | 2014 | 575 |
11 | SAP-controlled T–B cell interactions underlie germinal centre formation | Nature | 2008 | 548 |
12 | The Adaptor MAVS Promotes NLRP3 Mitochondrial Localization and Inflammasome Activation | Cell | 2013 | 536 |
13 | Induction of CD8+ cytotoxic T cells by immunization with purified HIV-1 envelope protein in ISCOMs | Nature | 1990 | 505 |
14 | Control of T-cell activation by CD4+ CD25+ suppressor T cells | Immunological Reviews | 2001 | 499 |
15 | Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis | Nature | 2009 | 486 |
16 | Cutting Edge: IL-2 Is Essential for TGF-β-Mediated Induction of Foxp3+ T Regulatory Cells | Journal of Immunology | 2007 | 449 |
17 | Stromal cell contributions to the homeostasis and functionality of the immune system | Nature Reviews Immunology | 2009 | 444 |
18 | Engagement of Glucocorticoid-Induced TNFR Family-Related Receptor on Effector T Cells by its Ligand Mediates Resistance to Suppression by CD4+CD25+ T Cells | Journal of Immunology | 2004 | 443 |
19 | Role of A2a Extracellular Adenosine Receptor-Mediated Signaling in Adenosine-Mediated Inhibition of T-Cell Activation and Expansion | Blood | 1997 | 434 |
20 | TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways | Nature Immunology | 2003 | 426 |
21 | An Interleukin (IL)-10/IL-12 Immunoregulatory Circuit Controls Susceptibility to Autoimmune Disease | Journal of Experimental Medicine | 1998 | 425 |
22 | Modeling T Cell Antigen Discrimination Based on Feedback Control of Digital ERK Responses | PLoS Biology | 2005 | 420 |
23 | THE DYNAMICS OF T CELL RECEPTOR SIGNALING: Complex Orchestration and the Key Roles of Tempo and Cooperation | Annual Review of Immunology | 1999 | 410 |
24 | MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding | Nature | 1991 | 392 |
25 | Primary Vitreoretinal Lymphoma: A Report from an International Primary Central Nervous System Lymphoma Collaborative Group Symposium | Oncologist | 2011 | 386 |
26 | Receptor-Mediated Uptake of Antigen/Heat Shock Protein Complexes Results in Major Histocompatibility Complex Class I Antigen Presentation via Two Distinct Processing Pathways | Journal of Experimental Medicine | 2000 | 372 |
27 | Accelerated Telomere Erosion Is Associated with a Declining Immune Function of Caregivers of Alzheimer’s Disease Patients | Journal of Immunology | 2007 | 368 |
28 | Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes | Nature | 2002 | 365 |
29 | MHC class II interaction with CD4 mediated by a region analogous to the MHC class I binding site for CD8 | Nature | 1992 | 358 |
30 | Intraocular Lymphoma | Ophthalmology | 1993 | 343 |
31 | COOPERATION BETWEEN CD4+AND CD8+T CELLS: When, Where, and How | Annual Review of Immunology | 2006 | 332 |
32 | Macrophage and T Cell Dynamics during the Development and Disintegration of Mycobacterial Granulomas | Immunity | 2008 | 324 |
33 | Cutting Edge: Depletion of CD4+CD25+ Regulatory T Cells Is Necessary, But Not Sufficient, for Induction of Organ-Specific Autoimmune Disease | Journal of Immunology | 2002 | 310 |
34 | Variability and Robustness in T Cell Activation from Regulated Heterogeneity in Protein Levels | Science | 2008 | 306 |
35 | Noncanonical Autophagy Promotes the Visual Cycle | Cell | 2013 | 303 |
36 | Dynamic imaging of the immune system: progress, pitfalls and promise | Nature Reviews Immunology | 2006 | 284 |
37 | Transforming growth factor β: a matter of life and death | Journal of Leukocyte Biology | 1994 | 283 |
38 | A role for peptide in determining MHC class II structure | Nature | 1991 | 276 |
39 | CARRIER FUNCTION IN ANTI-HAPTEN IMMUNE RESPONSES | Journal of Experimental Medicine | 1970 | 270 |
40 | Natural killer cell behavior in lymph nodes revealed by static and real-time imaging | Journal of Experimental Medicine | 2006 | 266 |
41 | IL-4-induced immune deviation as antigen-specific therapy for inflammatory autoimmune disease | Trends in Immunology | 1996 | 257 |
42 | The GITR–GITRL interaction: co-stimulation or contrasuppression of regulatory activity? | Nature Reviews Immunology | 2006 | 252 |
43 | Heterozygous splice mutation in PIK3R1 causes human immunodeficiency with lymphoproliferation due to dominant activation of PI3K | Journal of Experimental Medicine | 2014 | 249 |
44 | Crystal structure of a lectin-like natural killer cell receptor bound to its MHC class I ligand | Nature | 1999 | 247 |
45 | GENETICS OF A NEW IgVH (T15 IDIOTYPE) MARKER IN THE MOUSE REGULATING NATURAL ANTIBODY TO PHOSPHORYLCHOLINE | Journal of Experimental Medicine | 1974 | 245 |
46 | ERM proteins regulate cytoskeleton relaxation promoting T cell–APC conjugation | Nature Immunology | 2004 | 245 |
47 | IL-2 Controls the Stability of Foxp3 Expression in TGF-β–Induced Foxp3+ T Cells In Vivo | Journal of Immunology | 2011 | 233 |
48 | Intravital Imaging Reveals Limited Antigen Presentation and T Cell Effector Function in Mycobacterial Granulomas | Immunity | 2011 | 226 |
49 | Expression of human β–hexosaminidase α–subunit gene (the gene defect of Tay–Sachs disease) in mouse brains upon engraftment of transduced progenitor cells | Nature Medicine | 1996 | 223 |
50 | T Helper Cell Differentiation, Heterogeneity, and Plasticity | Cold Spring Harbor Perspectives in Biology | 2018 | 222 |