# | Title | Journal | Year | Citations |
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1 | Dopamine, learning and motivation | Nature Reviews Neuroscience | 2004 | 2,955 |
2 | Incubation of cocaine craving after withdrawal | Nature | 2001 | 930 |
3 | Brain Reward Circuitry | Neuron | 2002 | 831 |
4 | Neurobiology of Relapse to Heroin and Cocaine Seeking: A Review | Pharmacological Reviews | 2002 | 774 |
5 | Dopamine Uptake through the Norepinephrine Transporter in Brain Regions with Low Levels of the Dopamine Transporter: Evidence from Knock-Out Mouse Lines | Journal of Neuroscience | 2002 | 557 |
6 | Dopamine and reward: The anhedonia hypothesis 30 years on | Neurotoxicity Research | 2008 | 496 |
7 | Central amygdala ERK signaling pathway is critical to incubation of cocaine craving | Nature Neuroscience | 2005 | 412 |
8 | Roles for nigrostriatal—not just mesocorticolimbic—dopamine in reward and addiction | Trends in Neurosciences | 2009 | 393 |
9 | Synergistic interaction between adenosine A2A and glutamate mGlu5 receptors: Implications for striatal neuronal function | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 345 |
10 | Cocaine Experience Establishes Control of Midbrain Glutamate and Dopamine by Corticotropin-Releasing Factor: A Role in Stress-Induced Relapse to Drug Seeking | Journal of Neuroscience | 2005 | 342 |
11 | Adenosine A2A receptors and basal ganglia physiology | Progress in Neurobiology | 2007 | 336 |
12 | Detection of heteromerization of more than two proteins by sequential BRET-FRET | Nature Methods | 2008 | 269 |
13 | A Single Infusion of Brain-Derived Neurotrophic Factor into the Ventral Tegmental Area Induces Long-Lasting Potentiation of Cocaine Seeking after Withdrawal | Journal of Neuroscience | 2004 | 263 |
14 | Ventral medial prefrontal cortex neuronal ensembles mediate context-induced relapse to heroin | Nature Neuroscience | 2011 | 258 |
15 | Maturation of silent synapses in amygdala-accumbens projection contributes to incubation of cocaine craving | Nature Neuroscience | 2013 | 256 |
16 | Forebrain substrates of reward and motivation | Journal of Comparative Neurology | 2005 | 250 |
17 | Metabotropic glutamate type 5, dopamine D2 and adenosine A2a receptors form higher‐order oligomers in living cells | Journal of Neurochemistry | 2009 | 249 |
18 | Targeted disruption of cocaine-activated nucleus accumbens neurons prevents context-specific sensitization | Nature Neuroscience | 2009 | 230 |
19 | A Role of Ventral Tegmental Area Glutamate in Contextual Cue-Induced Relapse to Heroin Seeking | Journal of Neuroscience | 2004 | 229 |
20 | Neuroactive steroids: potential therapeutic use in neurological and psychiatric disorders | Trends in Pharmacological Sciences | 1999 | 192 |
21 | Stress-induced relapse to cocaine seeking: roles for the CRF2 receptor and CRF-binding protein in the ventral tegmental area of the rat | Psychopharmacology | 2007 | 191 |
22 | Systemic and Central Amygdala Injections of the mGluR2/3 Agonist LY379268 Attenuate the Expression of Incubation of Cocaine Craving | Biological Psychiatry | 2007 | 190 |
23 | Deletion of the M5 muscarinic acetylcholine receptor attenuates morphine reinforcement and withdrawal but not morphine analgesia | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 180 |
24 | Dopamine D2 and Adenosine A2A Receptors Regulate NMDA-Mediated Excitation in Accumbens Neurons Through A2A–D2 Receptor Heteromerization | Neuropsychopharmacology | 2009 | 174 |
25 | Involvement of the Olfactory Tubercle in Cocaine Reward: Intracranial Self-Administration Studies | Journal of Neuroscience | 2003 | 172 |
26 | Basal ganglia circuit loops, dopamine and motivation: A review and enquiry | Behavioural Brain Research | 2015 | 165 |
27 | Primary Reinforcing Effects of Nicotine Are Triggered from Multiple Regions Both Inside and Outside the Ventral Tegmental Area | Journal of Neuroscience | 2006 | 163 |
28 | Motivational Effects of Cannabinoids and Opioids on Food Reinforcement Depend on Simultaneous Activation of Cannabinoid and Opioid Systems | Neuropsychopharmacology | 2005 | 158 |
29 | κ-Opioid Receptor Activation Modifies Dopamine Uptake in the Nucleus Accumbens and Opposes the Effects of Cocaine | Journal of Neuroscience | 2000 | 154 |
30 | Circuit and Synaptic Plasticity Mechanisms of Drug Relapse | Journal of Neuroscience | 2017 | 143 |
31 | Functional relevance of neurotransmitter receptor heteromers in the central nervous system | Trends in Neurosciences | 2007 | 136 |
32 | The role of neuroadaptations in relapse to drug seeking | Nature Neuroscience | 2005 | 132 |
33 | Reinstatement of Cocaine Seeking by Hypocretin (Orexin) in the Ventral Tegmental Area: Independence from the Local Corticotropin-Releasing Factor Network | Biological Psychiatry | 2009 | 125 |
34 | Cocaine-induced CREB phosphorylation in nucleus accumbens of cocaine-sensitized rats is enabled by enhanced activation of extracellular signal-related kinase, but not protein kinase A | Journal of Neurochemistry | 2005 | 123 |
35 | Mapping of chemical trigger zones for reward | Neuropharmacology | 2004 | 119 |
36 | Role of Orbitofrontal Cortex Neuronal Ensembles in the Expression of Incubation of Heroin Craving | Journal of Neuroscience | 2012 | 116 |
37 | Neurotransmitter receptor heteromers and their integrative role in ‘local modules’: The striatal spine module | Brain Research Reviews | 2007 | 112 |
38 | Ventral striatal anatomy of locomotor activity induced by cocaine, D-amphetamine, dopamine and D1/D2 agonists | Neuroscience | 2002 | 111 |
39 | The Functional Divide for Primary Reinforcement of D-Amphetamine Lies between the Medial and Lateral Ventral Striatum: Is the Division of the Accumbens Core, Shell, and Olfactory Tubercle Valid? | Journal of Neuroscience | 2005 | 110 |
40 | Long-Lasting Incubation of Conditioned Fear in Rats | Biological Psychiatry | 2009 | 108 |
41 | Adenosine receptor-mediated modulation of dopamine release in the nucleus accumbens depends on glutamate neurotransmission and N-methyl-d-aspartate receptor stimulation | Journal of Neurochemistry | 2004 | 107 |
42 | Cocaine-induced brain activation detected by dynamic manganese-enhanced magnetic resonance imaging (MEMRI) | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 107 |
43 | Behavioral, biological, and chemical perspectives on targeting CRF1 receptor antagonists to treat alcoholism | Drug and Alcohol Dependence | 2013 | 100 |
44 | Distinct Fos-Expressing Neuronal Ensembles in the Ventromedial Prefrontal Cortex Mediate Food Reward and Extinction Memories | Journal of Neuroscience | 2016 | 99 |
45 | A Role for Conditioned Ventral Tegmental Glutamate Release in Cocaine Seeking | Journal of Neuroscience | 2007 | 98 |
46 | Coordinated Interaction between Hippocampal Sharp-Wave Ripples and Anterior Cingulate Unit Activity | Journal of Neuroscience | 2016 | 97 |
47 | Brain temperature fluctuations during physiological and pathological conditions | European Journal of Applied Physiology | 2007 | 93 |
48 | Cannabinoid Agonists but not Inhibitors of Endogenous Cannabinoid Transport or Metabolism Enhance the Reinforcing Efficacy of Heroin in Rats | Neuropsychopharmacology | 2005 | 92 |
49 | Functional Implications of Glutamatergic Projections to the Ventral Tegmental Area | Reviews in the Neurosciences | 2008 | 89 |
50 | Heterodimeric adenosine receptors: a device to regulate neurotransmitter release | Cellular and Molecular Life Sciences | 2006 | 88 |