| # | Title | Journal | Year | Citations |
|---|
| 1 | The Hypothalamic–Pituitary–Adrenal Axis and Immune-Mediated Inflammation | New England Journal of Medicine | 1995 | 2,378 |
| 2 | A Muscle-Specific Insulin Receptor Knockout Exhibits Features of the Metabolic Syndrome of NIDDM without Altering Glucose Tolerance | Molecular Cell | 1998 | 1,071 |
| 3 | Care of Girls and Women with Turner Syndrome: A Guideline of the Turner Syndrome Study Group | Journal of Clinical Endocrinology and Metabolism | 2007 | 890 |
| 4 | The concepts of stress and stress system disorders. Overview of physical and behavioral homeostasis | JAMA - Journal of the American Medical Association | 1992 | 822 |
| 5 | A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty | Nature | 1993 | 743 |
| 6 | Stress Hormones, Th1/Th2 patterns, Pro/Anti-inflammatory Cytokines and Susceptibility to Disease | Trends in Endocrinology and Metabolism | 1999 | 679 |
| 7 | Clinical and Molecular Features of the Carney Complex: Diagnostic Criteria and Recommendations for Patient Evaluation | Journal of Clinical Endocrinology and Metabolism | 2001 | 674 |
| 8 | Human leptin levels are pulsatile and inversely related to pituitary–ardenal function | Nature Medicine | 1997 | 637 |
| 9 | Androgens stimulate early stages of follicular growth in the primate ovary. | Journal of Clinical Investigation | 1998 | 614 |
| 10 | Glucocorticoid receptor beta, a potential endogenous inhibitor of glucocorticoid action in humans. | Journal of Clinical Investigation | 1995 | 571 |
| 11 | Androgen and Follicle-Stimulating Hormone Interactions in Primate Ovarian Follicle Development | Journal of Clinical Endocrinology and Metabolism | 1999 | 537 |
| 12 | Development of a Novel Polygenic Model of NIDDM in Mice Heterozygous for IR and IRS-1 Null Alleles | Cell | 1997 | 517 |
| 13 | Mater, a maternal effect gene required for early embryonic development in mice | Nature Genetics | 2000 | 487 |
| 14 | Autocrine or paracrine inflammatory actions of corticotropin-releasing hormone in vivo | Science | 1991 | 480 |
| 15 | Recombinant interleukin-6 activates the hypothalamic-pituitary-adrenal axis in humans. | Journal of Clinical Endocrinology and Metabolism | 1993 | 457 |
| 16 | Clinical and molecular genetics of patients with the Carney–Stratakis syndrome and germline mutations of the genes coding for the succinate dehydrogenase subunits SDHB, SDHC, and SDHD | European Journal of Human Genetics | 2008 | 446 |
| 17 | Hyperphagia, Severe Obesity, Impaired Cognitive Function, and Hyperactivity Associated With Functional Loss of One Copy of the Brain-Derived Neurotrophic Factor (BDNF) Gene | Diabetes | 2006 | 421 |
| 18 | Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2 | Journal of Clinical Investigation | 2000 | 419 |
| 19 | Insulin Stimulates Phosphorylation of the Forkhead Transcription Factor FKHR on Serine 253 through a Wortmannin-sensitive Pathway | Journal of Biological Chemistry | 1999 | 417 |
| 20 | Cushing's Syndrome in Children and Adolescents -- Presentation, Diagnosis, and Therapy | New England Journal of Medicine | 1994 | 411 |
| 21 | Evidence of direct estrogenic regulation of human corticotropin-releasing hormone gene expression. Potential implications for the sexual dimophism of the stress response and immune/inflammatory reaction. | Journal of Clinical Investigation | 1993 | 397 |
| 22 | Orlistat, a New Lipase Inhibitor for the Management of Obesity | Pharmacotherapy | 2000 | 373 |
| 23 | The FMR1 premutation and reproduction | Fertility and Sterility | 2007 | 360 |
| 24 | Estrogen levels in childhood determined by an ultrasensitive recombinant cell bioassay. | Journal of Clinical Investigation | 1994 | 331 |
| 25 | Point mutation causing a single amino acid substitution in the hormone binding domain of the glucocorticoid receptor in familial glucocorticoid resistance. | Journal of Clinical Investigation | 1991 | 331 |
| 26 | Aortic Dilatation and Dissection in Turner Syndrome | Circulation | 2007 | 328 |
| 27 | Insulin-like growth factors cross the blood-brain barrier. | Endocrinology | 1994 | 327 |
| 28 | A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia | Nature Genetics | 2006 | 316 |
| 29 | Cellular Pattern of Insulin-Like Growth Factor-I (IGF-I) and Type I IGF Receptor Gene Expression in Early Organogenesis: Comparison with IGF-II Gene Expression | Molecular Endocrinology | 1990 | 312 |
| 30 | Androgen Receptor Gene Expression in the Primate Ovary: Cellular Localization, Regulation, and Functional Correlations | Journal of Clinical Endocrinology and Metabolism | 1998 | 308 |
| 31 | Familial paraganglioma and gastric stromal sarcoma: A new syndrome distinct from the Carney triad | American Journal of Medical Genetics Part A | 2002 | 307 |
| 32 | Transient IGF-I gene expression during the maturation of functionally related central projection neurons | Journal of Neuroscience | 1991 | 288 |
| 33 | Dose-Dependent Effects of Recombinant Human Interleukin-6 on Glucose Regulation | Journal of Clinical Endocrinology and Metabolism | 1997 | 286 |
| 34 | Spontaneous Growth Hormone Secretion Increases during Puberty in Normal Girls and Boys* | Journal of Clinical Endocrinology and Metabolism | 1991 | 282 |
| 35 | Endocrine Regulation of the Growth Plate | Hormone Research in Paediatrics | 2005 | 282 |
| 36 | Adrenocorticotropin (ACTH)- and Non-ACTH-Mediated Regulation of the Adrenal Cortex: Neural and Immune Inputs | Journal of Clinical Endocrinology and Metabolism | 1999 | 281 |
| 37 | The effect of anorexia nervosa and refeeding on growth hormone-binding protein, the insulin-like growth factors (IGFs), and the IGF-binding proteins. | Journal of Clinical Endocrinology and Metabolism | 1992 | 275 |
| 38 | Effects of estrogen on growth plate senescence and epiphyseal fusion | Proceedings of the National Academy of Sciences of the United States of America | 2001 | 268 |
| 39 | Phosphatidylinositol 3-Kinase-dependent Membrane Association of the Bruton's Tyrosine Kinase Pleckstrin Homology Domain Visualized in Single Living Cells | Journal of Biological Chemistry | 1999 | 259 |
| 40 | The Endocrinology of Melancholic and Atypical Depression: Relation to Neurocircuitry and Somatic Consequences | Proceedings of the Association of American Physicians | 1999 | 251 |
| 41 | The Role of the Resting Zone in Growth Plate Chondrogenesis | Endocrinology | 2002 | 240 |
| 42 | Gonadotropin Secretory Dynamics During Puberty in Normal Girls and Boys | Journal of Clinical Endocrinology and Metabolism | 1990 | 233 |
| 43 | Dose Effects of Recombinant Human lnterleukin-6 on Pituitary Hormone Secretion and Energy Expenditure | Neuroendocrinology | 1997 | 226 |
| 44 | Interactions between Tumor Necrosis Factor-α, Hypothalamic Corticotropin-Releasing Hormone, and Adrenocorticotropin Secretion in the Rat* | Endocrinology | 1990 | 222 |
| 45 | Ligand-Activation of the Adenosine A2a Receptors Inhibits IL-12 Production by Human Monocytes | Journal of Immunology | 2000 | 221 |
| 46 | Igf1 promotes longitudinal bone growth by insulin‐like actions augmenting chondrocyte hypertrophy | FASEB Journal | 1999 | 220 |
| 47 | Indices of Insulin Action, Disposal, and Secretion Derived From Fasting Samples and Clamps in Normal Glucose-Tolerant Black and White Children | Diabetes Care | 2002 | 219 |
| 48 | The effects of estrogen priming and puberty on the growth hormone response to standardized treadmill exercise and arginine-insulin in normal girls and boys. | Journal of Clinical Endocrinology and Metabolism | 1994 | 208 |
| 49 | Hypothalamic-pituitary-adrenal axis activation and stimulation of systemic vasopressin secretion by recombinant interleukin-6 in humans: potential implications for the syndrome of inappropriate vasopressin secretion. | Journal of Clinical Endocrinology and Metabolism | 1994 | 207 |
| 50 | The role of estrogen in bone growth and maturation during childhood and adolescence | Journal of Steroid Biochemistry and Molecular Biology | 1997 | 207 |
