| # | Title | Journal | Year | Citations |
|---|
| 1 | New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk | Nature Genetics | 2010 | 1,982 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 3 | Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence | Nature Genetics | 2018 | 893 |
| 4 | European consensus conference on faecal microbiota transplantation in clinical practice | Gut | 2017 | 793 |
| 5 | Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European Atherosclerosis Society Consensus Panel | European Heart Journal | 2020 | 776 |
| 6 | Prenatal developmental origins of behavior and mental health: The influence of maternal stress in pregnancy | Neuroscience and Biobehavioral Reviews | 2020 | 681 |
| 7 | Gut microbiome and health: mechanistic insights | Gut | 2022 | 661 |
| 8 | Patterns of metastasis in colon and rectal cancer | Scientific Reports | 2016 | 652 |
| 9 | Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function | Nature Communications | 2018 | 484 |
| 10 | Predictors and subjective causes of loneliness in an aged population | Archives of Gerontology and Geriatrics | 2005 | 474 |
| 11 | A sensitive assay for dNTPs based on long synthetic oligonucleotides, EvaGreen dye and inhibitor-resistant high-fidelity DNA polymerase | Nucleic Acids Research | 2020 | 446 |
| 12 | Meta‐analysis of observational studies of serum 25‐hydroxyvitamin D levels and colorectal, breast and prostate cancer and colorectal adenoma | International Journal of Cancer | 2011 | 421 |
| 13 | The Potential of Gut Commensals in Reinforcing Intestinal Barrier Function and Alleviating Inflammation | Nutrients | 2018 | 380 |
| 14 | Overweight, obesity, and risk of cardiometabolic multimorbidity: pooled analysis of individual-level data for 120 813 adults from 16 cohort studies from the USA and Europe | Lancet Public Health, The | 2017 | 375 |
| 15 | Modelling aerosol transport and virus exposure with numerical simulations in relation to SARS-CoV-2 transmission by inhalation indoors | Safety Science | 2020 | 349 |
| 16 | Pili-like proteins of Akkermansia muciniphila modulate host immune responses and gut barrier function | PLoS ONE | 2017 | 340 |
| 17 | Association between socioeconomic status and the development of mental and physical health conditions in adulthood: a multi-cohort study | Lancet Public Health, The | 2020 | 332 |
| 18 | Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders | American Journal of Human Genetics | 2018 | 326 |
| 19 | Music-based interventions in neurological rehabilitation | Lancet Neurology, The | 2017 | 316 |
| 20 | Maternal gut and breast milk microbiota affect infant gut antibiotic resistome and mobile genetic elements | Nature Communications | 2018 | 313 |
| 21 | International consensus conference on stool banking for faecal microbiota transplantation in clinical practice | Gut | 2019 | 290 |
| 22 | Risk factors for endometrial cancer: An umbrella review of the literature | International Journal of Cancer | 2019 | 290 |
| 23 | PERSONALITY AND DEPRESSIVE SYMPTOMS: INDIVIDUAL PARTICIPANT META-ANALYSIS OF 10 COHORT STUDIES | Depression and Anxiety | 2015 | 288 |
| 24 | Taxonomy of the order Bunyavirales: update 2019 | Archives of Virology | 2019 | 285 |
| 25 | Oxidative stress in anxiety and comorbid disorders | Neuroscience Research | 2010 | 284 |
| 26 | Body mass index and risk of dementia: Analysis of individual‐level data from 1.3 million individuals | Alzheimer's and Dementia | 2018 | 284 |
| 27 | Metastatic spread in patients with gastric cancer | Oncotarget | 2016 | 272 |
| 28 | Seipin regulates ER–lipid droplet contacts and cargo delivery | EMBO Journal | 2016 | 258 |
| 29 | Contribution of risk factors to excess mortality in isolated and lonely individuals: an analysis of data from the UK Biobank cohort study | Lancet Public Health, The | 2017 | 256 |
| 30 | Systematic review of light exposure impact on human circadian rhythm | Chronobiology International | 2019 | 253 |
| 31 | Obesity and loss of disease-free years owing to major non-communicable diseases: a multicohort study | Lancet Public Health, The | 2018 | 241 |
| 32 | Childhood Adversities Are Associated with Shorter Telomere Length at Adult Age both in Individuals with an Anxiety Disorder and Controls | PLoS ONE | 2010 | 234 |
| 33 | The epidemiology of metastases in neuroendocrine tumors | International Journal of Cancer | 2016 | 233 |
| 34 | Effort–Reward Imbalance at Work and Incident Coronary Heart Disease | Epidemiology | 2017 | 224 |
| 35 | Systematic Review and Meta-Analysis of the Efficacy and Safety of Existing TNF Blocking Agents in Treatment of Rheumatoid Arthritis | PLoS ONE | 2012 | 221 |
| 36 | Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation | Nature Genetics | 2021 | 218 |
| 37 | Patient‐level meta‐analysis of the EDITION 1, 2 and 3 studies: glycaemic control and hypoglycaemia with new insulin glargine 300 U/ml versus glargine 100 U/ml in people with type 2 diabetes | Diabetes, Obesity and Metabolism | 2015 | 207 |
| 38 | Quantitative PCR provides a simple and accessible method for quantitative microbiota profiling | PLoS ONE | 2020 | 207 |
| 39 | Near-Infrared Fluorescent Proteins, Biosensors, and Optogenetic Tools Engineered from Phytochromes | Chemical Reviews | 2017 | 204 |
| 40 | Social isolation and loneliness as risk factors for myocardial infarction, stroke and mortality: UK Biobank cohort study of 479 054 men and women | Heart | 2018 | 194 |
| 41 | Pancreatic cancer therapy with combined mesothelin-redirected chimeric antigen receptor T cells and cytokine-armed oncolytic adenoviruses | JCI Insight | 2018 | 191 |
| 42 | Maternal Fecal Microbiota Transplantation in Cesarean-Born Infants Rapidly Restores Normal Gut Microbial Development: A Proof-of-Concept Study | Cell | 2020 | 188 |
| 43 | Associations Between Maternal Antenatal Corticosteroid Treatment and Mental and Behavioral Disorders in Children | JAMA - Journal of the American Medical Association | 2020 | 187 |
| 44 | The in vivo Expression of the Collagenolytic Matrix Metalloproteinases (MMP-2, -8, -13, and -14) and Matrilysin (MMP-7) in Adult and Localized Juvenile Periodontitis | Journal of Dental Research | 2000 | 186 |
| 45 | Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation | Nature Communications | 2018 | 181 |
| 46 | Personality and alcohol consumption: Pooled analysis of 72,949 adults from eight cohort studies | Drug and Alcohol Dependence | 2015 | 173 |
| 47 | Heart failure and diabetes: metabolic alterations and therapeutic interventions: a state-of-the-art review from the Translational Research Committee of the Heart Failure Association–European Society of Cardiology | European Heart Journal | 2018 | 171 |
| 48 | Physical inactivity, cardiometabolic disease, and risk of dementia: an individual-participant meta-analysis | BMJ: British Medical Journal | 2019 | 168 |
| 49 | Protein Coating of DNA Nanostructures for Enhanced Stability and Immunocompatibility | Advanced Healthcare Materials | 2017 | 166 |
| 50 | Fibroblast Growth Factor 21 Drives Dynamics of Local and Systemic Stress Responses in Mitochondrial Myopathy with mtDNA Deletions | Cell Metabolism | 2019 | 166 |
