| # | Title | Journal | Year | Citations |
|---|
| 1 | Prebiotic effects: metabolic and health benefits | British Journal of Nutrition | 2010 | 1,745 |
| 2 | Appropriate prescribing in elderly people: how well can it be measured and optimised? | Lancet, The | 2007 | 893 |
| 3 | Pharmacokinetics and dosage adjustment in patients with hepatic dysfunction | European Journal of Clinical Pharmacology | 2008 | 518 |
| 4 | The challenge of managing drug interactions in elderly people | Lancet, The | 2007 | 445 |
| 5 | Pharmacokinetics and dosage adjustment in patients with renal dysfunction | European Journal of Clinical Pharmacology | 2009 | 392 |
| 6 | Influence of formulation excipients and physical characteristics of inhalation dry powders on their aerosolization performance | Journal of Controlled Release | 2001 | 266 |
| 7 | Effect of a Collaborative Approach on the Quality of Prescribing for Geriatric Inpatients: A Randomized, Controlled Trial | Journal of the American Geriatrics Society | 2007 | 262 |
| 8 | Oligosaccharides: state of the art | Proceedings of the Nutrition Society | 2003 | 163 |
| 9 | Inulin and oligofructose modulate lipid metabolism in animals: review of biochemical events and future prospects | British Journal of Nutrition | 2002 | 157 |
| 10 | Hepatic microsomal metabolism of 1,3-butadiene | Xenobiotica | 1982 | 149 |
| 11 | Dietary Fructans, but Not Cellulose, Decrease Triglyceride Accumulation in the Liver of Obese Zucker fa/fa Rats | Journal of Nutrition | 2002 | 144 |
| 12 | Dietary Oligofructose Lessens Hepatic Steatosis, but Does Not Prevent Hypertriglyceridemia in Obese Zucker Rats | Journal of Nutrition | 2000 | 141 |
| 13 | Pulmonary delivery of growth hormone using dry powders and visualization of its local fate in rats | Journal of Controlled Release | 2004 | 129 |
| 14 | Comparative Clinical Pharmacokinetics of Tacrolimus in Paediatric and Adult Patients | Clinical Pharmacokinetics | 2001 | 124 |
| 15 | Synthesis and Anticonvulsant Activity of 2(3H)-Benzoxazolone and 2(3H)-Benzothiazolone Derivatives | Journal of Medicinal Chemistry | 1998 | 119 |
| 16 | In vivo efficacy and safety of skin electroporation | Advanced Drug Delivery Reviews | 1999 | 115 |
| 17 | Aerosolization properties, surface composition and physical state of spray-dried protein powders | Journal of Controlled Release | 2004 | 111 |
| 18 | Dietary supplementation with laminarin, a fermentable marine β (1–3) glucan, protects against hepatotoxicity induced by LPS in rat by modulating immune response in the hepatic tissue | International Immunopharmacology | 2007 | 94 |
| 19 | Alveolar macrophages are a primary barrier to pulmonary absorption of macromolecules | American Journal of Physiology - Lung Cellular and Molecular Physiology | 2004 | 91 |
| 20 | Pharmacokinetic Drug Interactions with Nonsteroidal Anti-Inflammatory Drugs | Clinical Pharmacokinetics | 1990 | 87 |
| 21 | Implementation of Ward-Based Clinical Pharmacy Services in Belgium—Description of the Impact on a Geriatric Unit | Annals of Pharmacotherapy | 2006 | 85 |
| 22 | Systemic delivery of parathyroid hormone (1-34) using inhalation dry powders in rats | Journal of Pharmaceutical Sciences | 2003 | 84 |
| 23 | Appropriateness of use of medicines in elderly inpatients: qualitative study | BMJ: British Medical Journal | 2005 | 81 |
| 24 | Improvement of the decision efficiency of the accuracy profile by means of a desirability function for analytical methods validation | Analytica Chimica Acta | 2007 | 76 |
| 25 | Impact of formulation and methods of pulmonary delivery on absorption of parathyroid hormone (1–34) from rat lungs | Journal of Pharmaceutical Sciences | 2004 | 75 |
| 26 | Extrahepatic glucuronidation of propofol in man: possible contribution of gut wall and kidney | European Journal of Clinical Pharmacology | 1996 | 73 |
| 27 | Blood microdialysis in pharmacokinetic and drug metabolism studies | Advanced Drug Delivery Reviews | 2000 | 73 |
| 28 | Comparison of the effects of short, high-voltage and long, medium-voltage pulses on skin electrical and transport properties | Journal of Controlled Release | 1999 | 68 |
| 29 | Inulin and oligofructose modulate lipid metabolism in animals: review of biochemical events and future prospects | British Journal of Nutrition | 2002 | 59 |
| 30 | Permeability of 13 different gloves to 13 cytotoxic agents under controlled dynamic conditions | American Journal of Health-System Pharmacy | 2006 | 56 |
| 31 | Comparison of particle sizing techniques in the case of inhalation dry powders | Journal of Pharmaceutical Sciences | 2001 | 55 |
| 32 | Effect on Components of the Intestinal Microflora and Plasma Neuropeptide Levels of Feeding Lactobacillus delbrueckii, Bifidobacterium lactis, and Inulin to Adult and Elderly Rats | Applied and Environmental Microbiology | 2006 | 55 |
| 33 | C-terminal FGF23 is a strong predictor of survival in systolic heart failure | Peptides | 2012 | 54 |
| 34 | Limited Sampling Models and Bayesian Estimation for Mycophenolic Acid Area under the Curve Prediction in Stable Renal Transplant Patients Co-Medicated with Ciclosporin or Sirolimus | Clinical Pharmacokinetics | 2009 | 52 |
| 35 | Conversion of a Highly Selective Sigma-1 Receptor–Ligand to Sigma-2 Receptor Preferring Ligands with Anticocaine Activity | Journal of Medicinal Chemistry | 2008 | 50 |
| 36 | Mutagenicity of acrylonitrile | Toxicology | 1978 | 48 |
| 37 | Intravenous microdialysis in the mouse and the rat: development and pharmacokinetic application of a new probe | Pharmaceutical Research | 1996 | 47 |
| 38 | Endocannabinoids and related N-acylethanolamines in the control of appetite and energy metabolism: emergence of new molecular players | Current Opinion in Clinical Nutrition and Metabolic Care | 2007 | 46 |
| 39 | Confocal imaging of rat lungs following intratracheal delivery of dry powders or solutions of fluorescent probes | Journal of Controlled Release | 2002 | 40 |
| 40 | N-(Benzyloxycarbonyl)glycine Esters and Amides as New Anticonvulsants | Journal of Medicinal Chemistry | 1998 | 39 |
| 41 | Prediction of paraquat exposure and toxicity in clinically ill poisoned patients: a model based approach | British Journal of Clinical Pharmacology | 2014 | 39 |
| 42 | From receptor internalization to nuclear translocation | Biochemical Pharmacology | 1994 | 37 |
| 43 | Sensitive assay for midazolam and its metabolite 1′-hydroxymidazolam in human plasma by capillary high-performance liquid chromatography | Biomedical Applications | 1998 | 36 |
| 44 | Comparative Anticonvulsant Activity and Neurotoxicity of 4-Amino-N-(2,6-Dimethylphenyl)Phthalimide and Prototype Antiepileptic Drugs in Mice and Rats | Epilepsia | 1995 | 30 |
| 45 | Simultaneous microdialysis in brain and blood of the mouse: extracellular and intracellular brain colchicine disposition | Brain Research | 1998 | 30 |
| 46 | Glucuronidation of diflunisal by rat liver microsomes | Biochemical Pharmacology | 1993 | 28 |
| 47 | Mutagenicity of urine from rats and mice treated with acrylonitrile | Toxicology | 1980 | 27 |
| 48 | Determination of oxide synthetase and hydratase activities by a new highly sensitive gas chromatographic method using styrene and styrene oxide as substrates | Biochimica Et Biophysica Acta - Biomembranes | 1978 | 26 |
| 49 | Local and Systemic Immune Responses to Intratracheal Instillation of Antigen and DNA Vaccines in Mice | Pharmaceutical Research | 2004 | 26 |
| 50 | Glucuronidation of R- and S-ketoprofen, acetaminophen, and diflunisal by liver microsomes of adjuvant-induced arthritic rats | Drug Metabolism and Disposition | 1999 | 26 |
