# | Title | Journal | Year | Citations |
---|
1 | THE UBIQUITIN SYSTEM | Annual Review of Biochemistry | 1998 | 7,702 |
2 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
3 | Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci | Nature Genetics | 2010 | 2,284 |
4 | The ubiquitin-proteasome proteolytic pathway | Cell | 1994 | 1,751 |
5 | The Ubiquitin System for Protein Degradation | Annual Review of Biochemistry | 1992 | 1,415 |
6 | Differentiation of Human Embryonic Stem Cells into Embryoid Bodies Comprising the Three Embryonic Germ Layers | Molecular Medicine | 2000 | 1,377 |
7 | A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure | Cell Systems | 2016 | 1,098 |
8 | The human tumor microbiome is composed of tumor type–specific intracellular bacteria | Science | 2020 | 1,077 |
9 | Modelling the long QT syndrome with induced pluripotent stem cells | Nature | 2011 | 957 |
10 | Global longitudinal strain: a novel index of left ventricular systolic function | Journal of the American Society of Echocardiography | 2004 | 650 |
11 | The ubiquitin system | Nature Medicine | 2000 | 625 |
12 | ImmPort, toward repurposing of open access immunological assay data for translational and clinical research | Scientific Data | 2018 | 529 |
13 | Early Management of Shock and Prophylaxis of Acute Renal Failure in Traumatic Rhabdomyolysis | New England Journal of Medicine | 1990 | 525 |
14 | Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers | Molecular Medicine | 2000 | 435 |
15 | Ultrashort sleep-waking schedule. III. ‘Gates’ and ‘Forbidden zones’ for sleep | Electroencephalography and Clinical Neurophysiology | 1986 | 433 |
16 | Cytoplasmic 5′-3′ exonuclease Xrn1p is also a genome-wide transcription factor in yeast | Frontiers in Genetics | 2014 | 427 |
17 | THE UBIQUITIN-PROTEASOME PATHWAY AND PATHOGENESIS OF HUMAN DISEASES | Annual Review of Medicine | 1999 | 426 |
18 | p38 Mitogen-activated Protein Kinase Pathway Promotes Skeletal Muscle Differentiation | Journal of Biological Chemistry | 1999 | 423 |
19 | Ubiquitin-mediated protein degradation. | Journal of Biological Chemistry | 1988 | 418 |
20 | Induced neuronal differentiation of human embryonic stem cells | Brain Research | 2001 | 410 |
21 | Engineering the Growth Factor Microenvironment with Fibronectin Domains to Promote Wound and Bone Tissue Healing | Science Translational Medicine | 2011 | 391 |
22 | Targeting mitochondrial oxidative phosphorylation eradicates therapy-resistant chronic myeloid leukemia stem cells | Nature Medicine | 2017 | 382 |
23 | The global distribution of tetrapods reveals a need for targeted reptile conservation | Nature Ecology and Evolution | 2017 | 378 |
24 | ATP-dependent incorporation of 20S protease into the 26S complex that degrades proteins conjugated to ubiquitin. | Proceedings of the National Academy of Sciences of the United States of America | 1989 | 374 |
25 | Mortality in Sleep Apnea Patients: A Multivariate Analysis of Risk Factors | Sleep | 1995 | 372 |
26 | A Maximum a Posteriori Probability Expectation Maximization Algorithm for Image Reconstruction in Emission Tomography | IEEE Transactions on Medical Imaging | 1987 | 366 |
27 | Development of a capsule endoscopy scoring index for small bowel mucosal inflammatory change | Alimentary Pharmacology and Therapeutics | 2008 | 361 |
28 | Establishment of human embryonic stem cell-transfected clones carrying a marker for undifferentiated cells | Current Biology | 2001 | 360 |
29 | Ubiquitin-mediated protein degradation | Journal of Biological Chemistry | 1988 | 357 |
30 | Evaluation of COVID-19 RT-qPCR Test in Multi sample Pools | Clinical Infectious Diseases | 2020 | 350 |
31 | Degradation of nuclear oncoproteins by the ubiquitin system in vitro. | Proceedings of the National Academy of Sciences of the United States of America | 1991 | 349 |
32 | Dynamics and Effective Topology Underlying Synchronization in Networks of Cortical Neurons | Journal of Neuroscience | 2006 | 348 |
33 | Sleep Disturbances in the Wake of Traumatic Events | New England Journal of Medicine | 2001 | 327 |
34 | A clinically meaningful metric of immune age derived from high-dimensional longitudinal monitoring | Nature Medicine | 2019 | 317 |
35 | Bowel preparation for colonoscopy: European Society of Gastrointestinal Endoscopy (ESGE) Guideline – Update 2019 | Endoscopy | 2019 | 309 |
36 | Induction of preovulatory luteinizing hormone surge and prevention of ovarian hyperstimulation syndrome by gonadotropin-releasing hormone agonist | Fertility and Sterility | 1991 | 300 |
37 | Social network architecture of human immune cells unveiled by quantitative proteomics | Nature Immunology | 2017 | 296 |
38 | The p38 MAPK signaling pathway: A major regulator of skeletal muscle development | Molecular and Cellular Endocrinology | 2006 | 290 |
39 | High-Resolution Electrophysiological Assessment of Human Embryonic Stem Cell-Derived Cardiomyocytes | Circulation Research | 2002 | 281 |
40 | All-cause mortality in males with sleep apnoea syndrome: declining mortality rates with age | European Respiratory Journal | 2005 | 276 |
41 | Controlled, Scalable Embryonic Stem Cell Differentiation Culture | Stem Cells | 2004 | 272 |
42 | Computational deconvolution: extracting cell type-specific information from heterogeneous samples | Current Opinion in Immunology | 2013 | 270 |
43 | UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma | Cell | 2019 | 270 |
44 | Selective Ablation of Human Embryonic Stem Cells Expressing a "Suicide" Gene | Stem Cells | 2003 | 267 |
45 | High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity | Nature Biotechnology | 2010 | 258 |
46 | Seven Versus 14 Days of Antibiotic Therapy for Uncomplicated Gram-negative Bacteremia: A Noninferiority Randomized Controlled Trial | Clinical Infectious Diseases | 2019 | 256 |
47 | Pulmonary Hypertension in Patients With End-Stage Renal Disease | Chest | 2003 | 254 |
48 | Lymphocytes, neuropeptides, and genes involved in alopecia areata | Journal of Clinical Investigation | 2007 | 243 |
49 | Pathologic alterations of cutaneous innervation and vasculature in affected limbs from patients with complex regional pain syndrome | Pain | 2006 | 242 |
50 | Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration | Cell Metabolism | 2019 | 236 |