# | Title | Journal | Year | Citations |
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|
1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,789 |
2 | Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease | Nature Genetics | 2013 | 3,872 |
3 | Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing | Nature Genetics | 2019 | 2,145 |
4 | CREB: A Stimulus-Induced Transcription Factor Activated by A Diverse Array of Extracellular Signals | Annual Review of Biochemistry | 1999 | 1,960 |
5 | The cholinergic hypothesis of Alzheimer's disease: a review of progress | Journal of Neurology, Neurosurgery and Psychiatry | 1999 | 1,754 |
6 | Mitochondria as sensors and regulators of calcium signalling | Nature Reviews Molecular Cell Biology | 2012 | 1,416 |
7 | InterPro in 2017—beyond protein family and domain annotations | Nucleic Acids Research | 2017 | 1,402 |
8 | Reactive astrocyte nomenclature, definitions, and future directions | Nature Neuroscience | 2021 | 1,292 |
9 | Derepression of BDNF Transcription Involves Calcium-Dependent Phosphorylation of MeCP2 | Science | 2003 | 1,148 |
10 | The Expression of Vesicular Glutamate Transporters Defines Two Classes of Excitatory Synapse | Neuron | 2001 | 1,142 |
11 | The Unfolded Protein Response and Cell Fate Control | Molecular Cell | 2018 | 1,072 |
12 | Generating stimuli for neuroscience using PsychoPy | Frontiers in Neuroinformatics | 2008 | 1,016 |
13 | Increased Neurogenesis in the Dentate Gyrus After Transient Global Ischemia in Gerbils | Journal of Neuroscience | 1998 | 1,009 |
14 | New insights into the genetic etiology of Alzheimer’s disease and related dementias | Nature Genetics | 2022 | 981 |
15 | Single App knock-in mouse models of Alzheimer's disease | Nature Neuroscience | 2014 | 938 |
16 | Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice | Nature Medicine | 2014 | 905 |
17 | Dimers of mitochondrial ATP synthase form the permeability transition pore | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 835 |
18 | Identification and characterization of the vesicular GABA transporter | Nature | 1997 | 828 |
19 | Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease | Nature Genetics | 2017 | 818 |
20 | Changes in sleep pattern, sense of time and digital media use during COVID‐19 lockdown in Italy | Journal of Sleep Research | 2020 | 804 |
21 | The Brain on Stress: Vulnerability and Plasticity of the Prefrontal Cortex over the Life Course | Neuron | 2013 | 782 |
22 | Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum | Development (Cambridge) | 1999 | 768 |
23 | Behavioural and neurochemical effects of post-weaning social isolation in rodents—Relevance to developmental neuropsychiatric disorders | Neuroscience and Biobehavioral Reviews | 2008 | 767 |
24 | Uptake of Glutamate into Synaptic Vesicles by an Inorganic Phosphate Transporter | Science | 2000 | 736 |
25 | Evidence for bulk flow of brain interstitial fluid: significance for physiology and pathology | Neurochemistry International | 2004 | 725 |
26 | Properties of the Permeability Transition Pore in Mitochondria Devoid of Cyclophilin D | Journal of Biological Chemistry | 2005 | 723 |
27 | The Function of α-Synuclein | Neuron | 2013 | 703 |
28 | Selective elimination of glutamatergic synapses on striatopallidal neurons in Parkinson disease models | Nature Neuroscience | 2006 | 688 |
29 | PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress | Cell Death and Differentiation | 2012 | 656 |
30 | Endoplasmic reticulum stress signalling and the pathogenesis of non-alcoholic fatty liver disease | Journal of Hepatology | 2018 | 638 |
31 | Proteostasis control by the unfolded protein response | Nature Cell Biology | 2015 | 612 |
32 | Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases | Nature Reviews Neuroscience | 2014 | 609 |
33 | A Cacna1a Knockin Migraine Mouse Model with Increased Susceptibility to Cortical Spreading Depression | Neuron | 2004 | 602 |
34 | LPA receptor signaling: pharmacology, physiology, and pathophysiology | Journal of Lipid Research | 2014 | 580 |
35 | FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P 1 ) modulation | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 566 |
36 | Regulation of autophagy and the ubiquitin–proteasome system by the FoxO transcriptional network during muscle atrophy | Nature Communications | 2015 | 549 |
37 | Microglia Induce Motor Neuron Death via the Classical NF-κB Pathway in Amyotrophic Lateral Sclerosis | Neuron | 2014 | 547 |
38 | Pathophysiology of Migraine | Annual Review of Physiology | 2013 | 544 |
39 | Botulinum Neurotoxins: Biology, Pharmacology, and Toxicology | Pharmacological Reviews | 2017 | 544 |
40 | Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis | Nature Reviews Neurology | 2011 | 530 |
41 | Prolonged myelination in human neocortical evolution | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 517 |
42 | The genetic architecture of the human cerebral cortex | Science | 2020 | 517 |
43 | Interaction between flavonoids and the blood–brain barrier: in vitro studies | Journal of Neurochemistry | 2003 | 509 |
44 | Flavonoid permeability across an in situ model of the blood–brain barrier | Free Radical Biology and Medicine | 2004 | 509 |
45 | The Unfolded Protein Response: Integrating Stress Signals Through the Stress Sensor IRE1α | Physiological Reviews | 2011 | 509 |
46 | The ubiquitin ligase parkin mediates resistance to intracellular pathogens | Nature | 2013 | 499 |
47 | Functional regeneration of sensory axons into the adult spinal cord | Nature | 2000 | 494 |
48 | The Mitochondrial Permeability Transition Pore: Channel Formation by F-ATP Synthase, Integration in Signal Transduction, and Role in Pathophysiology | Physiological Reviews | 2015 | 493 |
49 | Lipid Rafts Mediate the Synaptic Localization of -Synuclein | Journal of Neuroscience | 2004 | 492 |
50 | Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling | Nature Medicine | 2004 | 487 |