| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 2 | G Protein-Coupled Receptor Allosterism and Complexing | Pharmacological Reviews | 2002 | 833 |
| 3 | Allosteric Modulation of G Protein–Coupled Receptors | Annual Review of Pharmacology and Toxicology | 2007 | 615 |
| 4 | Allosteric binding sites on cell-surface receptors: novel targets for drug discovery | Nature Reviews Drug Discovery | 2002 | 574 |
| 5 | PI 3-kinase p110β: a new target for antithrombotic therapy | Nature Medicine | 2005 | 555 |
| 6 | Reactive Oxygen Species Enhance Insulin Sensitivity | Cell Metabolism | 2009 | 509 |
| 7 | Multiple Amylin Receptors Arise from Receptor Activity-Modifying Protein Interaction with the Calcitonin Receptor Gene Product | Molecular Pharmacology | 1999 | 456 |
| 8 | The contribution of astrocytes and microglia to traumatic brain injury | British Journal of Pharmacology | 2016 | 447 |
| 9 | Endothelium-dependent hyperpolarization: a role in the control of vascular tone | Trends in Pharmacological Sciences | 1995 | 432 |
| 10 | Avoidance of Nitrous Oxide for Patients Undergoing Major Surgery | Anesthesiology | 2007 | 397 |
| 11 | Bacterial membrane vesicles deliver peptidoglycan to NOD1 in epithelial cells | Cellular Microbiology | 2010 | 382 |
| 12 | Nitric oxide and vasoactive intestinal polypeptide mediate non-adrenergic, non-cholinergic inhibitory transmission to smooth muscle of the rat gastric fundus | European Journal of Pharmacology | 1990 | 364 |
| 13 | NITRERGIC TRANSMISSION: NITRIC OXIDE AS A MEDIATOR OF NON-ADRENERGIC, NON-CHOLINERGIC NEURO-EFFECTOR TRANSMISSION | Clinical and Experimental Pharmacology and Physiology | 1992 | 359 |
| 14 | A protective role for protease-activated receptors in the airways | Nature | 1999 | 345 |
| 15 | Acute pulmonary oedema in pregnant women | Anaesthesia | 2012 | 326 |
| 16 | Molecular Evolution and Phylogeny of Elapid Snake Venom Three-Finger Toxins | Journal of Molecular Evolution | 2003 | 319 |
| 17 | The Global Snake Bite Initiative: an antidote for snake bite | Lancet, The | 2010 | 306 |
| 18 | Novel Receptor Partners and Function of Receptor Activity-modifying Proteins | Journal of Biological Chemistry | 2003 | 283 |
| 19 | Evidence that part of the NANC relaxant response of guinea‐pig trachea to electrical field stimulation is mediated by nitric oxide | British Journal of Pharmacology | 1991 | 278 |
| 20 | Snakebite envenoming from a global perspective: Towards an integrated approach | Toxicon | 2010 | 268 |
| 21 | Cigarette Smoking and Plasma Levels of Nicotine | Nature | 1972 | 263 |
| 22 | Interaction between glucocorticoids and β 2 agonists on bronchial airway smooth muscle cells through synchronised cellular signalling | Lancet, The | 2002 | 261 |
| 23 | Purinergic Signaling and Blood Vessels in Health and Disease | Pharmacological Reviews | 2014 | 251 |
| 24 | Neuroinflammation and oxidative stress: Co-conspirators in the pathology of Parkinson’s disease | Neurochemistry International | 2013 | 250 |
| 25 | Management of pre‐eclampsia: issues for anaesthetists | Anaesthesia | 2012 | 248 |
| 26 | Transient neuroprotection by minocycline following traumatic brain injury is associated with attenuated microglial activation but no changes in cell apoptosis or neutrophil infiltration | Experimental Neurology | 2007 | 224 |
| 27 | Potassium Channel Function in Vascular Disease | Arteriosclerosis, Thrombosis, and Vascular Biology | 2001 | 222 |
| 28 | N-acetylcysteine attenuates the decline in muscle Na+,K+-pump activity and delays fatigue during prolonged exercise in humans | Journal of Physiology | 2006 | 216 |
| 29 | Cardiac Tissue Engineering in an In Vivo Vascularized Chamber | Circulation | 2007 | 216 |
| 30 | Inhibition of Nox2 Oxidase Activity Ameliorates Influenza A Virus-Induced Lung Inflammation | PLoS Pathogens | 2011 | 210 |
| 31 | Protease-activated receptors: sentries for inflammation? | Trends in Pharmacological Sciences | 2000 | 207 |
| 32 | Assembling an Arsenal: Origin and Evolution of the Snake Venom Proteome Inferred from Phylogenetic Analysis of Toxin Sequences | Molecular Biology and Evolution | 2004 | 206 |
| 33 | Ending the drought: New strategies for improving the flow of affordable, effective antivenoms in Asia and Africa | Journal of Proteomics | 2011 | 206 |
| 34 | Review: Role of developmental inflammation and blood–brain barrier dysfunction in neurodevelopmental and neurodegenerative diseases | Neuropathology and Applied Neurobiology | 2009 | 204 |
| 35 | Biased Signaling of Protease-Activated Receptors | Frontiers in Endocrinology | 2014 | 201 |
| 36 | NADPH Oxidase Activity and Function Are Profoundly Greater in Cerebral Versus Systemic Arteries | Circulation Research | 2005 | 198 |
| 37 | Changes in blood-brain barrier permeability to large and small molecules following traumatic brain injury in mice | European Journal of Neuroscience | 2007 | 197 |
| 38 | Muscarinic receptor subtypes in human bladder detrusor and mucosa, studied by radioligand binding and quantitative competitive RT-PCR: changes in ageing | British Journal of Pharmacology | 2005 | 196 |
| 39 | Purinergic signalling: from discovery to current developments | Experimental Physiology | 2014 | 195 |
| 40 | A Randomized Phase II Trial of Granulocyte-Macrophage Colony-Stimulating Factor Therapy in Severe Sepsis with Respiratory Dysfunction | American Journal of Respiratory and Critical Care Medicine | 2002 | 192 |
| 41 | Development and Feasibility of a Scale to Assess Postoperative Recovery | Anesthesiology | 2010 | 192 |
| 42 | Barriers in the brain: a renaissance? | Trends in Neurosciences | 2008 | 191 |
| 43 | Australian venomous jellyfish, envenomation syndromes, toxins and therapy | Toxicon | 2006 | 189 |
| 44 | Targeting Rho and Rho-kinase in the treatment of cardiovascular disease | Trends in Pharmacological Sciences | 2006 | 188 |
| 45 | EVIDENCE FOR A ROLE OF NITRIC OXIDE IN THE NEUROTRANSMITTER SYSTEM MEDIATING RELAXATION OF THE RAT ANOCOCCYGEUS MUSCLEC | Clinical and Experimental Pharmacology and Physiology | 1989 | 183 |
| 46 | Estrogen deficiency causes central leptin insensitivity and increased hypothalamic neuropeptide Y | International Journal of Obesity | 2001 | 182 |
| 47 | Refractive index measurement in viable cells using quantitative phase-amplitude microscopy and confocal microscopy | Cytometry Part A: the Journal of the International Society for Analytical Cytology | 2005 | 177 |
| 48 | VASCULAR AND ANTI-OXIDANT ACTIONS OF FLAVONOLS AND FLAVONES | Clinical and Experimental Pharmacology and Physiology | 2004 | 176 |
| 49 | The rise and spread ofmcrplasmid-mediated polymyxin resistance | Critical Reviews in Microbiology | 2019 | 174 |
| 50 | Receptor activity modifying proteins | Cellular Signalling | 2001 | 166 |
