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Top Articles

#TitleJournalYearCitations
1Multiplatform Analysis of 12 Cancer Types Reveals Molecular Classification within and across Tissues of OriginCell20141,242
2Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexesNature Genetics2015830
3Geriatric muscle stem cells switch reversible quiescence into senescenceNature2014785
4Non-coding recurrent mutations in chronic lymphocytic leukaemiaNature2015749
5Ion channels enable electrical communication in bacterial communitiesNature2015527
6IntOGen-mutations identifies cancer drivers across tumor typesNature Methods2013517
7Complex photonics: Dynamics and applications of delay-coupled semiconductors lasersReviews of Modern Physics2013478
8Genomic insights into the Ixodes scapularis tick vector of Lyme diseaseNature Communications2016450
9Comprehensive identification of mutational cancer driver genes across 12 tumor typesScientific Reports2013437
10Metabolic co-dependence gives rise to collective oscillations within biofilmsNature2015393
11The Dawn of Human Matrilineal DiversityAmerican Journal of Human Genetics2008392
12The asthma-associated ORMDL3 gene product regulates endoplasmic reticulum-mediated calcium signaling and cellular stressHuman Molecular Genetics2010317
13Precarious employment and health: developing a research agendaJournal of Epidemiology and Community Health2007311
14Biologic Therapies and Risk of Infection and Malignancy in Patients With Inflammatory Bowel Disease: A Systematic Review and Network Meta-analysisClinical Gastroenterology and Hepatology2016303
15Preterm birth, infant weight gain, and childhood asthma risk: A meta-analysis of 147,000 European childrenJournal of Allergy and Clinical Immunology2014285
16Mfn2 deficiency links age‐related sarcopenia and impaired autophagy to activation of an adaptive mitophagy pathwayEMBO Journal2016275
17Signalling pathways regulating muscle mass in ageing skeletal muscle. The role of the IGF1-Akt-mTOR-FoxO pathwayBiogerontology2013274
18A Pan-cancer Landscape of Interactions between Solid Tumors and Infiltrating Immune Cell PopulationsClinical Cancer Research2018267
19Human Cytomegalovirus Infection Is Associated with Increased Proportions of NK Cells That Express the CD94/NKG2C Receptor in Aviremic HIV‐1–Positive PatientsJournal of Infectious Diseases2006261
20A Neutrophil Timer Coordinates Immune Defense and Vascular ProtectionImmunity2019258
21Gitools: Analysis and Visualisation of Genomic Data Using Interactive Heat-MapsPLoS ONE2011252
22Pregnenolone Can Protect the Brain from Cannabis IntoxicationScience2014247
23Risk of infections using anti-TNF agents in rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis: a systematic review and meta-analysisExpert Opinion on Drug Safety2016235
24Green space, health inequality and pregnancyEnvironment International2012223
25p38/MKP-1–regulated AKT coordinates macrophage transitions and resolution of inflammation during tissue repairJournal of Cell Biology2011206
26Escherichia coli Cell Surface Perturbation and Disruption Induced by Antimicrobial Peptides BP100 and pepRJournal of Biological Chemistry2010193
27Coupling between distant biofilms and emergence of nutrient time-sharingScience2017192
28Connecting Peptide Physicochemical and Antimicrobial Properties by a Rational Prediction ModelPLoS ONE2011185
29Surrounding Greenness and Exposure to Air Pollution During Pregnancy: An Analysis of Personal Monitoring DataEnvironmental Health Perspectives2012183
30Independent Component Analysis Uncovers the Landscape of the Bladder Tumor Transcriptome and Reveals Insights into Luminal and Basal SubtypesCell Reports2014181
31TRPV4 channel participates in receptor-operated calcium entry and ciliary beat frequency regulation in mouse airway epithelial cellsProceedings of the National Academy of Sciences of the United States of America2008176
32Transcriptome characterization by RNA sequencing identifies a major molecular and clinical subdivision in chronic lymphocytic leukemiaGenome Research2014175
33Paternally inherited cis-regulatory structural variants are associated with autismScience2018174
34Associations between temporary employment and occupational injury: what are the mechanisms?Occupational and Environmental Medicine2006173
35Species-specific segmentation clock periods are due to differential biochemical reaction speedsScience2020169
36Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergeticsNature Cell Biology2019168
37Dual function of C/D box small nucleolar RNAs in rRNA modification and alternative pre-mRNA splicingProceedings of the National Academy of Sciences of the United States of America2016160
38Piezo2 channel regulates RhoA and actin cytoskeleton to promote cell mechanobiological responsesProceedings of the National Academy of Sciences of the United States of America2018158
39Membrane Protein Structure, Function, and Dynamics: a Perspective from Experiments and TheoryJournal of Membrane Biology2015157
40Hypocretins Regulate the Anxiogenic-Like Effects of Nicotine and Induce Reinstatement of Nicotine-Seeking BehaviorJournal of Neuroscience2010153
41The Mnks: MAP kinase-interacting kinases (MAP kinase signal-integrating kinases)Frontiers in Bioscience - Landmark2008149
42Antiviral drug discovery: broad-spectrum drugs from natureNatural Product Reports2015148
43Cellular and Molecular Mechanisms Regulating Fibrosis in Skeletal Muscle Repair and DiseaseCurrent Topics in Developmental Biology2011147
44Gene expression induced by Toll-like receptors in macrophages requires the transcription factor NFAT5Journal of Experimental Medicine2012143
45Restoration of muscle strength in dystrophic muscle by angiotensin-1-7 through inhibition of TGF-β signallingHuman Molecular Genetics2014143
46Evaluating the Genetics of Common Variable Immunodeficiency: Monogenetic Model and BeyondFrontiers in Immunology2018142
47Integrating genomic alterations in diffuse large B-cell lymphoma identifies new relevant pathways and potential therapeutic targetsLeukemia2018141
48Effects of an integrated care intervention on risk factors of COPD readmissionRespiratory Medicine2007140
49AMPA: an automated web server for prediction of protein antimicrobial regionsBioinformatics2012140
50Activation of GCN2 kinase by ribosome stalling links translation elongation with translation initiationELife2016139