# | Title | Journal | Year | Citations |
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1 | Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1 | Nature Medicine | 2006 | 1,129 |
2 | Regression of Metastatic Renal-Cell Carcinoma after Nonmyeloablative Allogeneic Peripheral-Blood Stem-Cell Transplantation | New England Journal of Medicine | 2000 | 977 |
3 | Parvovirus B19 | New England Journal of Medicine | 2004 | 817 |
4 | Telomere Diseases | New England Journal of Medicine | 2009 | 723 |
5 | Augmented Wnt Signaling in a Mammalian Model of Accelerated Aging | Science | 2007 | 683 |
6 | Mutations inTERT,the Gene for Telomerase Reverse Transcriptase, in Aplastic Anemia | New England Journal of Medicine | 2005 | 665 |
7 | Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3 | EMBO Journal | 2000 | 567 |
8 | Chromatin Signatures in Multipotent Human Hematopoietic Stem Cells Indicate the Fate of Bivalent Genes during Differentiation | Cell Stem Cell | 2009 | 548 |
9 | Retrovirally marked CD34-enriched peripheral blood and bone marrow cells contribute to long-term engraftment after autologous transplantation | Blood | 1995 | 493 |
10 | Fas antigen expression on CD34+ human marrow cells is induced by interferon gamma and tumor necrosis factor alpha and potentiates cytokine-mediated hematopoietic suppression in vitro | Blood | 1995 | 491 |
11 | ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex | Proceedings of the National Academy of Sciences of the United States of America | 1998 | 490 |
12 | The Pathophysiology of Acquired Aplastic Anemia | New England Journal of Medicine | 1997 | 475 |
13 | Eltrombopag and Improved Hematopoiesis in Refractory Aplastic Anemia | New England Journal of Medicine | 2012 | 454 |
14 | Human thrombopoietin levels are high when thrombocytopenia is due to megakaryocyte deficiency and low when due to increased platelet destruction | Blood | 1996 | 435 |
15 | Bmi1 regulates mitochondrial function and the DNA damage response pathway | Nature | 2009 | 420 |
16 | Horse versus Rabbit Antithymocyte Globulin in Acquired Aplastic Anemia | New England Journal of Medicine | 2011 | 415 |
17 | Early cytomegalovirus reactivation remains associated with increased transplant-related mortality in the current era: a CIBMTR analysis | Blood | 2016 | 403 |
18 | Mantle cell lymphoma: biology, pathogenesis, and the molecular basis of treatment in the genomic era | Blood | 2011 | 368 |
19 | Antithymocyte Globulin and Cyclosporine for Severe Aplastic Anemia | JAMA - Journal of the American Medical Association | 2003 | 353 |
20 | How I treat acquired aplastic anemia | Blood | 2012 | 351 |
21 | Why Current Publication Practices May Distort Science | PLoS Medicine | 2008 | 345 |
22 | Ibrutinib for previously untreated and relapsed or refractory chronic lymphocytic leukaemia with TP53 aberrations: a phase 2, single-arm trial | Lancet Oncology, The | 2015 | 344 |
23 | Leukemia-associated antigen-specific T-cell responses following combined PR1 and WT1 peptide vaccination in patients with myeloid malignancies | Blood | 2008 | 337 |
24 | Eltrombopag restores trilineage hematopoiesis in refractory severe aplastic anemia that can be sustained on discontinuation of drug | Blood | 2014 | 336 |
25 | High donor FOXP3-positive regulatory T-cell (Treg) content is associated with a low risk of GVHD following HLA-matched allogeneic SCT | Blood | 2006 | 333 |
26 | Resistance to Parvovirus B19 Infection Due to Lack of Virus Receptor (Erythrocyte P Antigen) | New England Journal of Medicine | 1994 | 330 |
27 | Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia | Cell | 2018 | 323 |
28 | Regulation of CSF1 Promoter by the SWI/SNF-like BAF Complex | Cell | 2001 | 315 |
29 | Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells | Blood | 2009 | 312 |
30 | Cellular Constituents of Immune Escape within the Tumor Microenvironment | Cancer Research | 2012 | 308 |
31 | Intensive immunosuppression with antithymocyte globulin and cyclosporine as treatment for severe acquired aplastic anemia | Blood | 1995 | 306 |
32 | ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 305 |
33 | 2021 Update on MRD in acute myeloid leukemia: a consensus document from the European LeukemiaNet MRD Working Party | Blood | 2021 | 305 |
34 | Binding of Adeno-associated Virus Type 5 to 2,3-Linked Sialic Acid Is Required for Gene Transfer | Journal of Biological Chemistry | 2001 | 304 |
35 | Genome-wide detection of DNase I hypersensitive sites in single cells and FFPE tissue samples | Nature | 2015 | 303 |
36 | Targeting B cell receptor signalling in cancer: preclinical and clinical advances | Nature Reviews Cancer | 2018 | 299 |
37 | Hepatitis-Associated Aplastic Anemia | New England Journal of Medicine | 1997 | 293 |
38 | Mitochondrial Membrane Potential Identifies Cells with Enhanced Stemness for Cellular Therapy | Cell Metabolism | 2016 | 291 |
39 | Long-term Safety and Efficacy Following Systemic Administration of a Self-complementary AAV Vector Encoding Human FIX Pseudotyped With Serotype 5 and 8 Capsid Proteins | Molecular Therapy | 2011 | 280 |
40 | Genotoxicity of Retroviral Integration In Hematopoietic Cells | Molecular Therapy | 2006 | 276 |
41 | Clonal evolution leading to ibrutinib resistance in chronic lymphocytic leukemia | Blood | 2017 | 276 |
42 | Mutations of the human telomerase RNA gene (TERC) in aplastic anemia and myelodysplastic syndrome | Blood | 2003 | 274 |
43 | Human Parvoviruses | Clinical Microbiology Reviews | 2017 | 258 |
44 | Ex Vivo Expansion of Genetically Marked Rhesus Peripheral Blood Progenitor Cells Results in Diminished Long-Term Repopulating Ability | Blood | 1998 | 252 |
45 | Label-Free Protein Quantification Using LC-Coupled Ion Trap or FT Mass Spectrometry: Reproducibility, Linearity, and Application with Complex Proteomes | Journal of Proteome Research | 2006 | 244 |
46 | Late presentation of dyskeratosis congenita as apparently acquired aplastic anaemia due to mutations in telomerase RNA | Lancet, The | 2003 | 239 |
47 | The distribution of T‐cell subsets and the expression of immune checkpoint receptors and ligands in patients with newly diagnosed and relapsed acute myeloid leukemia | Cancer | 2019 | 229 |
48 | In-vivo dominant immune responses in aplastic anaemia: molecular tracking of putatively pathogenetic T-cell clones by TCR β-CDR3 sequencing | Lancet, The | 2004 | 223 |
49 | Aplastic anemia | Current Opinion in Hematology | 2008 | 223 |
50 | Bone marrow failure and the telomeropathies | Blood | 2014 | 222 |