| # | Title | Journal | Year | Citations |
|---|
| 1 | Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma | Cell | 2016 | 1,695 |
| 2 | The role of microRNA genes in papillary thyroid carcinoma | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 1,137 |
| 3 | The Chemistry of Neutron Capture Therapy | Chemical Reviews | 1998 | 1,130 |
| 4 | Effect of Fixatives and Tissue Processing on the Content and Integrity of Nucleic Acids | American Journal of Pathology | 2002 | 1,109 |
| 5 | Boron Neutron Capture Therapy of Cancer: Current Status and Future Prospects | Clinical Cancer Research | 2005 | 882 |
| 6 | The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutic target for CT-011, a novel monoclonal anti–PD-1 antibody | Blood | 2010 | 716 |
| 7 | The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia | Nature Genetics | 2017 | 693 |
| 8 | Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma | Cancer Cell | 2017 | 642 |
| 9 | Interleukin-6 induces an epithelial–mesenchymal transition phenotype in human breast cancer cells | Oncogene | 2009 | 640 |
| 10 | Cytogenetics in acute leukemia | Blood Reviews | 2004 | 600 |
| 11 | microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer | Oncogene | 2011 | 600 |
| 12 | Digital pathology and artificial intelligence | Lancet Oncology, The | 2019 | 597 |
| 13 | Vascular Endothelial Growth Factor and Angiogenesis in the Regulation of Cutaneous Wound Repair | Advances in Wound Care | 2014 | 589 |
| 14 | Downregulation of miR-122 in the rodent and human hepatocellular carcinomas | Journal of Cellular Biochemistry | 2006 | 575 |
| 15 | Phosphatidylinositol 3-kinase-δ inhibitor CAL-101 shows promising preclinical activity in chronic lymphocytic leukemia by antagonizing intrinsic and extrinsic cellular survival signals | Blood | 2010 | 523 |
| 16 | Etiology of Ibrutinib Therapy Discontinuation and Outcomes in Patients With Chronic Lymphocytic Leukemia | JAMA Oncology | 2015 | 498 |
| 17 | Identification of Proximal Spinal Muscular Atrophy Carriers and Patients by Analysis of SMNT and SMNC Gene Copy Number | American Journal of Human Genetics | 1997 | 494 |
| 18 | The Broad Spectrum of Human Natural Killer Cell Diversity | Immunity | 2017 | 485 |
| 19 | Clinical response and miR-29b predictive significance in older AML patients treated with a 10-day schedule of decitabine | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 443 |
| 20 | MicroRNA-122 Inhibits Tumorigenic Properties of Hepatocellular Carcinoma Cells and Sensitizes These Cells to Sorafenib | Journal of Biological Chemistry | 2009 | 441 |
| 21 | Ibrutinib as initial therapy for elderly patients with chronic lymphocytic leukaemia or small lymphocytic lymphoma: an open-label, multicentre, phase 1b/2 trial | Lancet Oncology, The | 2014 | 438 |
| 22 | Stress, loneliness, and changes in herpesvirus latency | Journal of Behavioral Medicine | 1985 | 433 |
| 23 | A Novel Polymorphism in the MCP-1 Gene Regulatory Region That Influences MCP-1 Expression | Biochemical and Biophysical Research Communications | 1999 | 433 |
| 24 | mRNA Destabilization Is the Dominant Effect of Mammalian MicroRNAs by the Time Substantial Repression Ensues | Molecular Cell | 2014 | 424 |
| 25 | Risk- and response-based classification of childhood B-precursor acute lymphoblastic leukemia: a combined analysis of prognostic markers from the Pediatric Oncology Group (POG) and Children's Cancer Group (CCG) | Blood | 2007 | 413 |
| 26 | Gene expression in papillary thyroid carcinoma reveals highly consistent profiles | Proceedings of the National Academy of Sciences of the United States of America | 2001 | 399 |
| 27 | MicroRNA-21 is Overexpressed in Pancreatic Cancer and a Potential Predictor of Survival | Journal of Gastrointestinal Surgery | 2008 | 394 |
| 28 | Long-term follow-up of imatinib in pediatric Philadelphia chromosome-positive acute lymphoblastic leukemia: Children's Oncology Group Study AALL0031 | Leukemia | 2014 | 384 |
| 29 | Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study | Blood | 2009 | 383 |
| 30 | IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer | Gut | 2018 | 381 |
| 31 | Neutrophils and Wound Repair: Positive Actions and Negative Reactions | Advances in Wound Care | 2013 | 379 |
| 32 | Current status of boron neutron capture therapy of high grade gliomas and recurrent head and neck cancer | Radiation Oncology | 2012 | 375 |
| 33 | Alemtuzumab is an effective therapy for chronic lymphocytic leukemia with p53 mutations and deletions | Blood | 2004 | 370 |
| 34 | Flavopiridol administered using a pharmacologically derived schedule is associated with marked clinical efficacy in refractory, genetically high-risk chronic lymphocytic leukemia | Blood | 2007 | 367 |
| 35 | Preoperative Modified FOLFIRINOX Treatment Followed by Capecitabine-Based Chemoradiation for Borderline Resectable Pancreatic Cancer | JAMA Surgery | 2016 | 365 |
| 36 | Rat brain tumor models in experimental neuro-oncology: the C6, 9L, T9, RG2, F98, BT4C, RT-2 and CNS-1 gliomas | Journal of Neuro-Oncology | 2009 | 353 |
| 37 | A Human CD34(+) Subset Resides in Lymph Nodes and Differentiates into CD56brightNatural Killer Cells | Immunity | 2005 | 331 |
| 38 | Rat brain tumor models in experimental neuro-oncology: the 9L, C6, T9, F98, RG2 (D74), RT-2 and CNS-1 gliomas | | 1998 | 321 |
| 39 | Experimental validation of miRNA targets | Methods | 2008 | 315 |
| 40 | Human Cytomegalovirus Inhibits Major Histocompatibility Complex Class II Expression By Disruption of the Jak/Stat Pathway | Journal of Experimental Medicine | 1998 | 305 |
| 41 | Sphingosine Kinase-1 Expression Correlates With Poor Survival of Patients With Glioblastoma Multiforme: Roles of Sphingosine Kinase Isoforms in Growth of Glioblastoma Cell Lines | Journal of Neuropathology and Experimental Neurology | 2005 | 297 |
| 42 | Molecular analysis of spinal muscular atrophy and modification of the phenotype by SMN2 | Genetics in Medicine | 2002 | 296 |
| 43 | Role for Activating Transcription Factor 3 in Stress-Induced β-Cell Apoptosis | Molecular and Cellular Biology | 2004 | 287 |
| 44 | Criteria for the diagnosis of lupus anticoagulants: an update. On behalf of the Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibody of the Scientific and Standardisation Committee of the ISTH | Thrombosis and Haemostasis | 1995 | 286 |
| 45 | Boron neutron capture therapy for cancer. Realities and prospects | Cancer | 1992 | 279 |
| 46 | Role of microRNA-155 at early stages of hepatocarcinogenesis induced by choline-deficient and amino acid-defined diet in C57BL/6 mice | Hepatology | 2009 | 274 |
| 47 | Boron delivery agents for neutron capture therapy of cancer | Cancer Communications | 2018 | 266 |
| 48 | The immunoregulatory role of dopamine: An update | Brain, Behavior, and Immunity | 2010 | 265 |
| 49 | Computational pathology definitions, best practices, and recommendations for regulatory guidance: a white paper from the Digital Pathology Association | Journal of Pathology | 2019 | 263 |
| 50 | Regulation of scar formation by vascular endothelial growth factor | Laboratory Investigation | 2008 | 261 |
