| # | Title | Journal | Year | Citations |
|---|
| 1 | Gene Expression Levels and Immunolocalization of Organic Ion Transporters in the Human Kidney | Journal of the American Society of Nephrology: JASN | 2002 | 450 |
| 2 | Cellular and molecular aspects of drug transport in the kidney | Kidney International | 2000 | 404 |
| 3 | Identification and Functional Characterization of a New Human Kidney–Specific H+/Organic Cation Antiporter, Kidney-Specific Multidrug and Toxin Extrusion 2 | Journal of the American Society of Nephrology: JASN | 2006 | 348 |
| 4 | Three distinct subpopulations of GABAergic neurons in rat frontal agranular cortex | Brain Research | 1994 | 342 |
| 5 | cDNA Cloning and Functional Expression of a Novel Rat Kidney Organic Cation Transporter, OCT2 | Biochemical and Biophysical Research Communications | 1996 | 335 |
| 6 | Metformin is a Superior Substrate for Renal Organic Cation Transporter OCT2 rather than Hepatic OCT1 | Drug Metabolism and Pharmacokinetics | 2005 | 313 |
| 7 | Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK1) | Journal of Pharmacology and Experimental Therapeutics | 1992 | 261 |
| 8 | Differential contribution of organic cation transporters, OCT2 and MATE1, in platinum agent-induced nephrotoxicity | Biochemical Pharmacology | 2007 | 217 |
| 9 | Immuno-Localization of H+/Peptide Cotransporter in Rat Digestive Tract | Biochemical and Biophysical Research Communications | 1996 | 213 |
| 10 | Effect of clarithromycin on renal excretion of digoxin: Interaction with P-glycoprotein* | Clinical Pharmacology and Therapeutics | 1998 | 201 |
| 11 | C3435T polymorphism in the MDR1 gene affects the enterocyte expression level of CYP3A4 rather than Pgp in recipients of living-donor liver transplantation | Pharmacogenetics and Genomics | 2002 | 186 |
| 12 | Cloning and characterization of a rat H+/peptide cotransporter mediating absorption of beta-lactam antibiotics in the intestine and kidney | Journal of Pharmacology and Experimental Therapeutics | 1995 | 185 |
| 13 | Cloning and Functional Characterization of a Novel Rat Organic Anion Transporter Mediating Basolateral Uptake of Methotrexate in the Kidney | Journal of Biological Chemistry | 1996 | 182 |
| 14 | CYP3A5*1-carrying graft liver reduces the concentration/oral dose ratio of tacrolimus in recipients of living-donor liver transplantation | Pharmacogenetics and Genomics | 2004 | 182 |
| 15 | Creatinine Transport by Basolateral Organic Cation Transporter hOCT2 in the Human Kidney | Pharmaceutical Research | 2004 | 180 |
| 16 | Disruption of multidrug and toxin extrusion MATE1 potentiates cisplatin-induced nephrotoxicity | Biochemical Pharmacology | 2010 | 180 |
| 17 | Renal Transport of Adefovir, Cidofovir, and Tenofovir by SLC22A Family Members (hOAT1, hOAT3, and hOCT2) | Pharmaceutical Research | 2007 | 174 |
| 18 | Genetic polymorphism of the CYP2C subfamily and its effect on the pharmacokinetics of phenytoin in Japanese patients with epilepsy* | Clinical Pharmacology and Therapeutics | 1997 | 170 |
| 19 | (Section A: Molecular, Structural, and Cellular Biology of Drug Transporters) Peptide Transporters: Structure, Function, Regulation and Application for Drug Delivery | Current Drug Metabolism | 2004 | 167 |
| 20 | Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs | Journal of Pharmacology and Experimental Therapeutics | 1998 | 165 |
| 21 | Importance of the multidrug and toxin extrusion MATE/SLC47A family to pharmacokinetics, pharmacodynamics/toxicodynamics and pharmacogenomics | British Journal of Pharmacology | 2011 | 155 |
| 22 | Carrier-mediated transport systems of tetraethylammonium in rat renal brush-border and basolateral membrane vesicles | Biochimica Et Biophysica Acta - Biomembranes | 1984 | 152 |
| 23 | Association between tubular toxicity of cisplatin and expression of organic cation transporter rOCT2 (Slc22a2) in the rat | Biochemical Pharmacology | 2005 | 152 |
| 24 | V1a vasopressin receptors maintain normal blood pressure by regulating circulating blood volume and baroreflex sensitivity | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 149 |
| 25 | Gender differences in expression of organic cation transporter OCT2 in rat kidney | FEBS Letters | 1999 | 148 |
| 26 | Organic cation transporter OCT/SLC22A and H+/organic cation antiporter MATE/SLC47A are key molecules for nephrotoxicity of platinum agents | Biochemical Pharmacology | 2011 | 148 |
| 27 | Molecular cloning and tissue distribution of rat peptide transporter PEPT2 | Biochimica Et Biophysica Acta - Biomembranes | 1996 | 135 |
| 28 | Down-regulation of rat organic cation transporter rOCT2 by 5/6 nephrectomy | Kidney International | 2002 | 132 |
| 29 | Physiological and pharmacokinetic roles of H+/organic cation antiporters (MATE/SLC47A) | Biochemical Pharmacology | 2008 | 131 |
| 30 | Accumulation of arginine-rich cell-penetrating peptides in tumors and the potential for anticancer drug delivery in vivo | Journal of Controlled Release | 2012 | 131 |
| 31 | Identification and functional characterization of a novel human and rat riboflavin transporter, RFT1 | American Journal of Physiology - Cell Physiology | 2008 | 126 |
| 32 | Hormonal regulation of organic cation transporter OCT2 expression in rat kidney | FEBS Letters | 2000 | 125 |
| 33 | Effect of intestinal CYP3A5 on postoperative tacrolimus trough levels in living-donor liver transplant recipients | Pharmacogenetics and Genomics | 2006 | 125 |
| 34 | Novel riboflavin transporter family RFVT/SLC52: Identification, nomenclature, functional characterization and genetic diseases of RFVT/SLC52 | Molecular Aspects of Medicine | 2013 | 125 |
| 35 | Functional characterization of the rat multispecific organic anion transporter OAT1 mediating basolateral uptake of anionic drugs in the kidney | FEBS Letters | 1998 | 124 |
| 36 | SLCO4C1 Transporter Eliminates Uremic Toxins and Attenuates Hypertension and Renal Inflammation | Journal of the American Society of Nephrology: JASN | 2009 | 124 |
| 37 | Identification and Comparative Functional Characterization of a New Human Riboflavin Transporter hRFT3 Expressed in the Brain | Journal of Nutrition | 2010 | 121 |
| 38 | Nerve growth factor specifically induces human IgG4 production | European Journal of Immunology | 1991 | 116 |
| 39 | cDNA Cloning, Functional Characterization, and Tissue Distribution of an Alternatively Spliced Variant of Organic Cation Transporter hOCT2 Predominantly Expressed in the Human Kidney | Journal of the American Society of Nephrology: JASN | 2002 | 114 |
| 40 | Human organic anion transporter hOAT3 is a potent transporter of cephalosporin antibiotics, in comparison with hOAT1 | Biochemical Pharmacology | 2005 | 114 |
| 41 | Peptide transporter in the rat small intestine: ultrastructural localization and the effect of starvation and administration of amino acids | The Histochemical Journal | 1999 | 103 |
| 42 | Cloning and functional characterization of a new multispecific organic anion transporter, OAT-K2, in rat kidney | Molecular Pharmacology | 1999 | 102 |
| 43 | INNO-406, a novel BCR-ABL/Lyn dual tyrosine kinase inhibitor, suppresses the growth of Ph+ leukemia cells in the central nervous system, and cyclosporine A augments its in vivo activity | Blood | 2007 | 100 |
| 44 | The Diurnal Rhythm of the Intestinal Transporters SGLT1 and PEPT1 Is Regulated by the Feeding Conditions in Rats | Journal of Nutrition | 2004 | 99 |
| 45 | Expression Levels of Renal Organic Anion Transporters (OATs) and Their Correlation with Anionic Drug Excretion in Patients with Renal Diseases | Pharmaceutical Research | 2004 | 95 |
| 46 | Diurnal rhythm of H+-peptide cotransporter in rat small intestine | American Journal of Physiology - Renal Physiology | 2002 | 94 |
| 47 | Population pharmacokinetic and pharmacogenomic analysis of tacrolimus in pediatric living-donor liver transplant recipients | Clinical Pharmacology and Therapeutics | 2006 | 93 |
| 48 | Structural requirements for determining the substrate affinity of peptide transporters PEPT1 and PEPT2 | Pflugers Archiv European Journal of Physiology | 2000 | 91 |
| 49 | Impact of MDR1 and CYP3A5 on the oral clearance of tacrolimus and tacrolimus-related renal dysfunction in adult living-donor liver transplant patients | Pharmacogenetics and Genomics | 2008 | 91 |
| 50 | UGT1A1*6 polymorphism is most predictive of severe neutropenia induced by irinotecan in Japanese cancer patients | International Journal of Clinical Oncology | 2009 | 90 |
