| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 3 | Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2016 for the treatment of colorectal cancer | International Journal of Clinical Oncology | 2018 | 1,187 |
| 4 | Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2019 for the treatment of colorectal cancer | International Journal of Clinical Oncology | 2020 | 1,123 |
| 5 | Neuronal Subtype-Specific Genes that Control Corticospinal Motor Neuron Development In Vivo | Neuron | 2005 | 1,046 |
| 6 | In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses | Nature | 2009 | 1,002 |
| 7 | The ProteomeXchange consortium in 2017: supporting the cultural change in proteomics public data deposition | Nucleic Acids Research | 2017 | 860 |
| 8 | Inhibition of Vascular Endothelial Growth Factor (VEGF) Signaling in Cancer Causes Loss of Endothelial Fenestrations, Regression of Tumor Vessels, and Appearance of Basement Membrane Ghosts | American Journal of Pathology | 2004 | 702 |
| 9 | Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2010 for the treatment of colorectal cancer | International Journal of Clinical Oncology | 2012 | 658 |
| 10 | p62/SQSTM1 functions as a signaling hub and an autophagy adaptor | FEBS Journal | 2015 | 626 |
| 11 | Correlations between lymph node metastasis and depth of submucosal invasion in submucosal invasive colorectal carcinoma: a Japanese collaborative study | Journal of Gastroenterology | 2004 | 603 |
| 12 | Aurora-A and an Interacting Activator, the LIM Protein Ajuba, Are Required for Mitotic Commitment in Human Cells | Cell | 2003 | 563 |
| 13 | Japanese Society for Cancer of the Colon and Rectum (JSCCR) Guidelines 2014 for treatment of colorectal cancer | International Journal of Clinical Oncology | 2015 | 548 |
| 14 | The ProteomeXchange consortium in 2020: enabling ‘big data’ approaches in proteomics | Nucleic Acids Research | 2020 | 491 |
| 15 | Periodontal health and gingival diseases and conditions on an intact and a reduced periodontium: Consensus report of workgroup 1 of the 2017 World Workshop on the Classification of Periodontal and Peri‐Implant Diseases and Conditions | Journal of Periodontology | 2018 | 469 |
| 16 | jPOSTrepo: an international standard data repository for proteomes | Nucleic Acids Research | 2017 | 451 |
| 17 | Predicted expansion of the claudin multigene family | FEBS Letters | 2011 | 432 |
| 18 | Tanycytes of the hypothalamic median eminence form a diet-responsive neurogenic niche | Nature Neuroscience | 2012 | 413 |
| 19 | Collagen Fibers, Reticular Fibers and Elastic Fibers. A Comprehensive Understanding from a Morphological Viewpoint. | Archives of Histology and Cytology | 2002 | 411 |
| 20 | Anatomic Resection Independently Improves Long-Term Survival in Patients with T1–T2 Hepatocellular Carcinoma | Annals of Surgical Oncology | 2007 | 406 |
| 21 | A multicenter retrospective study of endoscopic resection for early gastric cancer | Gastric Cancer | 2006 | 393 |
| 22 | CD4 CTL, a Cytotoxic Subset of CD4+ T Cells, Their Differentiation and Function | Frontiers in Immunology | 2017 | 328 |
| 23 | Platelet-Rich Plasma Contains High Levels of Platelet-Derived Growth Factor and Transforming Growth Factor-β and Modulates the Proliferation of Periodontally Related Cells In Vitro | Journal of Periodontology | 2003 | 319 |
| 24 | Bcl11b is required for differentiation and survival of αβ T lymphocytes | Nature Immunology | 2003 | 317 |
| 25 | Impending Epidemic Future Projection of Heart Failure in Japan to the Year 2055 | Circulation Journal | 2008 | 314 |
| 26 | Periodontal health and gingival diseases and conditions on an intact and a reduced periodontium: Consensus report of workgroup 1 of the 2017 World Workshop on the Classification of Periodontal and Peri‐Implant Diseases and Conditions | Journal of Clinical Periodontology | 2018 | 312 |
| 27 | Periodontal manifestations of systemic diseases and developmental and acquired conditions: Consensus report of workgroup 3 of the 2017 World Workshop on the Classification of Periodontal and Peri‐Implant Diseases and Conditions | Journal of Clinical Periodontology | 2018 | 303 |
| 28 | Excellent Long-term Outcome of ABO-Incompatible Living Donor Kidney Transplantation in Japan | American Journal of Transplantation | 2004 | 297 |
| 29 | Reactive astrocytes function as phagocytes after brain ischemia via ABCA1-mediated pathway | Nature Communications | 2017 | 287 |
| 30 | An Essential Developmental Checkpoint for Production of the T Cell Lineage | Science | 2010 | 274 |
| 31 | Eradication of established tumors in mice by a combination antibody-based therapy | Nature Medicine | 2006 | 248 |
| 32 | Comparison of hydroxyapatite and beta tricalcium phosphate as bone substitutes after excision of bone tumors | Journal of Biomedical Materials Research Part B | 2005 | 246 |
| 33 | Periodontal manifestations of systemic diseases and developmental and acquired conditions: Consensus report of workgroup 3 of the 2017 World Workshop on the Classification of Periodontal and Peri‐Implant Diseases and Conditions | Journal of Periodontology | 2018 | 239 |
| 34 | Preliminary results for avelumab plus axitinib as first-line therapy in patients with advanced clear-cell renal-cell carcinoma (JAVELIN Renal 100): an open-label, dose-finding and dose-expansion, phase 1b trial | Lancet Oncology, The | 2018 | 228 |
| 35 | Both G3BP1 and G3BP2 contribute to stress granule formation | Genes To Cells | 2013 | 222 |
| 36 | p62/SQSTM1 – steering the cell through health and disease | Journal of Cell Science | 2018 | 214 |
| 37 | CENP-A Phosphorylation by Aurora-A in Prophase Is Required for Enrichment of Aurora-B at Inner Centromeres and for Kinetochore Function | Developmental Cell | 2003 | 212 |
| 38 | Clinicopathologic analysis of TAFRO syndrome demonstrates a distinct subtype of HHV‐8‐negative multicentric Castleman disease | American Journal of Hematology | 2016 | 208 |
| 39 | Clinical practice guidelines for the management of biliary tract cancers 2015: the 2nd English edition | Journal of Hepato-Biliary-Pancreatic Sciences | 2015 | 205 |
| 40 | Severity and Frequency of Proximal Tubule Injury Determines Renal Prognosis | Journal of the American Society of Nephrology: JASN | 2016 | 196 |
| 41 | Acceptance of a COVID-19 Vaccine in Japan during the COVID-19 Pandemic | Vaccines | 2021 | 196 |
| 42 | Platelet-Rich Plasma Combined With a Porous Hydroxyapatite Graft for the Treatment of Intrabony Periodontal Defects in Humans: A Comparative Controlled Clinical Study | Journal of Periodontology | 2005 | 192 |
| 43 | Bioactivity evaluation of three calcium silicate‐based endodontic materials | International Endodontic Journal | 2013 | 191 |
| 44 | Platelet-Rich Plasma-Derived Fibrin Clot Formation Stimulates Collagen Synthesis in Periodontal Ligament and Osteoblastic Cells In Vitro | Journal of Periodontology | 2003 | 188 |
| 45 | Prognosis of Japanese Metastatic Renal Cell Carcinoma Patients in the Cytokine Era: A Cooperative Group Report of 1463 Patients | European Urology | 2010 | 180 |
| 46 | Validity of Short and Long Self-Administered Food Frequency Questionnaires in Ranking Dietary Intake in Middle-Aged and Elderly Japanese in the Japan Public Health Center-Based Prospective Study for the Next Generation (JPHC-NEXT) Protocol Area | Journal of Epidemiology | 2016 | 180 |
| 47 | Histological assessment in grafts of highly purified beta-tricalcium phosphate (OSferion®) in human bones | Biomaterials | 2006 | 179 |
| 48 | Application of a new histological staging and grading system for primary biliary cirrhosis to liver biopsy specimens: Interobserver agreement | Pathology International | 2010 | 177 |
| 49 | Cytokine hypothesis of schizophrenia pathogenesis: Evidence from human studies and animal models | Psychiatry and Clinical Neurosciences | 2010 | 177 |
| 50 | The role of genetic polymorphisms in periodontitis | Periodontology 2000 | 2007 | 174 |
