| # | Title | Journal | Year | Citations |
|---|
| 1 | Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease | Nature Genetics | 2013 | 3,741 |
| 2 | Increased reporting of fatal immune checkpoint inhibitor-associated myocarditis | Lancet, The | 2018 | 618 |
| 3 | World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Schizophrenia, Part 2: Update 2012 on the long-term treatment of schizophrenia and management of antipsychotic-induced side effects | World Journal of Biological Psychiatry | 2013 | 343 |
| 4 | PAI-1 and the Metabolic Syndrome | Arteriosclerosis, Thrombosis, and Vascular Biology | 2006 | 326 |
| 5 | Doxorubicin Eliminates Myeloid-Derived Suppressor Cells and Enhances the Efficacy of Adoptive T-Cell Transfer in Breast Cancer | Cancer Research | 2014 | 319 |
| 6 | Sprouty Genes Control Diastema Tooth Development via Bidirectional Antagonism of Epithelial-Mesenchymal FGF Signaling | Developmental Cell | 2006 | 260 |
| 7 | Efficacy and safety of belimumab in primary Sjögren's syndrome: results of the BELISS open-label phase II study | Annals of the Rheumatic Diseases | 2015 | 248 |
| 8 | Specific plasma membrane protein phenotype of culture-amplified and native human bone marrow mesenchymal stem cells | Blood | 2008 | 238 |
| 9 | Interleukin-6 regulates pancreatic α-cell mass expansion | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 234 |
| 10 | Biomaterials Functionalized with MSC Secreted Extracellular Vesicles and Soluble Factors for Tissue Regeneration | Advanced Functional Materials | 2020 | 204 |
| 11 | The small heat shock proteins family: The long forgotten chaperones | International Journal of Biochemistry and Cell Biology | 2012 | 203 |
| 12 | Frontal lobe seizures: From clinical semiology to localization | Epilepsia | 2014 | 194 |
| 13 | Osteogenicity of biphasic calcium phosphate ceramics and bone autograft in a goat model | Biomaterials | 2008 | 183 |
| 14 | Danger signals – damaged-self recognition across the tree of life | Frontiers in Plant Science | 2014 | 171 |
| 15 | Diagnostic methods and treatment options for focal cortical dysplasia | Epilepsia | 2015 | 167 |
| 16 | Dormant, quiescent, tolerant and persister cells: Four synonyms for the same target in cancer | Biochemical Pharmacology | 2019 | 147 |
| 17 | ANKRD26-related thrombocytopenia and myeloid malignancies | Blood | 2013 | 145 |
| 18 | Overexpression of transfected cathepsin D in transformed cells increases their malignant phenotype and metastatic potency | Oncogene | 1990 | 144 |
| 19 | Differentiation In Vivo of Cardiac Committed Human Embryonic Stem Cells in Postmyocardial Infarcted Rats | Stem Cells | 2007 | 141 |
| 20 | Sexual Addictions | American Journal of Drug and Alcohol Abuse | 2010 | 141 |
| 21 | Heat Shock Protein 70 Neutralization Exerts Potent Antitumor Effects in Animal Models of Colon Cancer and Melanoma | Cancer Research | 2006 | 138 |
| 22 | Cell therapy induced regeneration of severely atrophied mandibular bone in a clinical trial | Stem Cell Research and Therapy | 2018 | 132 |
| 23 | Bone regeneration: stem cell therapies and clinical studies in orthopaedics and traumatology | Journal of Cellular and Molecular Medicine | 2011 | 116 |
| 24 | Reconstruction of Large Skeletal Defects: Current Clinical Therapeutic Strategies and Future Directions Using 3D Printing | Frontiers in Bioengineering and Biotechnology | 2020 | 109 |
| 25 | Biology of Bone Sarcomas and New Therapeutic Developments | Calcified Tissue International | 2018 | 106 |
| 26 | Bone Marrow Cells Can Give Rise to Ameloblast-like Cells | Journal of Dental Research | 2006 | 105 |
| 27 | PARP1 is activated at telomeres upon G4 stabilization: possible target for telomere-based therapy | Oncogene | 2010 | 103 |
| 28 | Hematologic Complications of Immune Checkpoint Inhibitors | Oncologist | 2019 | 103 |
| 29 | Pre-clinical studies of bone regeneration with human bone marrow stromal cells and biphasic calcium phosphate | Stem Cell Research and Therapy | 2014 | 100 |
| 30 | Different mechanisms operating during different critical time-windows reduce rat fetal beta cell mass due to a maternal low-protein or low-energy diet | Diabetologia | 2007 | 98 |
| 31 | Control of -Cell Differentiation by the Pancreatic Mesenchyme | Diabetes | 2007 | 96 |
| 32 | Emotional hyper‐reactivity in normothymic bipolar patients | Bipolar Disorders | 2009 | 96 |
| 33 | The direct effect of leptin on skeletal muscle thermogenesis is mediated by substrate cycling between de novo lipogenesis and lipid oxidation | FEBS Letters | 2004 | 95 |
| 34 | Contrast-Enhanced Sonography Helps in Discrimination of Benign From Malignant Adnexal Masses | Journal of Ultrasound in Medicine | 2004 | 93 |
| 35 | Artificial intelligence, machine (deep) learning and radio(geno)mics: definitions and nuclear medicine imaging applications | European Journal of Nuclear Medicine and Molecular Imaging | 2019 | 91 |
| 36 | OGX-427 inhibits tumor progression and enhances gemcitabine chemotherapy in pancreatic cancer | Cell Death and Disease | 2011 | 87 |
| 37 | SYNTHESIS: Evolutionary ecology of microbial wars: within‐host competition and (incidental) virulence | Evolutionary Applications | 2009 | 86 |
| 38 | Towards a European consensus for reporting incidental findings during clinical NGS testing | European Journal of Human Genetics | 2015 | 85 |
| 39 | Myeloid-derived suppressor cells from tumor-bearing mice impair TGF-β-induced differentiation of CD4+CD25+FoxP3+ Tregs from CD4+CD25−FoxP3− T cells | Journal of Leukocyte Biology | 2012 | 84 |
| 40 | Analysis of the role of autophagy inhibition by two complementary human cytomegalovirus BECN1/Beclin 1-binding proteins | Autophagy | 2016 | 82 |
| 41 | Advanced Monte Carlo simulations of emission tomography imaging systems with GATE | Physics in Medicine and Biology | 2021 | 82 |
| 42 | Performance of cardiac cadmium-zinc-telluride gamma camera imaging in coronary artery disease: a review from the cardiovascular committee of the European Association of Nuclear Medicine (EANM) | European Journal of Nuclear Medicine and Molecular Imaging | 2016 | 80 |
| 43 | Mineralocorticoid receptor antagonist pattern of use in heart failure with reduced ejection fraction: findings from BIOSTAT‐CHF | European Journal of Heart Failure | 2017 | 79 |
| 44 | Selective depletion of inducible HSP70 enhances immunogenicity of rat colon cancer cells | Oncogene | 2001 | 77 |
| 45 | Increased lipolysis in adipose tissue and lipid mobilization to natriuretic peptides during low-calorie diet in obese women | International Journal of Obesity | 2002 | 75 |
| 46 | The Dendritic Cell-Regulatory T Lymphocyte Crosstalk Contributes to Tumor-Induced Tolerance | Clinical and Developmental Immunology | 2011 | 75 |
| 47 | Estrogens increase the expression of fibulin-1, an extracellular matrix protein secreted by human ovarian cancer cells. | Proceedings of the National Academy of Sciences of the United States of America | 1996 | 74 |
| 48 | Regional and gender variations in adipose tissue lipolysis in response to weight loss | Journal of Lipid Research | 1999 | 74 |
| 49 | Post-transcriptional gene silencing mediated by microRNAs is controlled by nucleoplasmic Sfpq | Nature Communications | 2017 | 68 |
| 50 | Inferior In Vivo Osteogenesis and Superior Angiogeneis of Human Adipose-Derived Stem Cells Compared with Bone Marrow-Derived Stem Cells Cultured in Xeno-Free Conditions | Stem Cells Translational Medicine | 2017 | 67 |
