| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors | Nature | 2020 | 3,133 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 4 | Structure of the RNA-dependent RNA polymerase from COVID-19 virus | Science | 2020 | 1,228 |
| 5 | Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells | Nature Cell Biology | 2012 | 1,227 |
| 6 | Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease | Science | 2020 | 1,135 |
| 7 | BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection | Nature | 2022 | 889 |
| 8 | The Growth Factor Progranulin Binds to TNF Receptors and Is Therapeutic Against Inflammatory Arthritis in Mice | Science | 2011 | 644 |
| 9 | CD44 is of Functional Importance for Colorectal Cancer Stem Cells | Clinical Cancer Research | 2008 | 555 |
| 10 | Intraparticle Molecular Orbital Engineering of Semiconducting Polymer Nanoparticles as Amplified Theranostics for in Vivo Photoacoustic Imaging and Photothermal Therapy | ACS Nano | 2016 | 466 |
| 11 | ULK 1 translocates to mitochondria and phosphorylates FUNDC 1 to regulate mitophagy | EMBO Reports | 2014 | 435 |
| 12 | A Regulatory Signaling Loop Comprising the PGAM5 Phosphatase and CK2 Controls Receptor-Mediated Mitophagy | Molecular Cell | 2014 | 433 |
| 13 | Mechanisms Shaping the Membranes of Cellular Organelles | Annual Review of Cell and Developmental Biology | 2009 | 368 |
| 14 | Mitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy | Autophagy | 2016 | 367 |
| 15 | HBXIP-elevated methyltransferase METTL3 promotes the progression of breast cancer via inhibiting tumor suppressor let-7g | Cancer Letters | 2018 | 367 |
| 16 | Suppression of tumorigenesis by human mesenchymal stem cells in a hepatoma model | Cell Research | 2008 | 343 |
| 17 | Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug carmofur | Nature Structural and Molecular Biology | 2020 | 339 |
| 18 | Elevation of Highly Up-regulated in Liver Cancer (HULC) by Hepatitis B Virus X Protein Promotes Hepatoma Cell Proliferation via Down-regulating p18 | Journal of Biological Chemistry | 2012 | 332 |
| 19 | Penaeid shrimp genome provides insights into benthic adaptation and frequent molting | Nature Communications | 2019 | 328 |
| 20 | Long Noncoding RNA HULC Modulates Abnormal Lipid Metabolism in Hepatoma Cells through an miR-9–Mediated RXRA Signaling Pathway | Cancer Research | 2015 | 311 |
| 21 | Parkin Ubiquitinates Drp1 for Proteasome-dependent Degradation | Journal of Biological Chemistry | 2011 | 310 |
| 22 | Mitophagy, Mitochondrial Homeostasis, and Cell Fate | Frontiers in Cell and Developmental Biology | 2020 | 296 |
| 23 | Biochemical and Structural Insights into the Mechanisms of SARS Coronavirus RNA Ribose 2′-O-Methylation by nsp16/nsp10 Protein Complex | PLoS Pathogens | 2011 | 287 |
| 24 | Dkk-1 secreted by mesenchymal stem cells inhibits growth of breast cancer cells via depression of Wnt signalling | Cancer Letters | 2008 | 273 |
| 25 | Achieving Persistent, Efficient, and Robust Room‐Temperature Phosphorescence from Pure Organics for Versatile Applications | Advanced Materials | 2019 | 270 |
| 26 | Endothelialization and patency of RGD-functionalized vascular grafts in a rabbit carotid artery model | Biomaterials | 2012 | 265 |
| 27 | Recent advances in dynamic m 6 A RNA modification | Open Biology | 2016 | 265 |
| 28 | AMPK and Autophagy | Advances in Experimental Medicine and Biology | 2019 | 261 |
| 29 | A combined application of biochar and phosphorus alleviates heat-induced adversities on physiological, agronomical and quality attributes of rice | Plant Physiology and Biochemistry | 2016 | 256 |
| 30 | Integrating Enzymatic Self-Assembly and Mitochondria Targeting for Selectively Killing Cancer Cells without Acquired Drug Resistance | Journal of the American Chemical Society | 2016 | 254 |
| 31 | Fluorescence Resonance Energy Transfer Inhibition Assay for α-Fetoprotein Excreted during Cancer Cell Growth Using Functionalized Persistent Luminescence Nanoparticles | Journal of the American Chemical Society | 2011 | 248 |
| 32 | Semiconducting Oligomer Nanoparticles as an Activatable Photoacoustic Probe with Amplified Brightness for In Vivo Imaging of pH | Advanced Materials | 2016 | 248 |
| 33 | Regulating Near-Infrared Photodynamic Properties of Semiconducting Polymer Nanotheranostics for Optimized Cancer Therapy | ACS Nano | 2017 | 239 |
| 34 | The Vici Syndrome Protein EPG5 Is a Rab7 Effector that Determines the Fusion Specificity of Autophagosomes with Late Endosomes/Lysosomes | Molecular Cell | 2016 | 227 |
| 35 | Near Infrared Fluorescent Trypsin Stabilized Gold Nanoclusters as Surface Plasmon Enhanced Energy Transfer Biosensor and in Vivo Cancer Imaging Bioprobe | Analytical Chemistry | 2013 | 225 |
| 36 | Resveratrol protects against age-associated infertility in mice | Human Reproduction | 2013 | 221 |
| 37 | Mitophagy: An Emerging Role in Aging and Age-Associated Diseases | Frontiers in Cell and Developmental Biology | 2020 | 220 |
| 38 | Structures of the atlastin GTPase provide insight into homotypic fusion of endoplasmic reticulum membranes | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 212 |
| 39 | MicroRNA-145 Modulates N6-Methyladenosine Levels by Targeting the 3′-Untranslated mRNA Region of the N6-Methyladenosine Binding YTH Domain Family 2 Protein | Journal of Biological Chemistry | 2017 | 212 |
| 40 | Targeted Delivery of CRISPR/Cas9‐Mediated Cancer Gene Therapy via Liposome‐Templated Hydrogel Nanoparticles | Advanced Functional Materials | 2017 | 210 |
| 41 | Beclin 1 cleavage by caspase-3 inactivates autophagy and promotes apoptosis | Protein and Cell | 2010 | 208 |
| 42 | Calixarene‐Based Supramolecular AIE Dots with Highly Inhibited Nonradiative Decay and Intersystem Crossing for Ultrasensitive Fluorescence Image‐Guided Cancer Surgery | Angewandte Chemie - International Edition | 2020 | 208 |
| 43 | Selective autophagy of intracellular organelles: Recent research advances | Theranostics | 2021 | 207 |
| 44 | The sea cucumber genome provides insights into morphological evolution and visceral regeneration | PLoS Biology | 2017 | 202 |
| 45 | Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase | Nature Cell Biology | 2015 | 199 |
| 46 | Tandem Molecular Self‐Assembly in Liver Cancer Cells | Angewandte Chemie - International Edition | 2018 | 199 |
| 47 | A Powerful CD8+ T‐Cell Stimulating D‐Tetra‐Peptide Hydrogel as a Very Promising Vaccine Adjuvant | Advanced Materials | 2017 | 198 |
| 48 | Mitochondrial E3 ligase MARCH 5 regulates FUNDC 1 to fine‐tune hypoxic mitophagy | EMBO Reports | 2017 | 197 |
| 49 | Amperometric glucose biosensor based on multilayer films via layer-by-layer self-assembly of multi-wall carbon nanotubes, gold nanoparticles and glucose oxidase on the Pt electrode | Biosensors and Bioelectronics | 2007 | 196 |
| 50 | Effect of sustained heparin release from PCL/chitosan hybrid small-diameter vascular grafts on anti-thrombogenic property and endothelialization | Acta Biomaterialia | 2014 | 196 |
