# | Title | Journal | Year | Citations |
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1 | The Clinical Pharmacogenomics Implementation Consortium: CPIC Guideline for SLCO1B1 and Simvastatin-Induced Myopathy | Clinical Pharmacology and Therapeutics | 2012 | 294 |
2 | Chronic pain after thoracic surgery: a follow-up study | Acta Anaesthesiologica Scandinavica | 1999 | 286 |
3 | Grapefruit juice—simvastatin interaction: Effect on serum concentrations of simvastatin, simvastatin acid, and HMG-CoA reductase inhibitors* | Clinical Pharmacology and Therapeutics | 1998 | 283 |
4 | Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics and pharmacodynamics of repaglinide: potentially hazardous interaction between gemfibrozil and repaglinide | Diabetologia | 2003 | 269 |
5 | Erythromycin and verapamil considerably increase serum simvastatin and simvastatin acid concentrations* | Clinical Pharmacology and Therapeutics | 1998 | 267 |
6 | Role of OATP transporters in the disposition of drugs | Pharmacogenomics | 2007 | 241 |
7 | SLCO1B1 polymorphism and sex affect the pharmacokinetics of pravastatin but not fluvastatin | Clinical Pharmacology and Therapeutics | 2006 | 215 |
8 | Interactions with the Absorption of Tetracyclines | Drugs | 1976 | 194 |
9 | Cyclosporine markedly raises the plasma concentrations of repaglinide | Clinical Pharmacology and Therapeutics | 2005 | 180 |
10 | Role of Cytochrome P450 2C8 in Drug Metabolism and Interactions | Pharmacological Reviews | 2016 | 175 |
11 | Different effects of the ABCG2 c.421C>A SNP on the pharmacokinetics of fluvastatin, pravastatin and simvastatin | Pharmacogenomics | 2009 | 171 |
12 | Global analysis of genetic variation in SLCO1B1 | Pharmacogenomics | 2008 | 168 |
13 | Amitriptyline effectively relieves neuropathic pain following treatment of breast cancer | Pain | 1996 | 161 |
14 | Rifampin markedly decreases and gemfibrozil increases the plasma concentrations of atorvastatin and its metabolites | Clinical Pharmacology and Therapeutics | 2005 | 132 |
15 | PPARA: A Novel Genetic Determinant of CYP3A4 In Vitro and In Vivo | Clinical Pharmacology and Therapeutics | 2012 | 131 |
16 | Ciprofloxacin greatly increases concentrations and hypotensive effect of tizanidine by inhibiting its cytochrome P450 1A2?mediated presystemic metabolism | Clinical Pharmacology and Therapeutics | 2004 | 130 |
17 | Extradural, paravertebral and intercostal nerve blocks for post-thoracotomy pain | British Journal of Anaesthesia | 1995 | 128 |
18 | Itraconazole increases but grapefruit juice greatly decreases plasma concentrations of celiprolol | Clinical Pharmacology and Therapeutics | 2003 | 126 |
19 | Itraconazole prevents terfenadine metabolism and increases risk of torsades de pointes ventricular tachycardia | European Journal of Clinical Pharmacology | 1993 | 119 |
20 | Trimethoprim and the CYP2C8*3 Allele Have Opposite Effects on the Pharmacokinetics of Pioglitazone | Drug Metabolism and Disposition | 2008 | 110 |
21 | Plasma concentrations and effects of oral methylprednisolone are considerably increased by itraconazole* | Clinical Pharmacology and Therapeutics | 1998 | 103 |
22 | Drug-related deaths in a university central hospital | European Journal of Clinical Pharmacology | 2002 | 98 |
23 | Fluvoxamine drastically increases concentrations and effects of tizanidine: a potentially hazardous interaction*1 | Clinical Pharmacology and Therapeutics | 2004 | 98 |
24 | Effect of route of administration of fluconazole on the interaction between fluconazole and midazolam | European Journal of Clinical Pharmacology | 1997 | 89 |
25 | Oral contraceptives containing ethinyl estradiol and gestodene markedly increase plasma concentrations and effects of tizanidine by inhibiting cytochrome P450 1A2 | Clinical Pharmacology and Therapeutics | 2005 | 87 |
26 | Effects of orange juice on the pharmacokinetics of atenolol | European Journal of Clinical Pharmacology | 2005 | 86 |
27 | Drug interactions with oral antidiabetic agents: pharmacokinetic mechanisms and clinical implications | Trends in Pharmacological Sciences | 2012 | 85 |
28 | Effects of Daily Ingestion of Cranberry Juice on the Pharmacokinetics of Warfarin, Tizanidine, and Midazolam—Probes of CYP2C9, CYP1A2, and CYP3A4 | Clinical Pharmacology and Therapeutics | 2007 | 84 |
29 | Different Effects of SLCO1B1 Polymorphism on the Pharmacokinetics and Pharmacodynamics of Repaglinide and Nateglinide | Journal of Clinical Pharmacology | 2008 | 83 |
30 | Intravenous Lipid Emulsion Sequesters Amiodarone in Plasma and Eliminates Its Hypotensive Action in Pigs | Annals of Emergency Medicine | 2010 | 80 |
31 | Itraconazole, gemfibrozil and their combination markedly raise the plasma concentrations of loperamide | European Journal of Clinical Pharmacology | 2006 | 79 |
32 | Prescription drugs during pregnancy and lactation—a Finnish register-based study | European Journal of Clinical Pharmacology | 2003 | 74 |
33 | Pharmacogenetics of cyclosporine in children suggests an age-dependent influence of ABCB1 polymorphisms | Pharmacogenetics and Genomics | 2008 | 71 |
34 | Carboxylesterase 1 c.428G>A single nucleotide variation increases the antiplatelet effects of clopidogrel by reducing its hydrolysis in humans | Clinical Pharmacology and Therapeutics | 2015 | 70 |
35 | Pharmacokinetics and Pharmacodynamics of Intravenous Inotropic Agents | Clinical Pharmacokinetics | 2004 | 69 |
36 | Carboxylesterase 1 Polymorphism Impairs Oseltamivir Bioactivation in Humans | Clinical Pharmacology and Therapeutics | 2012 | 64 |
37 | Methylprednisolone in Neonatal Cardiac Surgery: Reduced Inflammation Without Improved Clinical Outcome | Annals of Thoracic Surgery | 2013 | 64 |
38 | Repeated consumption of grapefruit juice considerably increases plasma concentrations of cisapride | Clinical Pharmacology and Therapeutics | 1999 | 59 |
39 | Dose-Dependent Interaction between Gemfibrozil and Repaglinide in Humans: Strong Inhibition of CYP2C8 with Subtherapeutic Gemfibrozil Doses | Drug Metabolism and Disposition | 2011 | 58 |
40 | Developmental pharmacokinetics of ciclosporin – a population pharmacokinetic study in paediatric renal transplant candidates | British Journal of Clinical Pharmacology | 2007 | 54 |
41 | Grapefruit Juice Inhibits the Metabolic Activation of Clopidogrel | Clinical Pharmacology and Therapeutics | 2014 | 49 |
42 | Prevention of chemotherapy‐induced cachexia by ACVR2B ligand blocking has different effects on heart and skeletal muscle | Journal of Cachexia, Sarcopenia and Muscle | 2018 | 48 |
43 | Effects of the Antifungals Voriconazole and Fluconazole on the Pharmacokinetics of S -(+)- and R -(−)-Ibuprofen | Antimicrobial Agents and Chemotherapy | 2006 | 47 |
44 | Oxycodone clearance is markedly reduced with advancing age: a population pharmacokinetic study | British Journal of Anaesthesia | 2012 | 45 |
45 | Intravenous Lipid Emulsion Entraps Amitriptyline into Plasma and Can Lower its Brain Concentration – An Experimental Intoxication Study in Pigs | Basic and Clinical Pharmacology and Toxicology | 2013 | 45 |
46 | Telithromycin, but not montelukast, increases the plasma concentrations and effects of the cytochrome P450 3A4 and 2C8 substrate repaglinide | Clinical Pharmacology and Therapeutics | 2006 | 44 |
47 | Intravenous Lipid Emulsion Given to Volunteers does not Affect Symptoms of Lidocaine Brain Toxicity | Basic and Clinical Pharmacology and Toxicology | 2015 | 43 |
48 | Rifampicin has a Profound Effect on the Pharmacokinetics of Oral S‐Ketamine and Less on Intravenous S‐Ketamine | Basic and Clinical Pharmacology and Toxicology | 2012 | 42 |
49 | Transporter‐Mediated Alterations in Patients With NASH Increase Systemic and Hepatic Exposure to an OATP and MRP2 Substrate | Clinical Pharmacology and Therapeutics | 2018 | 41 |
50 | The effect of continuous intravenous indomethacin infusion on bleeding time and postoperative pain in patients undergoing emergency surgery of the lower extremities | Acta Anaesthesiologica Scandinavica | 1989 | 39 |