845(top 1%)
papers
31.9K(top 1%)
citations
83(top 1%)
h-index
136(top 1%)
g-index
911
all documents
35.3K
doc citations
3.8K
citing journals

Top Articles

#TitleJournalYearCitations
1Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1Autophagy20211,430
2KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesisNature Medicine2015869
3The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 ActivityCell Reports2017608
4Validating novel tau positron emission tomography tracer [F‐18]‐AV‐1451 (T807) on postmortem brain tissueAnnals of Neurology2015535
5Chemical genetics of Plasmodium falciparumNature2010515
6Sustained cyclic AMP production by parathyroid hormone receptor endocytosisNature Chemical Biology2009502
7Skeletal Muscle Triglycerides, Diacylglycerols, and Ceramides in Insulin ResistanceDiabetes2011340
8Neural Control of the Lower Urinary Tract2015337
9Small Molecule Signaling Agents: The Integrated Chemistry and Biochemistry of Nitrogen Oxides, Oxides of Carbon, Dioxygen, Hydrogen Sulfide, and Their Derived SpeciesChemical Research in Toxicology2012330
10Lipotoxicity Causes Multisystem Organ Failure and Exacerbates Acute Pancreatitis in ObesityScience Translational Medicine2011328
11Versatile and multivalent nanobodies efficiently neutralize SARS-CoV-2Science2020306
12Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c releaseProceedings of the National Academy of Sciences of the United States of America2017285
13A Novel Role for the Dioxin Receptor in Fatty Acid Metabolism and Hepatic SteatosisGastroenterology2010228
14Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineagesNature Chemical Biology2009221
15Retromer terminates the generation of cAMP by internalized PTH receptorsNature Chemical Biology2011205
16PXR and CAR in energy metabolismTrends in Endocrinology and Metabolism2009203
17Cutaneous TRPV1+ Neurons Trigger Protective Innate Type 17 Anticipatory ImmunityCell2019202
18Thrombospondin-1 Inhibits VEGF Receptor-2 Signaling by Disrupting Its Association with CD47Journal of Biological Chemistry2010199
19Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repairNature2011190
20Applications for α-lactalbumin in human nutritionNutrition Reviews2018186
21Structure and dynamics of the active human parathyroid hormone receptor-1Science2019185
22Transduction of Redox Signaling by Electrophile-Protein ReactionsScience Signaling2009184
23Unlocking Biomarker Discovery: Large Scale Application of Aptamer Proteomic Technology for Early Detection of Lung CancerPLoS ONE2010183
24Electrophilic Nitro-fatty Acids Activate NRF2 by a KEAP1 Cysteine 151-independent MechanismJournal of Biological Chemistry2011182
25PTH receptor-1 signalling—mechanistic insights and therapeutic prospectsNature Reviews Endocrinology2015179
26Quantitative PCR-Based Measurement of Nuclear and Mitochondrial DNA Damage and Repair in Mammalian CellsMethods in Molecular Biology2014179
27Nuclear receptor PXR, transcriptional circuits and metabolic relevanceBiochimica Et Biophysica Acta - Molecular Basis of Disease2011177
28Germinal center B cells selectively oxidize fatty acids for energy while conducting minimal glycolysisNature Immunology2020172
29Endogenous generation and protective effects of nitro-fatty acids in a murine model of focal cardiac ischaemia and reperfusionCardiovascular Research2010171
30Cryo-EM Structure of the Human Cannabinoid Receptor CB2-Gi Signaling ComplexCell2020167
31Fatty acid synthase is up-regulated during hepatitis C virus infection and regulates hepatitis C virus entry and productionHepatology2008164
32Alternative Lengthening of Telomeres and Loss of DAXX/ATRX Expression Predicts Metastatic Disease and Poor Survival in Patients with Pancreatic Neuroendocrine TumorsClinical Cancer Research2017164
33Molecular recognition of nitrated fatty acids by PPARγNature Structural and Molecular Biology2008161
34Automated High-Content Live Animal Drug Screening Using C. elegans Expressing the Aggregation Prone Serpin α1-antitrypsin ZPLoS ONE2010160
35Synaptic recruitment of gephyrin regulates surface GABAA receptor dynamics for the expression of inhibitory LTPNature Communications2014158
36Phospho-selective mechanisms of arrestin conformations and functions revealed by unnatural amino acid incorporation and 19F-NMRNature Communications2015156
37Covalent Peroxisome Proliferator-activated Receptor γ Adduction by Nitro-fatty AcidsJournal of Biological Chemistry2010151
38Nrf2-dependent and -independent Responses to Nitro-fatty Acids in Human Endothelial CellsJournal of Biological Chemistry2009150
39Targeting Nrf2-Mediated Gene Transcription by Extremely Potent Synthetic Triterpenoids Attenuate Dopaminergic Neurotoxicity in the MPTP Mouse Model of Parkinson's DiseaseAntioxidants and Redox Signaling2013150
40Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signalingProceedings of the National Academy of Sciences of the United States of America2018150
41Constitutive activities of estrogen-related receptors: Transcriptional regulation of metabolism by the ERR pathways in health and diseaseBiochimica Et Biophysica Acta - Molecular Basis of Disease2015148
42Noncanonical GPCR signaling arising from a PTH receptor–arrestin–Gβγ complexProceedings of the National Academy of Sciences of the United States of America2013141
43Targeting the EMT transcription factor TWIST1 overcomes resistance to EGFR inhibitors in EGFR-mutant non-small-cell lung cancerOncogene2019140
44Structural insights into the human D1 and D2 dopamine receptor signaling complexesCell2021140
45Combined Analysis of Estrogen Receptor β-1 and Progesterone Receptor Expression Identifies Lung Cancer Patients with Poor OutcomeClinical Cancer Research2011139
46NRF2 Induction Supporting Breast Cancer Cell Survival Is Enabled by Oxidative Stress–Induced DPP3–KEAP1 InteractionCancer Research2017138
47Following Cytochrome c Release, Autophagy Is Inhibited during Chemotherapy-Induced Apoptosis by Caspase 8–Mediated Cleavage of Beclin 1Cancer Research2011134
48Overcoming Temozolomide Resistance in Glioblastoma via Dual Inhibition of NAD+ Biosynthesis and Base Excision RepairCancer Research2011134
49A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncologyNature Cancer2022133
50NRF2/ARE pathway negatively regulates BACE1 expression and ameliorates cognitive deficits in mouse Alzheimer’s modelsProceedings of the National Academy of Sciences of the United States of America2019132