Department of Medicine

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#	Title	Journal	Year	Citations
1	SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin	Nature	2008	945
2	Diversity and clonal selection in the human T-cell repertoire	Proceedings of the National Academy of Sciences of the United States of America	2014	622
3	The pancreatic stellate cell: a star on the rise in pancreatic diseases	Journal of Clinical Investigation	2007	588
4	Evaluation of Patients With Pulmonary Nodules: When Is It Lung Cancer?	Chest	2007	470
5	Imprinting of the Angelman syndrome gene, UBE3A, is restricted to brain	Nature Genetics	1997	297
6	Racial Differences in Blood Pressure Control: Potential Explanatory Factors	American Journal of Medicine	2006	201
7	Regulation of telomerase by alternate splicing of human telomerase reverse transcriptase (hTERT) in normal and neoplastic ovary, endometrium and myometrium	International Journal of Cancer	2000	174
8	Extracellular Transglutaminase 2 Is Catalytically Inactive, but Is Transiently Activated upon Tissue Injury	PLoS ONE	2008	174
9	Chronic hepatitis, hepatocyte fragility, and increased soluble phosphoglycokeratins in transgenic mice expressing a keratin 18 conserved arginine mutant.	Journal of Cell Biology	1995	156
10	Keratins: Guardians of the liver	Hepatology	2002	143
11	Tissue-specific alternate splicing of human telomerase reverse transcriptase (hTERT) influences telomere lengths during human development	International Journal of Cancer	2001	131
12	Susceptibility to hepatotoxicity in transgenic mice that express a dominant-negative human keratin 18 mutant.	Journal of Clinical Investigation	1996	119
13	Hemin-activated macrophages home to the pancreas and protect from acute pancreatitis via heme oxygenase-1 induction	Journal of Clinical Investigation	2005	113
14	Mutation of human keratin 18 in association with cryptogenic cirrhosis.	Journal of Clinical Investigation	1997	109
15	Hypertension Intervention Nurse Telemedicine Study (HINTS): Testing a multifactorial tailored behavioral/educational and a medication management intervention for blood pressure control	American Heart Journal	2007	101
16	Dominant Role for Regulatory T Cells in Protecting Females Against Pulmonary Hypertension	Circulation Research	2018	97
17	Intermediate filament proteins of the liver: Emerging disease association and functions	Hepatology	1997	89
18	Clinician awareness of adherence to hypertension guidelines	American Journal of Medicine	2004	88
19	Patient education and provider decision support to control blood pressure in primary care: A cluster randomized trial	American Heart Journal	2009	87
20	Removal of the Protein-Bound Solutes Indican and P-Cresol Sulfate by Peritoneal Dialysis	Clinical Journal of the American Society of Nephrology: CJASN	2008	86
21	Divergent patterns of telomere maintenance mechanisms among human sarcomas: Sharply contrasting prevalence of the alternative lengthening of telomeres mechanism in Ewing's sarcomas and osteosarcomas	Genes Chromosomes and Cancer	2004	85
22	Surgical Options for the Treatment of Obstructive Sleep Apnea	Medical Clinics of North America	2010	85
23	National Trends in Outcomes Among Elderly Patients with Heart Failure	American Journal of Medicine	2006	84
24	Keratin 20 Helps Maintain Intermediate Filament Organization in Intestinal Epithelia	Molecular Biology of the Cell	2003	83
25	Immunity to Calicivirus Infection	Journal of Infectious Diseases	2000	81
26	Symmetric and Asymmetric DNA Methylation in the Human IGF2–H19 Imprinted Region	Genomics	2000	78
27	Keratin modifications and solubility properties in epithelial cells and in vitro	Sub-Cellular Biochemistry	1998	73
28	Relationship between insulin-mediated glucose disposal and regulation of plasma and adipose tissue lipoprotein lipase	Diabetologia	1997	72
29	Dissociation of IGF2 and H19 imprinting in human brain	Brain Research	1998	66
30	Sodium octanoate to reverse indoxyl sulfate and p-cresyl sulfate albumin binding in uremic and normal serum during sample preparation followed by fluorescence liquid chromatography	Journal of Chromatography A	2009	65
31	Diversification of the antigen-specific T cell receptor repertoire after varicella zoster vaccination	Science Translational Medicine	2016	64
32	Tissue-Specific Expression of Antisense and Sense Transcripts at the Imprinted Gnas Locus	Genomics	2000	63
33	Nuclear-Encoded lncRNA MALAT1 Epigenetically Controls Metabolic Reprogramming in HCC Cells through the Mitophagy Pathway	Molecular Therapy - Nucleic Acids	2021	61
34	Allele-Specific Histone Acetylation Accompanies Genomic Imprinting of the Insulin-Like Growth Factor II Receptor Gene**Supported by NIH Grant DK-36054 and by the Research Service of the Department of Veterans Affairs.	Endocrinology	2000	58
35	A novel orthotopic tumor model to study growth factors and oncogenes in hepatocarcinogenesis	Clinical Cancer Research	2003	57
36	The Role of Histone Acetylation in the Allelic Expression of the Imprinted Human Insulin-like Growth Factor II Gene	Biochemical and Biophysical Research Communications	1998	54
37	The Relationship Between B-type Natriuretic Peptide and Health Status in Patients With Heart Failure	Journal of Cardiac Failure	2005	53
38	The effect of assessment method and respondent population on utilities elicited for Gaucher disease	Quality of Life Research	1997	52
39	Efficacy of esomeprazole in controlling reflux symptoms, intraesophageal, and intragastric pH in patients with Barrett’s esophagus*	Ecological Management and Restoration	2003	51
40	Organ-specific stress induces mouse pancreatic keratin overexpression in association with NF-κB activation	Journal of Cell Science	2004	51
41	β-Adrenergic Receptor Activation Inhibits Keratinocyte Migration via a Cyclic Adenosine Monophosphate-independent Mechanism	Journal of Investigative Dermatology	2002	49
42	Detection of Sessile Serrated Adenomas in the Proximal Colon Using Wide-Field Fluorescence Endoscopy	Gastroenterology	2017	49
43	Lack of Reciprocal Genomic Imprinting of Sense and Antisense RNA of Mouse Insulin-like Growth Factor II Receptor in the Central Nervous System1	Biochemical and Biophysical Research Communications	1999	46
44	The veterans' study to improve the control of hypertension (V-STITCH): design and methodology	Contemporary Clinical Trials	2005	45
45	A small pericardial effusion is a marker of increased mortality	American Heart Journal	2011	45
46	Leukotrienes in Tumor-Associated Inflammation	Frontiers in Pharmacology	2020	45
47	Directing DNA Methylation to Inhibit Gene Expression	Cellular and Molecular Neurobiology	2006	37
48	Epigenetic regulation ofIgf2/H19 imprinting at CTCF insulator binding sites	Journal of Cellular Biochemistry	2003	36
49	Cross-species clues of an epigenetic imprinting regulatory code for the IGF2R gene	Cytogenetic and Genome Research	2006	36
50	Patient‐Centered Medical Home Implementation and Improved Chronic Disease Quality: A Longitudinal Observational Study	Health Services Research	2018	36

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